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Helper T cells can stimulate the proliferation of cytotoxic T cells but not that of B cells.

A) True
B) False

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In the presence of activated complement, neutrophils


A) are repelled
B) produce histamine
C) cause vasodilation
D) degranulate and release enzymes that cause tissue damage

E) All of the above
F) B) and C)

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D

Arrange the following events in the proper order in which they occur during an allergic response. 1 = Individual experiences symptoms 2 = Individual is sensitized to antigen 3 = IgE attaches to mast cells 4 = Antigen binds to IgE


A) 1, 2, 3, 4
B) 1, 3, 4, 2
C) 2, 3, 1, 4
D) 2, 3, 4, 1
E) 2, 4, 3, 1

F) A) and B)
G) D) and E)

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Immune complexes consist of


A) antibody plus complement
B) basophil plus complement
C) antigen plus antibody
D) antigen plus complement

E) A) and B)
F) A) and C)

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T cells are divided into two primary groups, effector and regulatory. Which of the following are regulatory T cells?


A) helper T cells
B) cytotoxic T cells
C) chemotaxic T cells
D) delayed hypersensitivity T cells
E) assistant T cells

F) C) and D)
G) A) and B)

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A

People with type O blood can be universal donors because their red blood cells do not contain either A antigen or B antigen on their surface.


A) True
B) False

C) A) and B)
D) undefined

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What is the cell that is responsible for a secondary antibody response to an antigen?


A) Memory B cell
B) Plasma cell
C) Cytotoxic T cell
D) All of the above are responsible

E) B) and C)
F) A) and D)

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With advancing age, the lymphatic system


A) Becomes less efficient at absorbing dietary lipids
B) Ceases to transport lymph
C) Produces an increasing number and variety of B-lymphocytes
D) Is less responsive to antigens
E) All choices are correct

F) B) and E)
G) C) and E)

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Most intermediate size antigen antibody complexes are removed by phagocytosis.


A) True
B) False

C) A) and B)
D) undefined

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For a hypersensitivity response to occur, two bound IgE molecules on a mast cell must react with a specific antigen.


A) True
B) False

C) A) and B)
D) undefined

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An individual antibody is made against


A) a whole bacterial cell
B) one epitope on the cell
C) one antigen on the cell
D) all of the combined antigenic determinants on a cell
E) the cell's DNA

F) B) and D)
G) D) and E)

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Cytotoxic T cells produce


A) class II MHCs
B) self proteins
C) antibodies, which make holes in cell membrane of infected cells
D) perforin, which makes holes in cell membrane of infected cells

E) None of the above
F) A) and B)

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D

Many different antibodies can be made against a single antigen.


A) True
B) False

C) A) and B)
D) undefined

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A hypersensitivity reaction occurs


A) during the first exposure to an antigen.
B) during a second or subsequent exposure to an antigen.
C) in individuals with diseases of the immune system.
D) only in children.
E) only in individuals with asthma.

F) C) and D)
G) C) and E)

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Tonsils


A) increase in size in adults.
B) are located in both the oral and abdominal cavities.
C) provide protection against bacteria entering the oral and nasal cavities.
D) contain red pulp and white pulp.
E) are not functional in children.

F) A) and B)
G) B) and C)

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An antigen presenting cell presents antigen to a T helper cell


A) inside a vesicle
B) on its surface on a class I MHC
C) on its surface on a class II MHC
D) on its surface attached to an antibody

E) None of the above
F) A) and B)

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Which of the following is the molecule that displays an antigen on the surface of cells?


A) Antigenic determinant
B) Antibody
C) Antigen receptor
D) Major histocompatibility complex molecule

E) None of the above
F) All of the above

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Histamine released by mast cells leads to all of the following symptoms except


A) capillary dilation
B) airway constriction
C) high fever
D) mucus secretion
E) itching

F) A) and D)
G) C) and E)

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Skin lesions due to hypersensitivity appear


A) 24 hours after first exposure to antigen
B) 48-72 hours after first exposure to antigen
C) 24 hours after second exposure to antigen
D) 3 weeks after second exposure to antigen

E) None of the above
F) C) and D)

Correct Answer

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Helper T cells interact with target cells by recognizing


A) antigens only.
B) MHC proteins only.
C) antigen-MHC protein complexes.
D) either antigens or MHC proteins.
E) neither antigens nor MHC proteins.

F) C) and D)
G) A) and E)

Correct Answer

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