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The amount of filtrate produced per minute is called the


A) renal fraction.
B) filtration fraction.
C) glomerular filtration rate.
D) clearance fraction.
E) renal rate.

F) C) and D)
G) A) and D)

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Once inside the cells of the ascending limb,potassium and chloride cross the basal membrane into the interstitial fluid by the process of


A) facilitated diffusion.
B) cotransport.
C) counter transport.
D) active transport.
E) simple diffusion.

F) C) and D)
G) A) and C)

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Angiotensin II


A) is a potent vasodilator.
B) stimulates aldosterone secretion.
C) is formed from angiotensin I by the action of renin.
D) acts on the collecting ducts to increase reabsorption of water.
E) decreases blood pressure.

F) A) and E)
G) C) and D)

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Which of the following would help maintain the medullary concentration gradient?


A) movement of urea from the distal convoluted tubule to the proximal convoluted tubule
B) urea movement from the collecting duct to medullary interstitial fluid
C) movement of water from the ascending limb into the medullary interstitial fluid
D) active transport of sodium and chloride from the medullary interstitial fluid into the collecting duct
E) urea movement into the collecting duct

F) B) and E)
G) B) and D)

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The part of the cardiac output that passes through the kidneys is the


A) renal fraction.
B) filtration fraction.
C) clearance fraction.
D) glomerular flow rate.
E) cardiac fraction.

F) B) and E)
G) All of the above

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Tubular secretion occurs in which of the following structures?


A) glomerulus
B) urethra
C) renal pelvis
D) distal convoluted tubule
E) collecting duct

F) A) and D)
G) A) and C)

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When sodium is actively transported from tubular cells to the interstitial fluid,


A) no energy is needed.
B) glucose and amino acids are countertransported at the same time.
C) Na+ concentration gradient is established between the tubule lumen and tubule cell.
D) water is countertransported by carrier molecules.
E) water is secreted.

F) B) and D)
G) A) and B)

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Tubular load refers to the amount of a given substance that


A) is present in the blood as it enters the afferent arteriole of the nephron.
B) passes through the filtration membrane into the nephron each minute.
C) can be actively reabsorbed from the filtrate.
D) can be secreted into the filtrate.
E) None of these choices is correct.

F) All of the above
G) A) and B)

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Which of the following structures is a capillary?


A) glomerulus
B) loop of Henle
C) collecting duct
D) Bowman's capsule
E) proximal convoluted tubule

F) B) and E)
G) A) and B)

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The inner layer of Bowman's capsule consists of specialized cells called


A) nephrons.
B) podocytes.
C) nephrocytes.
D) juxtamedullary cells.
E) macula densa.

F) B) and E)
G) A) and B)

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Which of the following helps maintain a high solute concentration in the kidney medulla?


A) high urea concentration in medulla
B) active transport of solutes from ascending limb
C) the vasa recta
D) functions of the loop of Henle
E) All of these choices are correct

F) All of the above
G) B) and C)

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Urine drains from the nephron into the calyces through the


A) loop of Henle.
B) collecting duct.
C) distal convoluted tubule.
D) proximal convoluted tubule.
E) Bowman's capsule.

F) A) and B)
G) A) and C)

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In the ascending limb of the loop of Henle,


A) water can easily enter or leave.
B) potassium and chloride are cotransported with sodium across the apical membrane.
C) calcium ions are actively transported across the basal membrane.
D) potassium is concentrated in the filtrate.
E) the filtrate does not change.

F) A) and E)
G) A) and D)

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Which of the following layers of the filtration membrane is closest to the plasma?


A) podocytes
B) macula densa
C) glomerular endothelium
D) the basement membrane
E) parietal layer of Bowman's capsule

F) C) and E)
G) B) and E)

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A substance that is useful for determining the plasma clearance rate of the kidney is


A) ADH.
B) glucose.
C) inulin.
D) protein.
E) ammonia.

F) D) and E)
G) A) and D)

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Urine is carried from the kidneys to the urinary bladder by the


A) urethra.
B) ureter.
C) calyces.
D) renal columns.
E) renal tubules.

F) A) and C)
G) A) and E)

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Urine is prevented from flowing back into the ureters from the bladder by ________________.


A) compression of the ureteral openings
B) the external urethral sphincter
C) the internal urethral sphincter
D) the ureteral sphincters
E) ureteral valves

F) None of the above
G) A) and D)

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Cortical tissue located between the pyramids is called the


A) calyx tissue.
B) renal papillae.
C) renal columns.
D) medullary rays.
E) renal corpuscles.

F) A) and D)
G) B) and E)

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The proximal convoluted tubule is


A) lined with epithelial cells that lack microvilli.
B) the site of glucose and amino acid reabsorption.
C) permeable to water if ADH is present.
D) impermeable to water.
E) the site of water secretion.

F) A) and B)
G) A) and E)

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What is tubular reabsorption?


A) The process where the nephron returns water and some filtered molecules to the blood.
B) The reabsorption of blood cells in the nephron into the body.
C) The passage of water and ions into the filtrate during filtration in the nephron.
D) The absorption of proteins into the filtrate which later becomes urine.
E) The transport additional solutes from the blood into the filtrate by tubule cells.

F) A) and E)
G) B) and C)

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