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Calcium-induced calcium release occurs when


A) calcium from the sarcoplasmic reticulum stimulates the movement of calcium into the cell through the plasma membrane.
B) calcium is released from both the sarcoplasmic reticulum and the cardiac muscle cell.
C) the eflux of calcium from the cell results in depolarization.
D) calcium entering through the plasma membrane stimulates release of calcium from the sarcoplasmic reticulum.

E) A) and B)
F) C) and D)

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The period of time in which the myocardium is insensitive to further stimulation is called the


A) absolute refractory period.
B) hyperpolarization period.
C) AV period.
D) SA period.
E) ectopic focus.

F) B) and E)
G) None of the above

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The "pacemaker" of the heart is the


A) right bundle branch.
B) left bundle branch.
C) AV node.
D) SA node.
E) PM node.

F) B) and E)
G) B) and D)

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Which of the following phrases would apply to cardiac muscle cells?


A) are organized in parallel columns or bundles
B) contain actin but no myosin
C) develop a significant oxygen debt during systole
D) are multinucleated like skeletal muscle cells
E) possess special cell-to-cell contacts called intercalated discs

F) B) and C)
G) A) and E)

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If the heart receives more sympathetic stimulation than parasympathetic stimulation,the heart will


A) increase its rate and force of contraction.
B) contract with greater force but at a slower rate.
C) decrease both its rate and force of contraction.
D) contract with less force but at a faster rate.
E) decrease rate,but increase force of contraction.

F) C) and D)
G) B) and E)

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When comparing cardiac muscle cells and skeletal muscle cells,


A) the rate of action potential propagation is faster in cardiac muscle.
B) both possess intercalated discs.
C) only skeletal muscle has a plateau phase in its contraction cycle.
D) action potentials are conducted from cell to cell only in cardiac muscle.
E) both are voluntary.

F) None of the above
G) C) and D)

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Which of the following factors would cause an increase in heart rate?


A) increased parasympathetic stimulation
B) stimulation of baroreceptors in the aorta
C) increased epinephrine release from the adrenal medulla
D) increased production of atrial natriuretic factor
E) vagal stimulation

F) C) and E)
G) All of the above

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Fred was admitted to the cardiac unit with chest pains.No arrhythmias and no large changes in the heart rate were observable.Blood samples taken over the next few days showed no increase in enzymes such as creatine phosphokinase.A possible treatment of the condition is


A) beta adrenergic blocking agents.
B) nitroglycerin.
C) calcium channel blocking agents.
D) aspirin.
E) exercise.

F) A) and D)
G) B) and C)

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From the right ventricle,blood flows directly into the _____.


A) aorta
B) right atrium
C) pulmonary trunk
D) pulmonary arteries
E) pulmonary veins

F) A) and C)
G) B) and E)

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Which of the following is true?


A) Blood enters the right and left atria only during diastole.
B) Most ventricular filling occurs before the atria contract.
C) During ventricular systole,the AV valves open.
D) The semilunar valves remain closed throughout ventricular systole.
E) Most of end-diastolic volume comes from active filling.

F) A) and E)
G) A) and B)

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What action is most responsible for the resting membrane potential in cardiac muscle cells?


A) movement of K+ through voltage-gated K+ channels
B) movement of Na+ through open Na+ channels
C) movement of Ca2+ through voltage-gated Ca2+ channels.
D) closing of Na+ and K+ voltage-gated channels

E) A) and B)
F) B) and D)

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Small changes in _____________ will have a large impact on the heart's pumping effectiveness,while large changes in ___________ do not impact the effectiveness much.


A) afterload; preload
B) preload; afterload
C) contractility; preload
D) afterload; contractility
E) contractility; afterload

F) B) and C)
G) A) and E)

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Contraction of the papillary muscles would


A) eject blood from the ventricles.
B) prevent the AV valves from protruding into the atria.
C) close the semilunar valves.
D) cause the atria to eject their contents into the ventricles.
E) open the semilunar valves.

F) B) and C)
G) A) and B)

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The epicardium


A) covers the surface of the heart.
B) lines the walls of the ventricles.
C) is known as the fibrous pericardium.
D) attaches inferiorly to the diaphragm.
E) is also called endocardium.

F) A) and B)
G) C) and E)

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Ventricular contraction begins at the


A) AV bundle.
B) apex of the heart.
C) base of the heart.
D) superior portion of the interventricular septum.
E) top of the ventricles.

F) B) and C)
G) A) and E)

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Lowered extracellular potassium levels will lower the heart rate because


A) the resting membrane potential is hyperpolarized.
B) ectopic action potentials occur.
C) action potential amplitude declines.
D) more sodium channels open.
E) it blocks calcium channels.

F) A) and B)
G) B) and D)

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Which of the following heart chambers is correctly associated with the blood vessel that enters or leaves it?


A) right atrium - pulmonary veins
B) left atrium - aorta
C) right ventricle - pulmonary trunk
D) left ventricle - superior vena cava and inferior vena cava
E) right atrium - aorta

F) C) and D)
G) A) and B)

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What cardiac arrhythmia will have no QRS complex as a symptom?


A) atrial fibrillation
B) ventricular fibrillation
C) bradycardia
D) premature ventricular contractions

E) None of the above
F) B) and D)

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Which vessels empty blood into the left atrium?


A) aorta
B) right atrium
C) pulmonary trunk
D) pulmonary arteries
E) pulmonary veins

F) A) and E)
G) A) and D)

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A serious condition in which a large amount of fluid accumulates in the pericardial cavity and puts pressure of the heart is


A) endocarditis.
B) pericarditis.
C) a myocardial infarction.
D) cardiac tamponade.

E) A) and B)
F) B) and D)

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