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Phagocytosis of either microbes or microbial constituents by macrophages is followed by the activation of macrophages and the secretion of cytokines.What are the main effects of these molecules?

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The cytokines released by activated macr...

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Why does it take approximately a week after infection for the benefits of an adaptive immune response to start to be felt?

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Before the establishment of an effector ...

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Identify the incorrect statement regarding hematopoiesis.


A) Hematopoiesis is a continuous process that occurs throughout one's lifetime.
B) The location for hematopoiesis differs with age.
C) Self renewal is necessary to replenish the supply of hematopoietic stem cells.
D) Most hematopoiesis occurs in the bone marrow after birth.
E) Leukocytes,but not erythrocytes,must go through hematopoiesis in order to develop.

F) A) and B)
G) C) and D)

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The last cases of smallpox were reported in the _____.


A) 1950s
B) 1960s
C) 1970s
D) 1980s
E) 1990s.

F) C) and D)
G) B) and D)

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_____ act as cellular messengers by delivering degraded pathogens to lymphoid organs.


A) Plasma cells
B) Dendritic cells
C) Large granular lymphocytes
D) Mast cells
E) Basophils.

F) None of the above
G) A) and E)

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Primary lymphoid tissues are the sites where lymphocytes _______,whereas secondary lymphoid tissues are the sites where lymphocytes _______.


A) are stimulated; develop and mature
B) encounter pathogens; undergo apoptosis
C) develop and mature; become stimulated
D) undergo clonal selection; differentiate from hematopoietic stem cells
E) die; are phagocytosed after death.

F) A) and E)
G) A) and B)

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Which of the following is not associated with mucosal surfaces?


A) mucus-secreting goblet cells
B) lysozyme
C) M cells
D) white pulp
E) beating cilia.

F) B) and D)
G) A) and E)

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Examples of granulocytes include all of the following except:


A) neutrophil
B) monocyte
C) basophil
D) eosinophil.
E) All of the above are examples of granulocytes.

F) A) and E)
G) B) and C)

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_____ cells persist long after an individual has been vaccinated.


A) Neutrophil
B) Plasma
C) Memory
D) M
E) Mast.

F) D) and E)
G) All of the above

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Which of the following statements regarding neutrophils is false?


A) Neutrophils are mobilized from the bone marrow to sites of infection when needed.
B) Neutrophils are active only in aerobic conditions.
C) Neutrophils are phagocytic.
D) Neutrophils form pus,which comprises dead neutrophils.
E) Dead neutrophils are cleared from sites of infection by macrophages.

F) A) and E)
G) A) and D)

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An example of an antimicrobial peptide that protects epithelial surfaces from pathogens is _____.


A) glycoprotein
B) defensin
C) proteoglycan
D) lysozyme
E) sebum.

F) C) and E)
G) A) and D)

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The _____ is (are) the lymphoid organ(s) that filter(s) the blood.


A) spleen
B) tonsils
C) Peyer's patches
D) appendix
E) adenoids.

F) A) and B)
G) A) and E)

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A.Identify the two major progenitor subsets of leukocytes. B.Where do they originate in adults? C.Name the white blood cells that differentiate from these two progenitor lineages.

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A.The two major progenitor subsets of le...

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The thin layer of cells that makes up the interior lining of the blood vessels is called the _____.


A) mucosa
B) epithelium
C) endothelium
D) connective tissue
E) lymphoid tissue.

F) A) and B)
G) A) and D)

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What are clonal selection and clonal expansion in the context of an adaptive immune response? Describe how they shape the adaptive immune response.

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In an adaptive immune response to a path...

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Which of the following pairs is mismatched?


A) monocyte progenitor: macrophage
B) erythroid progenitor: megakaryocyte
C) myeloid progenitor: neutrophil
D) lymphoid progenitor: natural killer cell.
E) None of the above is mismatched.

F) B) and C)
G) D) and E)

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A bacterium that causes a common disease in a population that has been previously exposed to it is called _____.


A) opportunistic
B) resistant
C) commensal
D) endemic
E) attenuated.

F) B) and C)
G) C) and E)

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The spleen differs from other secondary lymphoid organs in which of the following ways?


A) It does not contain T cells.
B) It filters blood as well as lymph.
C) It is populated by specialized cells called M cells.
D) It receives pathogens via afferent lymphatic vessels.
E) It has no connection with the lymphatics.

F) A) and E)
G) A) and D)

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Describe the characteristics commonly associated with inflammation and what causes them.

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The hallmarks of inflammation are heat,r...

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The first line of defense against microorganisms that infect the body is referred to as _____.


A) opportunistic immunity
B) innate immunity
C) adaptive immunity
D) primary immunity
E) central immunity.

F) B) and C)
G) A) and E)

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