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Which type of lymphocyte is sometimes called a "killer cell" because it brings about destruction of cells bearing a specific non-cell protein?


A) helper T cell
B) suppressor T cell
C) cytotoxic T cell
D) memory T cell
E) macrophage

F) A) and B)
G) A) and C)

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In the later 1800s, the brilliant French chemist Louis Pasteur worked with chicken cholera, passing the disease agent from sick to healthy chickens. He suspended his research and went on vacation for several weeks. When he returned, the old cholera culture he gave to healthy chickens failed to kill them. He assumed his culture was bad and injected these same chickens with a fresh culture of chicken cholera. These chickens remained healthy while new chickens injected with the fresh culture of chicken cholera rapidly became sick and died. From our current knowledge of immunity, how would these observations be explained?


A) Pasteur had accidentally discovered a strain of chickens that had natural immunity.
B) His first disease culture had weakened over time and stimulated the development of active immunity.
C) His first disease culture had weakened over time and the chickens developed a form of passive immunity.
D) The chickens apparently had better B cells for development of more effective antibodies.
E) The first set of chickens served as a control group to the second set that showed the development of antibodies.

F) A) and B)
G) A) and C)

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Which lymphoid organ has stem cells that are capable of dividing and producing blood cells?


A) thymus
B) lymph nodes
C) spleen
D) bone marrow

E) All of the above
F) A) and B)

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A cell that produces a rapid antibody response against a foreign protein when it is encountered years after the first encounter is a(n)


A) memory B cell.
B) memory T cell.
C) cytotoxic T cell.
D) plasma cell.
E) antigen-presenting cell.

F) B) and E)
G) None of the above

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Disease-causing agents like viruses or bacteria are considered a(n)


A) antibody.
B) vaccine.
C) thrombin.
D) allergen.
E) pathogen.

F) A) and E)
G) A) and C)

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Inflammation or the inflammatory response is a harmful process that should be avoided.

A) True
B) False

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Anaphylactic shock may occur due to


A) exposure to the HIV virus.
B) a bee sting.
C) organ donation.
D) use of interferon.
E) antihistamines.

F) A) and E)
G) B) and E)

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If you are bitten by a highly venomous snake, you would need to be given antivenom right away. Antivenom is made from injecting horses with small-to-larger dosages of snake venom, and then harvesting the antibodies from the horse plasma. Antivenom is an example of


A) passive immunity.
B) active immunity.
C) developing an inflammatory response to increase the IgG production.
D) high levels of complement.
E) high levels of interferon.

F) A) and E)
G) A) and D)

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An antihistamine counters the effects of histamine. Which of the following is an effect of histamine?


A) Increased blood flow brings more white blood cells to the site of injury or invasion.
B) Capillary dilation increases blood flow and causes surface redness.
C) Increased blood flow and permeability increase the fluids in the tissues, causing them to swell.
D) Increased blood flow brings more warmth to the area, causing a local "fever" that helps white blood cells and suppresses microbes.
E) All of the answer choices are effects of histamine.

F) B) and D)
G) A) and E)

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Would untreated SCID be considered a lethal disease?

A) True
B) False

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The larger lymphatic vessels are most similar in structure to


A) arteries.
B) veins.
C) capillaries.
D) intestinal villi.
E) nephron.

F) C) and E)
G) B) and C)

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Which of the following statements is true about hemolytic disease of the newborn?


A) Hemolytic disease of the newborn occurs when the father is Rh- and the mother is Rh+.
B) Hemolytic disease of the newborn would be a problem any time the mother is Rh-, regardless of the father's blood type.
C) Hemolytic disease of the newborn occurs when a Rh- mother and a Rh+ father produce an Rh+ child.
D) If a mother has a higher threshold for rejecting foreign tissues there is a higher chance of the baby having hemolytic newborn disease.
E) The problem is complicated because the disease is dependent on both Rh factor and ABO blood groups.

F) C) and D)
G) All of the above

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Which blood cells are usually the first to arrive at the site of an infection?


A) neutrophils
B) natural killer cells
C) red blood cells
D) interferons
E) monocytes

F) A) and C)
G) A) and E)

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Edema results from


A) accumulation of tissue fluid.
B) an abnormally high amount of plasma proteins.
C) the kidney excreting too little protein.
D) drinking too little water.
E) drinking more water than normal.

F) C) and D)
G) A) and E)

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Which type of T cell has a TCR that can recognize an antigen fragment presented by antigen-presenting cells with MHC class II proteins?


A) helper T cells
B) cytotoxic T cells
C) major histocompatibility complex
D) B cells
E) monocytes

F) A) and B)
G) A) and E)

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Earlier in the history of Western medicine, surgeons did not know the immune function of the thymus gland and it was sometimes removed in children. What symptoms would you predict these patients might display after having their thymus gland removed?


A) increased inflammatory and allergic responses to foreign material including viruses
B) reduced ability to recognize foreign material and distinguish it from body proteins
C) serious problems after receiving blood transfusions of any type of blood
D) complete rejection of all normal body tissues
E) failure to produce any white blood cells

F) B) and E)
G) A) and B)

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An autoimmune disease means that the body attacks itself because it does not recognize itself.

A) True
B) False

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Which of the following organs has a function independent of the others?


A) bone marrow
B) thymus
C) spleen
D) lymph nodes
E) kidneys

F) A) and E)
G) B) and E)

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A vaccine contains


A) penicillin.
B) horse serum.
C) antigens that are no longer virulent.
D) antibodies made by plasma cells.
E) antibiotics against a particular bacterial strain.

F) A) and B)
G) None of the above

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A response that does not occur immediately cannot be considered an allergic response, even if it appears like one.

A) True
B) False

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