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If 14% of the nucleotides from a DNA molecule contain the base T,what percent will contain the base G?


A) 14%
B) 18%
C) 28%
D) 36%
E) 72%

F) B) and C)
G) A) and B)

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The lagging strand is replicated with a series of Okazaki fragments and that is why its synthesis is considered to be


A) discontinuous.
B) continuous.
C) bidirectional.
D) antiparallel.
E) semiconservative.

F) C) and D)
G) B) and D)

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Which statement about the Hershey-Chase experiment is false?


A) DNA was labeled with radioactive phosphorus.
B) Protein was labeled with radioactive sulfur.
C) The virus-infected bacteria contained radioactive phosphorus.
D) The virus-infected bacteria contained radioactive sulfur.

E) None of the above
F) All of the above

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As the two strands of DNA are unraveled,which enzyme relieves the strain on the two strands?


A) DNA polymerase
B) DNA ligase
C) DNA gyrase
D) DNA endonuclease
E) DNA exonuclease

F) C) and E)
G) D) and E)

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If 16% of the nucleotides in one strand of a DNA molecule contain the base G,what percent of the nucleotides on the complementary strand will also contain the base G?


A) 16%
B) 8%
C) 34%
D) 32%
E) It is impossible to determine from the information given.

F) B) and C)
G) B) and D)

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Who provided X-ray diffraction photographs of purified DNA fibers that suggested a helical structure with a consistent diameter of about 2 nm and a complete helical turn every 3.4 nm?


A) Hershey and Chase
B) Chargaff
C) Franklin
D) Watson and Crick

E) None of the above
F) A) and D)

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DNA consists of two antiparallel strands of nucleotides held together by


A) peptide bonds.
B) covalent bonds.
C) ionic bonds.
D) hydrogen bonds.

E) None of the above
F) B) and C)

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When a mixture of live nonvirulent bacteria and dead virulent bacteria was injected into mice,Griffith unexpectedly found that the injected mice died.He explained this result by suggesting that the nonvirulent bacteria are being


A) activated.
B) transformed.
C) translated.
D) transcribed.
E) expressed.

F) A) and C)
G) A) and D)

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The two strands of a DNA molecule contain nitrogen bases which are


A) identical.
B) parallel.
C) complementary.
D) proportionate.
E) random.

F) B) and E)
G) All of the above

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During DNA replication,which enzyme removes the RNA primers and then fills in the gap?


A) DNA pol I
B) DNA primase
C) DNA pol III
D) DNA ligase

E) A) and B)
F) A) and C)

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Who proposed that the structure of DNA is a double helix with two polynucleotide chains running in opposite directions and held together by hydrogen bonding between pairs of nitrogenous bases?


A) Hershey and Chase
B) Chargaff
C) Franklin
D) Watson and Crick
E) Meselson and Stahl

F) B) and E)
G) A) and B)

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The site where the two original DNA strands separate and active replication occurs is called the


A) replication fork.
B) replisome.
C) primosome.
D) lagging strand.
E) sliding clamp subunit.

F) B) and D)
G) A) and E)

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What is the correct sequence for DNA replication in E.coli?


A) initiation,termination,elongation
B) initiation,elongation,termination
C) elongation,termination,initiation
D) elongation,initiation,termination

E) All of the above
F) A) and B)

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DNA primase


A) creates a short RNA primer that is complementary to an RNA template.
B) creates a short DNA primer that is complementary to an RNA template.
C) creates a short DNA primer that is complementary to a DNA template.
D) creates a short DNA template that is complementary to an RNA primer.
E) creates a short RNA primer that is complementary to a DNA template.

F) A) and E)
G) B) and C)

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In Griffith's experiments,


A) mice infected with live nonvirulent bacteria developed pneumonia and died.
B) nonvirulent bacteria transformed the virulent bacteria into a nonvirulent variety.
C) mice infected with heat-killed virulent bacteria and live nonvirulent bacteria developed pneumonia and died.
D) mice infected with heat-killed virulent bacteria and heat-killed nonvirulent bacteria developed pneumonia and died.

E) All of the above
F) None of the above

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In which cells would you expect to find the highest level of telomerase?


A) muscle cells
B) adipose tissue cells
C) neurons
D) cells that replenish the lining of the gut

E) A) and C)
F) B) and C)

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You decide to repeat the Meselson-Stahl experiment,except this time you plan to grow the E.coli cells on light 14N medium for many generations and then transfer them to heavy 15N medium and allow them to grow for 2 additional generations (2 rounds of DNA replication) .If the semiconservative model of DNA replication is correct,what is the expected distribution of DNA in the density gradient after two rounds of replication?


A) One band of intermediate density.
B) One band of intermediate density and one band of light density.
C) One band of intermediate density and one band of heavy density.
D) One band of heavy density and one band of light density.
E) One band of heavy density.

F) B) and E)
G) B) and D)

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During DNA replication,DNA pol III synthesizes the lagging strand in segments,called


A) replication fragments.
B) Chargaff's segments.
C) repeating primers.
D) replisomes.
E) Okazaki fragments.

F) A) and B)
G) A) and C)

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Avery and his coworkers showed that the agent responsible for changing nonvirulent bacteria into virulent bacteria was


A) protein.
B) polysaccharide.
C) DNA.
D) RNA.
E) lipid.

F) B) and E)
G) All of the above

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Chargaff's rules for the pairing of nitrogen bases is


A) A = C and G = T.
B) A = T and G = C.
C) A = G and C = T.
D) A+T = G+C.

E) A) and B)
F) None of the above

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