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Your friend is having difficulty keeping track of the energy flow from glucose through glycolysis,the Citric acid cycle and electron transport.Your best advice would be to


A) follow ATP production.
B) follow the protons.
C) follow NAD+ production.
D) follow the electrons.

E) A) and D)
F) B) and D)

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What aspect of cellular respiration occurs in the cytoplasm in eukaryotic cells?


A) Glycolysis
B) Pyruvate oxidation
C) The Citric acid cycle
D) The electron transport chain
E) ATP synthesis

F) B) and D)
G) B) and C)

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Aerobic respiration involves the transfer of many electrons from glucose to electron carriers such as NAD+ over a series of multiple steps.Ultimately though,it is the reaction of glucose with oxygen to generate carbon dioxide,water and energy.Why doesn't glucose react directly with oxygen in cells?


A) Oxygen cannot accept electrons,and thus an electron carrier like NAD+ is needed.
B) Oxygen and glucose are localized in different subcellular compartments.
C) The direct reaction of oxygen with glucose would be extremely destructive to cells.
D) The reaction of oxygen with glucose is not spontaneous.

E) B) and C)
F) C) and D)

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Why is the energy generated from the catabolism of sugars and other macromolecules ultimately harnessed to generate ATP?


A) ATP can be used by cells to drive endergonic reactions
B) ATP can be used to make RNA,which is an energy storage molecule in the cell
C) ATP synthesis is an exergonic reaction
D) ATP is required to generate the proton gradient in the intermembrane space of mitochondria

E) None of the above
F) All of the above

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When oxygen is unavailable during heavy exercise what process do muscle cells use for energy generation?


A) Glycolysis coupled with alcohol fermentation
B) Anaerobic respiration
C) Aerobic respiration
D) Glycolysis coupled with lactate fermentation

E) All of the above
F) C) and D)

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Phosphofructokinase is regulated by a number of factors,including high levels of ATP.Why is this enzyme regulated by ATP levels?


A) If ATP levels are high,this provides a mechanism to directly inhibit the Citric acid cycle,thus preventing further generation of NADH,FADH2 and ATP molecules that are not needed.
B) If ATP levels are high,it is important to directly inhibit the reaction that commits the substrate to glycolysis to allow the substrate to be available for other reactions,since the cell has ample energy.
C) If ATP levels are high,it is important to inhibit ATP synthase,and phosphofructokinase directly inhibits ATP synthase.
D) If ATP levels are high,this provides a mechanism to directly inhibit the electron transport chain,thus preventing the formation of a proton gradient in the intermembrane space of mitochondria.

E) A) and D)
F) All of the above

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In order to lose weight and reduce body fat,a friend of yours has decided to eliminate all fat from his diet,while consuming unrestricted amounts of carbohydrates.What do you think of this idea?


A) It is a good idea,because if your friend doesn't eat any fat,he cannot store any additional fat.
B) It is a bad idea,because consumption of fat is required to provide cofactors for the electron transport chain.
C) It is a good idea,because under conditions where ATP levels are low in cells,carbohydrates will be stored,and fat stores will be catabolized via beta-oxidation to generate energy.
D) It is a bad idea,because if ATP levels are high in cells,excess acetyl-CoA from the metabolism of carbohydrates can be used for fatty acid synthesis.

E) B) and C)
F) C) and D)

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What stage of cellular respiration can occur in human cells with or without oxygen present?


A) The Citric acid cycle
B) Glycolysis
C) The electron transport chain
D) Pyruvate oxidation

E) A) and B)
F) A) and C)

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What molecule can oxidize NADH?


A) Acetaldehyde
B) Lactate
C) Ubiquinone
D) Glucose
E) Isocitrate

F) All of the above
G) A) and B)

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Glucose is not our only food source,nor the only one we can utilize in our bodies to generate energy.Other primary sources of energy include other sugars,proteins,and fats.What metabolic intermediate are fats primarily converted into?


A) Pyruvate
B) Acetyl-CoA
C) Citric acid cycle intermediates
D) Electron transport chain components
E) ATP Synthase

F) B) and E)
G) B) and D)

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All of the reactions of cellular respiration that occur after glycolysis take place in what part of the eukaryotic cell?


A) The chloroplast
B) The nucleus
C) The mitochondria
D) The plasma membrane
E) The cytoplasm

F) All of the above
G) C) and D)

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C

If you take into account the amount of ATP generated by ATP synthase per molecule of NADH and per molecule of FADH2 produced,and the number of ATP molecules produced by substrate-level phosphorylation,what is the predicted energy yield of the Citric acid cycle,per molecule of glucose in eukaryotic cells?


A) 18 ATP
B) 2 ATP
C) 10 ATP
D) 20 ATP
E) 30 ATP

F) A) and B)
G) A) and E)

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What is the oxidized form of the most common electron carrier that is needed for both glycolysis and the Citric acid cycle?


A) ATP
B) FAD
C) pyruvate
D) NAD+
E) acetyl-CoA

F) None of the above
G) C) and D)

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This process is common to all living cells:


A) Glycolysis
B) Alcohol fermentation
C) The Citric acid cycle
D) Electron transport chain reactions
E) Pyruvate oxidation

F) All of the above
G) None of the above

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Pyruvate oxidation in eukaryotic cells occurs in the ________.


A) cytoplasm
B) nucleus
C) Golgi body
D) mitochondria
E) plasma membrane

F) A) and C)
G) None of the above

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What is an end-product of glycolysis?


A) Oxaloacetate
B) NAD+
C) Alcohol
D) ADP
E) Pyruvate

F) A) and D)
G) All of the above

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What is the net number of ATP generated directly during glycolysis per molecule of glucose?


A) 0
B) 2
C) 4
D) 6
E) 8

F) A) and E)
G) B) and C)

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B

The energy released in the mitochondrial electron transport chain is used to transport protons into the


A) mitochondrial matrix.
B) cytoplasm.
C) endoplasmic reticulum.
D) intermembrane space of the mitochondria.
E) nucleus.

F) B) and E)
G) C) and D)

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Arsenic poisoning can lead to organ failure and death.Though arsenic can inhibit or interfere with a number of cellular enzymes,arsenic poisoning is thought to be mainly due to indirect inhibition of enzymes involved in both pyruvate oxidation and the Citric acid cycle.As a result,this compound must be able to enter which cellular compartment?


A) The cytoplasm
B) The nucleus
C) The intermembrane space of the mitochondria
D) The mitochondrial matrix
E) The endoplasmic reticulum

F) B) and E)
G) A) and C)

Correct Answer

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If ATP synthase had a mutation in the F1 complex portion of the protein,which function of ATP synthase would most likely be affected?


A) The rotation of the rotor
B) The flow of protons through the channel
C) The conversion of ADP and Pi to ATP
D) The insertion of the enzyme into the membrane

E) C) and D)
F) A) and B)

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C

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