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The hyperpolarization that occurs at the end of an action potential is due to the prolonged


A) open state of voltage-gated sodium channels.
B) closure of chemically gated sodium channels.
C) open state of voltage-gated potassium channels.
D) closure of voltage-gated potassium channels.
E) open state of chemically gated sodium channels.

F) B) and C)
G) A) and E)

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The primary inhibitory neurotransmitter in the brain is


A) glutamate.
B) valine.
C) GABA.
D) serotonin.
E) serine.

F) B) and C)
G) C) and D)

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Typically, the resting membrane potential of a neuron is


A) 7 V.
B) 700 mV.
C) −7 V.
D) −70 mV.
E) 0 mV.

F) B) and C)
G) C) and E)

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Which statement accurately compares the transmission speed of the different types of synapses?


A) Transmission at chemical synapses involves a brief synaptic delay, but electrical synapses are faster.
B) Transmission at both chemical and electrical synapses involves a synaptic delay of approximately 1 millisecond.
C) Transmission at electrical synapses involves a brief synaptic delay, but chemical synapses are faster.
D) Electrical synapses have a constant delay of 1 millisecond, but chemical synaptic delays vary between 0.1 and 0.3 millisecond.

E) B) and D)
F) All of the above

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Select all the features you would expect in a nerve fiber that conducted signals slowly, such as those that control gastric secretions and other functions that are not urgent. A) Small diameter B) Unmyelinated C) Large diameter D) Myelinated

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The size of an EPSP is independent of the amount of excitatory neurotransmitter that is released by the presynaptic cell.

A) True
B) False

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Electrical synapses involve coupling of neurons by


A) synaptic clefts.
B) desmosomes.
C) gap junctions.
D) satellite cells.

E) C) and D)
F) All of the above

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Action potentials are generated by the opening of ________ gated channels and they occur on the ________.


A) voltage-, axon
B) voltage-, dendrite
C) chemically, axon
D) chemically, dendrite

E) A) and C)
F) All of the above

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Receptors are parts of the nervous system that allow it to


A) initiate responses to information.
B) process information.
C) collect information.
D) conduct impulses to muscles.

E) B) and C)
F) A) and C)

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If there were no sodium leak channels, the resting membrane potential of a neuron would be


A) more negative.
B) more positive.
C) the same.
D) 0 mV.

E) A) and B)
F) A) and C)

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Arrival of an action potential at the synaptic knob results in


A) opening of voltage-gated calcium channels and diffusion of calcium into the synaptic knob.
B) opening of voltage-gated calcium channels and diffusion of calcium out of the synaptic knob to the interstitial fluid.
C) closure of voltage-gated calcium channels in the synaptic knob membrane.
D) opening of chemically gated calcium channels and diffusion of calcium into the synaptic knob.
E) opening of chemically gated calcium channels and diffusion of calcium out of the synaptic knob to the interstitial fluid.

F) A) and B)
G) A) and D)

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Wallerian degeneration involves the breakdown of


A) the segments of axon and myelin sheath between the site of damage and the peripheral effector.
B) the segments of axon and myelin sheath between the site of damage and the cell body.
C) the neurilemma both central and peripheral to the site of trauma.
D) macrophages and microglia that have completed the job of CNS cleanup after trauma.

E) All of the above
F) A) and B)

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Which is not characteristic of neurons?


A) High mitotic rate
B) High metabolic rate
C) Require continuous supplies of glucose and oxygen
D) Extreme longevity
E) No exceptions; all of these are characteristic of neurons.

F) A) and B)
G) A) and E)

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A mixed nerve is one that contains both


A) cranial and spinal nerve fibers.
B) sensory and motor neurons.
C) unipolar and bipolar neurons.
D) an endoneurium and an epineurium.
E) presynaptic and postsynaptic neurons.

F) A) and E)
G) B) and D)

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The type of neuronal circuit that spreads information from one presynaptic neuron to several postsynaptic neurons is a ________ circuit.


A) converging
B) diverging
C) reverberating
D) parallel-after-discharge
E) None of the choices is correct.

F) D) and E)
G) B) and E)

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Which is not a function of the motor division of the nervous system?


A) Conducts impulses from the CNS
B) Transmits impulses to muscles and glands
C) Transmits impulses from the viscera
D) Voluntary control of skeletal muscle
E) Involuntary control of the heart

F) All of the above
G) A) and C)

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The main way acetylcholine is cleared from a synapse is by


A) degradation by an enzyme.
B) uptake by the postsynaptic cell.
C) reuptake by the presynaptic cell.
D) being engulfed by a supporting glial cell.

E) A) and D)
F) A) and C)

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Endocannabinoids are neuromodulators that decrease neurotransmitter release from presynaptic neurons.

A) True
B) False

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The glial cell that myelinates and insulates axons within the CNS is the


A) astrocyte.
B) ependymal cell.
C) neurolemmocyte.
D) microglial cell.
E) oligodendrocyte.

F) A) and B)
G) All of the above

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The glial cell with the responsibility of occupying the space left by dead or dying neurons is the


A) astrocyte.
B) ependymal cell.
C) neurolemmocyte.
D) microglial cell.
E) oligodendrocyte.

F) B) and E)
G) B) and C)

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