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Ultimately, the signal from a peptide hormone is typically conveyed to the effectors in the cell via the transfer of what molecular moiety?


A) nucleotide
B) NO (nitric oxide)
C) H2O
D) phosphate group

E) A) and C)
F) B) and D)

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What is a primary function of growth hormone?


A) initiates stress response
B) raises blood glucose level
C) lowers blood glucose level
D) stimulates bone growth

E) B) and C)
F) A) and D)

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True or False: The brain controls organ system function only through direct contact with sympathetic or parasympathetic nerves.

A) True
B) False

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Choose the hormone that is NOT correctly matched with its chemical category.


A) polypeptides-ADH
B) steroid-estradiol
C) amine-FSH
D) glycoprotein-LH

E) A) and B)
F) A) and C)

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If blood transports hormones throughout the body, how do they communicate with specific targets?


A) Special gateway valves in the blood vessels direct hormones to their target tissues.
B) Special carrier proteins "walk" along microtubule tracts to deliver the hormones to their targets.
C) Axonal pathfinding mediates the delivery of hormones to their specific targets.
D) Only target tissues have receptors that allow them to receive the signal.

E) A) and B)
F) A) and C)

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There is a molecule in black licorice that inhibits an enzyme which normally limits activation of mineralocorticoid receptors.Thus, overconsumption of licorice can mimic the effect of excess aldosterone.What would be the result?


A) infertility in men
B) hypertension (high blood pressure) due to insufficient potassium in the blood
C) excessive body hair
D) low blood pressure due to excessive potassium in the blood

E) A) and C)
F) C) and D)

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Which of the following hormones regulates metamorphosis and molting in insects?


A) melatonin
B) ecdysone
C) estrogen
D) somatostatin

E) A) and C)
F) B) and C)

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Your doctor returns with your lab results and looks grave."I'm afraid," she says, "you seem to have a problem with your hypophysis." What do you say?


A) "Doctor, right now I'm interested in results, not testable ideas about how things work!"
B) "Well, that's only responsible for one or two hormones, so it should be easy to treat."
C) "Am I going to need insulin shots?"
D) "Is it the posterior? Neurological problems run in my family."

E) B) and D)
F) B) and C)

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What lab tests would you order to find the source of the problem?


A) cortisol, LH, and FSH
B) None -- the birth control pills include corticosteroid hormones.She should switch to another form of birth control.
C) cortisol, ACTH, and CRH
D) cortisol and ACTH

E) A) and B)
F) None of the above

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A ______ is a regulatory molecule that is secreted into the blood by an endocrine gland.


A) metabolite
B) hormone
C) peptide
D) G protein

E) A) and B)
F) All of the above

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Which statement does NOT correctly describe hormones that can directly enter a cell?


A) Steroid hormones can enter directly into cells because of their hydrophobic makeup.
B) Water-soluble hormones can enter directly into cells because of their nonpolar makeup.
C) Steroid hormones dissolve poorly in the plasma and are transported to target cells via special protein carriers.
D) Once these hormones enter a cell, they bind to a cytoplasmic receptor and travel as a complex to the nucleus, or they may bind to the receptor after entering the nucleus.

E) A) and B)
F) A) and C)

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Your cat has fleas! You look at the ingredients in the flea control ointment, and see that it contains methoprene, a juvenile hormone analog.What does this accomplish?


A) prevents flea larvae from maturing
B) kills juvenile fleas
C) reinvigorates the cat's immune system, to repel the fleas
D) forces juvenile fleas to mature early, disrupting development of reproductive organs

E) A) and C)
F) A) and D)

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Which hormone helps with adaptation to long term stress?


A) glucocorticoids
B) epinephrine
C) insulin
D) glucagon

E) A) and D)
F) All of the above

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Which of the following hormones exerts its action by interacting with a receptor at the cell surface?


A) insulin
B) cortisol
C) testosterone
D) estrogen

E) A) and D)
F) A) and B)

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A middle-aged female patient complains of changes to her face.Her cheekbones and eyebrows have become more prominent, and her jaw is growing.You suspect acromegaly, a disorder caused by excessive growth hormone.She had no growth abnormalities in her youth.What do you suspect is the most likely cause of her problem?


A) a tumour of the pineal gland
B) congenital mutation of the GH regulatory region
C) a tumour of the anterior pituitary
D) a tumour of the posterior pituitary

E) C) and D)
F) A) and D)

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Ecdysone and juvenile hormone regulate molting and ____________ in insects.


A) metamorphosis
B) sexual behavior
C) body shape
D) egg production

E) C) and D)
F) A) and B)

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Which is NOT an effect of the hormonal products of the adrenal medulla?


A) accelerate heartbeat
B) stimulate synthesis of glycogen
C) increase blood pressure
D) reduce blood flow to the skin and digestive organs

E) All of the above
F) C) and D)

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Beta-blockers are a class of drugs that target beta-adrenergic receptors, blocking the action of epinephrine and norepinephrine.These drugs are used to treat heart conditions, hypertension, glaucoma, and migraine headaches and are also used off-label to alleviate stage fright in performers.Since the beta-adrenergic receptor is a GPCR, what intracellular event is prevented by the use of a beta-blocker?


A) a protein kinase cascade, initiated by the receptor's intracellular kinase domain
B) release of an activated G protein subunit bound to GTP
C) transport of the receptor-hormone complex into the cell and the nucleus, where it would regulate transcription
D) a protein phosphatase cascade, initiated by the receptor's intracellular phosphatase domain

E) None of the above
F) B) and D)

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Your general practitioner considers your unusual set of symptoms, and says, "You seem to have a problem with maintaining homeostasis in your body." Which type of specialist might the doctor refer you to? (Check two.) _____ hematologist __X__ endocrinologist __X__ neurologist _____ osteologist _____ opthamologist _____ obstetrician-gynecologist

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What do you already know about homeostas...

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Women often receive synthetic oxytocin to induce childbirth or augment contractions.What is an important consideration about the use of synthetic oxytocin?


A) It is impossible to mimic its chemical structure, so it may act on other receptors and cause side effects.
B) The synthetic form does not travel down motor neurons, so it is less effective than the natural form.
C) It can be difficult to get the levels just right, so uterine contractions can be too strong.
D) If you fail to simultaneously provide synthetic G protein, the hormone is ineffective.

E) A) and C)
F) All of the above

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