Question 1

If a mutation prevented synthesis of the beta subunit of DNA pol III, which would be most affected?

Accepted Answer

A)  DNA unwinding
B)  formation of RNA primers
C)  formation of the replication fork
D)  processivityE) B) and C)
F) A) and C)

Question 2

The two strands of a DNA molecule contain nitrogen bases which are

Accepted Answer

A)  identical.
B)  parallel.
C)  complementary.
D)  proportionate.E) A) and D)
F) None of the above

Question 3

What is the correct sequence for DNA replication in

Accepted Answer

A)  initiation, termination, elongation
B)  initiation, elongation, termination
C)  elongation, termination, initiation
D)  elongation, initiation, terminationE) A) and D)
F) None of the above

Question 4

Which statement about the Hershey-Chase experiment is false?

Accepted Answer

A)  DNA was labeled with radioactive phosphorus.
B)  Protein was labeled with radioactive sulfur.
C)  The virus-infected bacteria contained radioactive phosphorus.
D)  The virus-infected bacteria contained radioactive sulfur.E) B) and C)
F) A) and C)

Question 5

You are asked to participate in a clinical trial for a new drug that can activate telomerase.Which of the following is a likely risk of such a drug?

Accepted Answer

A)  decreased capacity for tissue repair
B)  increased vulnerability to cancer
C)  premature aging
D)  decreased telomere lengthE) B) and D)
F) B) and C)

Question 6

After attaching to a bacterial cell, a bacteriophage typically

Accepted Answer

A)  injects protein into the cell.
B)  extracts protein from the cell.
C)  injects DNA into the cell.
D)  extracts DNA from the cell.E) B) and D)
F) A) and B)

Question 7

Replication of DNA is

Accepted Answer

A)  conservative.
B)  redundant.
C)  dispersive.
D)  semiconservative.E) None of the above
F) A) and D)

Question 8

Which of the following DNA sequences is complementary to 5' ATGGTCAGT 3'?

Accepted Answer

A)  5' ATGGTCAGT 3'
B)  5' TGACTGGTA 3'
C)  5' TACCAGTCA 3'
D)  5' ACTGACCAT 3'E) None of the above
F) A) and B)

Question 9

The lagging strand is replicated with a series of Okazaki fragments and that is why its synthesis is considered to be

Accepted Answer

A)  discontinuous.
B)  continuous.
C)  bidirectional.
D)  antiparallel.E) A) and B)
F) B) and C)

Question 10

During DNA replication, which enzyme removes the RNA primers and then fills in the gap?

Accepted Answer

A)  DNA pol I
B)  DNA primase
C)  DNA pol III
D)  DNA ligaseE) All of the above
F) C) and D)

Question 11

Viruses that attack bacteria are called

Accepted Answer

A)  phages
B)  proviruses
C)  virulent
D)  lyticE) A) and B)
F) B) and D)

Question 12

If a mutation produced helicase that was unable to hydrolyze ATP, DNA replication would be

Accepted Answer

A)  stopped.
B)  speeded up.
C)  unaffected.
D)  more prone to errors.E) All of the above
F) A) and C)

Question 13

Why does DNA pol I carry the number one?

Accepted Answer

A)  It was the first polymerase isolated from
B)  It is the first polymerase to be activated during DNA replication.
C)  It is the only polymerase that has both 3' to 5' and 5' to 3' exonuclease activity.
D)  It is the smallest polymerase.E) B) and C)
F) A) and C)

Question 14

In which cells would you expect to find the highest level of telomerase?

Accepted Answer

A)  muscle cells
B)  adipose tissue cells
C)  neurons
D)  cells that replenish the lining of the gutE) A) and B)
F) C) and D)

Question 15

Because the two strands of a DNA molecule are ________ to each other, either one can be used as a template to reconstruct the other.

Accepted Answer

A)  identical
B)  antiparallel
C)  bound
D)  complementaryE) A) and B)
F) A) and C)

Question 16

Nucleotides have a phosphate group attached at the ___ carbon atom of the sugar.

Accepted Answer

A)  2'
B)  3'
C)  5'
D)  1'E) B) and D)
F) C) and D)

Question 17

The double helix model of DNA structure was proposed by

Accepted Answer

A)  Watson and Crick.
B)  Griffith.
C)  Avery.
D)  Franklin.E) B) and C)
F) C) and D)

Question 18

Suppose a new species of bacterium is discovered.It contains a form of DNA pol III that can add new nucleotides to either the 5' end or the 3' end of an existing strand.All other properties of the enzyme remain unchanged.How would DNA replication in these bacteria differ from normal replication?

Accepted Answer

A)  Both new strands could be synthesized continuously like the leading strand.
B)  The same polymerase molecule could synthesize both strands at the same time.
C)  Helicase would no longer be required for replication.
D)  DNA gyrase would no longer be required for replication.E) A) and B)
F) C) and D)

Question 19

Who originally discovered the process of bacterial transformation?

Accepted Answer

A)  Watson and Crick
B)  Chargaff
C)  Hershey and Chase
D)  GriffithE) A) and B)
F) B) and D)

Question 20

Eukaryotic organisms speed up the process of DNA replication by

Accepted Answer

A)  shortening the initiation phase.
B)  producing several sliding clamp complexes which provide more binding sites for DNA pol III.
C)  using DNA gyrase to unravel the double helix rather than DNA helicase.
D)  using multiple origins of replication on each chromosome.E) C) and D)
F) None of the above

Exam 14: Dna: the Genetic Material

The double helix model of DNA structure was proposed by

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Replication of DNA is

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Who originally discovered the process of bacterial transformation?

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Why does DNA pol I carry the number one?

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Suppose a new species of bacterium is discovered.It contains a form of DNA pol III that can add new nucleotides to either the 5' end or the 3' end of an existing strand.All other properties of the enzyme remain unchanged.How would DNA replication in these bacteria differ from normal replication?

Correct AnswerverifiedShow Answer

Eukaryotic organisms speed up the process of DNA replication by

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If a mutation produced helicase that was unable to hydrolyze ATP, DNA replication would be

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The lagging strand is replicated with a series of Okazaki fragments and that is why its synthesis is considered to be

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Which statement about the Hershey-Chase experiment is false?

Correct AnswerverifiedShow Answer

During DNA replication, which enzyme removes the RNA primers and then fills in the gap?

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Which of the following DNA sequences is complementary to 5' ATGGTCAGT 3'?

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Because the two strands of a DNA molecule are ________ to each other, either one can be used as a template to reconstruct the other.

Correct AnswerverifiedShow Answer

Nucleotides have a phosphate group attached at the ___ carbon atom of the sugar.

Correct AnswerverifiedShow Answer

The two strands of a DNA molecule contain nitrogen bases which are

Correct AnswerverifiedShow Answer

You are asked to participate in a clinical trial for a new drug that can activate telomerase.Which of the following is a likely risk of such a drug?

Correct AnswerverifiedShow Answer

What is the correct sequence for DNA replication in

Correct AnswerverifiedShow Answer

If a mutation prevented synthesis of the beta subunit of DNA pol III, which would be most affected?

Correct AnswerverifiedShow Answer

Viruses that attack bacteria are called

Correct AnswerverifiedShow Answer

In which cells would you expect to find the highest level of telomerase?

Correct AnswerverifiedShow Answer

After attaching to a bacterial cell, a bacteriophage typically

Correct AnswerverifiedShow Answer

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