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Which of the following muscle types has the slowest contraction time?


A) fast oxidative skeletal muscle
B) cardiac muscle
C) slow oxidative skeletal muscle
D) smooth muscle
E) fast glycolytic skeletal muscle

F) C) and D)
G) A) and B)

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Which of the following mechanisms does NOT account for the decrease in force development by muscle cells during sustained force development?


A) Repeated action potentials along the same neuron can lead to neuromuscular fatigue.
B) Compression of muscle during contraction can reduce blood flow to the muscle.
C) The crossbridges can become resistant to ATP.
D) Glycolytic fibers produce lactic acid and inhibit enzyme activity with their hydrogen ion.
E) Oxidative fibers can be depleted of glycogen, their primary energy source.

F) C) and D)
G) A) and B)

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Which of the following stores calcium to be released for muscle contraction?


A) sarcomeres
B) actin and myosin
C) motor end plate
D) sarcoplasmic reticulum
E) tendons

F) All of the above
G) B) and E)

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Which protein binds calcium in smooth muscle cells?


A) tropomyosin
B) myosin light -chain kinase
C) troponin
D) calmodulin
E) titin

F) C) and D)
G) B) and D)

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In smooth muscle, the structures analogous to Z lines in skeletal muscle are called


A) MLCK.
B) gap junctions.
C) intercalated disks.
D) dense bodies.
E) S lines.

F) B) and E)
G) B) and D)

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  -What is the structure indicated by the number 1 in Figure 12.1 and what is its functional significance A)  A band : length of myosin attached to an M line B)  H zone : area of myosin not overlapped by actin C)  Z line : anchors the thin filaments together D)  M line : where the tails of the myosin molecules are bound to one another E)  sarcomere : the functional unit of muscle contraction whose length is changed as a muscle shortens and lengthens -What is the structure indicated by the number 1 in Figure 12.1 and what is its functional significance


A) A band : length of myosin attached to an M line
B) H zone : area of myosin not overlapped by actin
C) Z line : anchors the thin filaments together
D) M line : where the tails of the myosin molecules are bound to one another
E) sarcomere : the functional unit of muscle contraction whose length is changed as a muscle shortens and lengthens

F) None of the above
G) All of the above

Correct Answer

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What area of a sarcomere shows up as light striations when viewed under a microscope?


A) Z line
B) A band
C) M line
D) H zone
E) I band

F) A) and E)
G) A) and B)

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What is the antagonistic muscle to the triceps?


A) brachialis
B) coracobrachialis
C) quadriceps
D) biceps
E) posterior deltoid

F) B) and C)
G) D) and E)

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The repeated, oscillating interaction between actin and myosin which results in the generation of force by a skeletal muscle cell is called what?


A) titin cycling
B) crossbridge cycling
C) the sliding -filament model
D) sarcomeric facilitation
E) Z line interaction

F) B) and E)
G) A) and E)

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Which muscle type contains actin and myosin?


A) smooth muscle only (single -unit or multi -unit)
B) skeletal and smooth muscle only
C) skeletal, smooth, and cardiac muscle
D) skeletal muscle only
E) smooth and cardiac muscle only

F) None of the above
G) A) and B)

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In order for crossbridge cycling to occur, the actin -myosin complex must be broken by which of the following?


A) conformational change that occurs as the myosin head changes from the high to low energy state
B) binding of tropomyosin to myosin
C) binding of ATP to myosin
D) binding of ATP to actin
E) binding of the troponin complex to actin

F) A) and C)
G) B) and E)

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Spontaneous depolarization of smooth muscle cells is mediated by pacemaker cells.

A) True
B) False

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The release of an inorganic phosphate from the myosin molecule directly results in which of the following?


A) breaking of the actin myosin complex
B) binding of actin to myosin
C) power stroke
D) cocking of the myosin head
E) development of rigor

F) A) and B)
G) D) and E)

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Contraction of motor units in a(n) _________manner allows a muscle to maintain a smooth level of force for a duration of time without fatiguing.


A) random
B) asynchronous
C) asymmetrical
D) symmetrical
E) synchronous

F) D) and E)
G) C) and D)

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Which of the following is NOT a property of glycolytic fibers as compared to oxidative fibers?


A) fewer capillaries
B) poor ability to produce ATP in the absence of oxygen
C) high capacity for lactic acid production
D) readily fatigable
E) absence of myoglobin

F) C) and D)
G) A) and E)

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Binding of ATP to myosin increases myosin's affinity for actin.

A) True
B) False

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Energy in the form of ATP is essential to the contractile process. Describe the cellular sources of energy for skeletal muscle fibers and how those energy sources play a role maintaining muscle activity at low -and high -intensities of activity.

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Energy in the form of ATP is required fo...

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What is the protein component of the thin filament that blocks the myosin -binding site on the actin monomer?


A) sarcoplasmic reticulum
B) tropomyosin
C) transverse tubule
D) troponin
E) actin

F) All of the above
G) C) and E)

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Which of the following is not part of the process whereby skeletal muscles relax?


A) The amount of calcium bound to troponin decreases.
B) A myosin -binding site on the actin molecule is blocked by tropomyosin.
C) The binding of calcium to a low -affinity site closes sarcoplasmic reticulum calcium channels.
D) Sarcolemmal calcium channels open to allow the efflux of calcium.
E) A calcium pump actively removes calcium.

F) B) and C)
G) A) and E)

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  -What is the structure indicated by the number 3 in Figure 12.1 and what is its functional significance? A)  A band : length of myosin attached to an M line B)  M line : where the tails of the myosin molecules are bound to one another C)  Z line : anchors the thin filaments together D)  sarcomere : the functional unit of muscle contraction whose length is changed as a muscle shortens and lengthens E)  H zone : area of myosin not overlapped by actin -What is the structure indicated by the number 3 in Figure 12.1 and what is its functional significance?


A) A band : length of myosin attached to an M line
B) M line : where the tails of the myosin molecules are bound to one another
C) Z line : anchors the thin filaments together
D) sarcomere : the functional unit of muscle contraction whose length is changed as a muscle shortens and lengthens
E) H zone : area of myosin not overlapped by actin

F) B) and E)
G) A) and B)

Correct Answer

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