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A patient's karyotype indicates a chromosome number of 45. This result is best explained by


A) nondisjunction in either the sperm cell or oocyte.
B) nondisjunction in both the sperm cell and oocyte.
C) fertilization of a single oocyte by two sperm cells.
D) a point mutation that caused one or more chromosomes to fuse.

E) A) and C)
F) A) and B)

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If the zygote splits into two separate cells, ________.


A) identical twins result
B) fraternal twins result
C) dizygotic twinning occurs
D) both cells die
E) paternal twins result

F) B) and C)
G) A) and D)

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Which structure(s) form(s) the roof of the mouth?


A) Mesonephros
B) Mandibular processes
C) Neural tube
D) Secondary palate
E) Somites

F) B) and C)
G) A) and C)

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The opening that connects the right and left atria in the fetal heart is the ________.


A) interatrial septum
B) septum primum
C) septum secundum
D) foramen ovale
E) foramen rotundum

F) A) and B)
G) A) and C)

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Alcohol ingestion by a pregnant woman can cause birth defects in her baby; in this respect, alcohol is a/an ________.


A) carcinogen
B) mutagen
C) teratogen
D) oncogene
E) haptogen

F) B) and E)
G) A) and D)

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An embryonic cell that contains the potential to give rise to any tissue type is called a/an ________ cell.


A) differentiated
B) multipotent
C) pluripotent
D) omnipotent
E) totipotent

F) D) and E)
G) B) and E)

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The embryonic heart


A) develops from two endothelial tubes that fuse together.
B) consists of four chambers.
C) has two atria but only one ventricle.
D) doesn't beat until just prior to birth.
E) has no passages connecting right side to left side.

F) B) and E)
G) All of the above

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Sally was a nice pink color when she was born. Her heart rate was high and her breathing was steady. However, she did not respond to plantar stimulation, though she did have some muscle movement. Her APGAR score would be ________.


A) 7
B) 6
C) 5
D) 4

E) None of the above
F) All of the above

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The placenta and membranes surrounding the embryo develop from the ________.


A) morula
B) blastocyst
C) trophoblast
D) inner cell mass
E) blastocele

F) C) and D)
G) B) and E)

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Developmental events are calculated from


A) ovulation.
B) conception.
C) the last menstrual period.
D) fourteen days after the last menstrual period.
E) fourteen days before the last menstrual period.

F) B) and D)
G) B) and C)

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Which germ layer is the thymus derived from?


A) Ectoderm
B) Mesoderm
C) Endoderm

D) B) and C)
E) All of the above

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Older people may require lower drug doses than younger people because ________.


A) their organs are more sensitive to drugs
B) they have lower rates of renal clearance
C) they do not absorb as much drug from the small intestine
D) there is less tissue mass to treat
E) a lifetime of mutations results in unpredictable drug reactions

F) A) and E)
G) C) and E)

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Which of the following statements concerning the embryonic cardiovascular system is true?


A) The heart develops from four endothelial tubes.
B) Blood vessels form from blood islands.
C) An opening in the interatrial septum is called the sinus venosus.
D) The bulbus cordis becomes the sinoatrial node (the adult pacemaker) .
E) There is an opening in the interventricular septum.

F) C) and D)
G) B) and C)

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Which of the following sequences is correct?


A) Mesonephros, pronephros, metanephros
B) Metanephros, pronephros, mesonephros
C) Pronephros, mesonephros, metanephros
D) Pronephros, metanephros, mesonephros
E) Mesonephros, metanephros, pronephros

F) C) and D)
G) B) and D)

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The onset of puberty is signaled by


A) a growth spurt.
B) emotional upheaval.
C) attainment of full adult stature.
D) the ability to obtain a drivers license.
E) a halt to growth.

F) A) and B)
G) D) and E)

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In some neonates, the foramen ovale does not close to form the fossa ovalis. This would be called a/an ________.


A) mutation
B) congenital disorder
C) teratogen
D) genetic anomaly

E) All of the above
F) A) and C)

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The allantois enlarges to form the ________.


A) kidney
B) gonads
C) ureter
D) urinary bladder
E) urethra

F) D) and E)
G) A) and E)

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Which of the following statements concerning musculoskeletal system development is true?


A) Skeletal muscles develop from crest cells.
B) Myoblasts produce somites.
C) The vertebral column develops from somite-derived mesoderm.
D) Enlargement of muscles after birth is due to an increase in the number of muscle fibers.
E) Ossification ends before birth.

F) A) and D)
G) B) and E)

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Type AB of the ABO blood group is an example of ________.


A) complete dominance
B) codominance
C) incomplete dominance
D) recessiveness
E) polymorphism

F) A) and D)
G) A) and B)

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Premature aging is called ________.


A) progeria
B) lactation
C) parturition
D) Alzheimer disease
E) dementia

F) None of the above
G) A) and C)

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