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If extracellular fluid osmolality is 385 mOsm/kg, the kidneys will increase reabsorption of ________.


A) urea
B) water
C) Na+
D) K+
E) Cl−

F) A) and D)
G) B) and E)

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In glomerulonephritis, the permeability of the filtration membrane increases, allowing proteins to cross the membrane. Which of the following would you expect to observe?


A) Increase in filtration volume
B) Anuria - no urine production
C) Necrosis of the renal corpuscle
D) Low protein levels in the filtrate
E) No change in the filtrate

F) All of the above
G) B) and C)

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Assuming all other values are normal, calculate the net filtration pressure in a patient with a drop in capsular hydrostatic pressure to 8 mmHg.


A) 10 mm Hg out
B) 20 mm Hg out
C) 30 mm Hg out
D) 40 mm Hg out
E) 50 mm Hg out

F) All of the above
G) A) and C)

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Intense sympathetic stimulation of the kidney


A) is necessary for normal kidney metabolism.
B) causes the release of epinephrine from the kidney.
C) decreases renal flow.
D) increases filtration rate.
E) does not alter filtration rate.

F) B) and D)
G) A) and E)

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Most water is reabsorbed from the filtrate in the ________.


A) proximal convoluted tubule
B) descending loop of Henle
C) ascending loop of Henle
D) distal convoluted tubule
E) collecting duct

F) None of the above
G) A) and B)

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In which of the following locations is filtrate osmolality highest?


A) End of proximal convoluted tubule
B) Tip of the loop of Henle
C) End of distal convoluted tubule
D) Beginning of distal convoluted tubule
E) Descending loop of Henle

F) A) and D)
G) B) and C)

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The kidneys are located behind the ________ membrane on the posterior side of the ________ wall.


A) peritoneal; abdominal
B) peritoneal; pelvic
C) renal; abdominal
D) renal; pelvic
E) pleural; pelvic

F) All of the above
G) D) and E)

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The kidney functions in


A) preventing blood loss.
B) white blood cell production.
C) synthesis of vitamin E.
D) excretion of metabolic wastes.
E) production of the hormone aldosterone.

F) C) and D)
G) A) and E)

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Urea is


A) secreted into the filtrate by cells of the distal convoluted tubule.
B) diffuse out of the collecting ducts into the interstitial fluid of the medulla and then diffuse into the descending loop of Henle.
C) completely reabsorbed by the nephron.
D) actively transported into the filtrate by cells of the collecting duct.
E) None of the choices are correct.

F) C) and E)
G) D) and E)

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Which of the following ions are cotransported across the wall of the proximal convoluted tubule, distal convoluted tubule, and the ascending limb of the loop of Henle?


A) sodium and bicarbonate
B) potassium and phosphate
C) sodium and chloride
D) bicarbonate and potassium
E) potassium and chloride

F) A) and B)
G) A) and C)

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Tubular secretion occurs in which of the following structures?


A) Glomerulus
B) Urethra
C) Renal pelvis
D) Distal convoluted tubule
E) Collecting duct

F) D) and E)
G) C) and E)

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What is the effect of intense sympathetic stimulation on the GFR?


A) GFR increases
B) GFR decreases
C) GFR is not affected
D) GFR increases, then decreases

E) A) and B)
F) All of the above

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Cortical tissue located between the pyramids is called the ________.


A) calyx tissue
B) renal papillae
C) renal columns
D) medullary rays
E) renal corpuscles

F) B) and D)
G) None of the above

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To calculate plasma clearance of any substance, it is necessary to know the


A) quantity of urine produced per minute.
B) concentration of the cleared substance in the urine.
C) concentration of the cleared substance in the blood.
D) All of the choices are correct.

E) A) and B)
F) All of the above

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Removal of the posterior pituitary will immediately cause


A) a decrease in urine volume.
B) an increase in urine volume.
C) no change in urine volume.

D) A) and B)
E) A) and C)

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Which of the following statements concerning the micturition reflex is false?


A) The micturition reflex is initiated by stretching the bladder wall.
B) Afferent signals are conducted to the sacral segments of the spinal cord by the pelvic nerves.
C) Efferent signals are sent to the bladder by sympathetic fibers in the pelvic nerve.
D) The micturition reflex usually produces a series of contractions of the urinary bladder.
E) The micturition reflex is modified by centers in the pons and cerebrum.

F) A) and D)
G) A) and E)

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When Na+ is actively transported from tubular cells to the interstitial fluid,


A) no energy is needed.
B) glucose and amino acids are countertransported at the same time.
C) Na+ concentration gradient is established between the tubule lumen and tubule cell.
D) water is countertransported by carrier molecules.
E) water is secreted.

F) A) and E)
G) None of the above

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Once inside the cells of the ascending limb, K+ and Cl− cross the basal membrane into the interstitial fluid by the process of ________.


A) facilitated diffusion
B) cotransport
C) counter transport
D) active transport
E) simple diffusion

F) A) and D)
G) D) and E)

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By the time filtrate reaches the tip of the loop of Henle, ________ of the filtrate volume has been reabsorbed.


A) 65%
B) 75%
C) 80%
D) 95%
E) 100%

F) A) and B)
G) C) and E)

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Arrange the following in the sequence in which filtrate moves through them. (1) Loop of Henle (2) Bowman capsule (3) Distal convoluted tubule (4) Proximal convoluted tubule


A) 1, 2, 3, 4
B) 4, 2, 1, 3
C) 2, 4, 3, 1
D) 2, 4, 1, 3
E) 3, 4, 1, 2

F) A) and D)
G) B) and E)

Correct Answer

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