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Tolerance is a state of ________.


A) hypersensitivity
B) transplant rejection
C) unresponsiveness to antigens
D) responding to self-antigens
E) non-recognition of antigens

F) A) and E)
G) A) and D)

Correct Answer

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Which of the following is a subpopulation of T cells?


A) Cytotoxic
B) Antigenic
C) Cytokinetic
D) Basophilic
E) Antitoxic

F) All of the above
G) None of the above

Correct Answer

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During the inflammatory response, ________.


A) vasoconstriction occurs
B) chemical mediators are released
C) vascular permeability is decreased
D) neutrophil production is depressed
E) blood flow is reduced

F) A) and D)
G) A) and C)

Correct Answer

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The secondary or memory response


A) occurs after the primary response has activated NK cells.
B) provides better protection than the primary response.
C) is less effective in antibody production.
D) produces different antibodies than those produced in the primary immune response.
E) does not protect the body after the first exposure.

F) B) and C)
G) A) and B)

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The type of cell responsible for the secondary response is a ________.


A) mast cell
B) macrophage
C) memory cell
D) red blood cell
E) monocyte

F) C) and E)
G) C) and D)

Correct Answer

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Which of the following is NOT an aging effect of the lymphatic system and immunity?


A) Fluid removal by the lymphatic capillaries is reduced.
B) Fewer antibodies are produced.
C) Onset of autoimmune diseases is unchanged.
D) T cell numbers remain constant, but they are less functional.

E) All of the above
F) C) and D)

Correct Answer

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In systemic inflammation, pyrogens ________.


A) decrease phagocytosis
B) decrease vasodilation
C) increase neutrophil production
D) stimulate fever production
E) are chemotactic factors

F) A) and B)
G) B) and E)

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A cell has engulfed a substance from the extracellular material and has migrated to a lymph node to interact with a helper T cell. Which of the following statements best describes this cell?


A) This is an antigen-presenting cell that interacts with the helper T cell through an MHC class II molecule.
B) This is an antigen-presenting cell that interacts with the helper T cell through an MHC class I molecule.
C) This is a cytotoxic T cell that interacts with the helper T cell through an MHC class II molecule.
D) This is a cytotoxic T cell that interacts with the helper T cell through an MHC class I molecule.

E) A) and C)
F) A) and B)

Correct Answer

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Match the term with the appropriate description. -Thymic corpuscles


A) Lipids that cause smooth muscle relaxation and vasodilation
B) Lymph nodules aggregated in the small intestinal wall
C) Rounded epithelial structures found in the medulla of thymus
D) Areas of a lymph node where lymphocytes divide
E) A chemical released from mast cells that causes vasodilation

F) B) and C)
G) A) and D)

Correct Answer

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Lymph is filtered by the ________.


A) tonsils
B) spleen
C) lymph nodes
D) thymus

E) None of the above
F) A) and C)

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Which of the following statements concerning immunity is correct?


A) Adaptive immunity responses to pathogens improves over time due to generation of memory, which includes an increase in the number of lymphocytes that respond faster than during the original infection.
B) Adaptive immunity demonstrates memory, meaning each lymphocyte responds to a particular pathogen, but responds similarly with each infection.
C) Adaptive immunity demonstrates specificity, which means that lymphocytes only destroy viruses and ignore all other types of pathogens.
D) All of the choices are correct.

E) A) and B)
F) C) and D)

Correct Answer

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Match the type of cell with its function. -Neutrophil


A) First cell to enter infected tissue
B) Will become macrophage in tissue
C) Lyses tumor and virus-infected cells
D) Cell that increases in number during a parasitic infection
E) Nonmotile cells in connective tissue that promote inflammation

F) B) and E)
G) A) and D)

Correct Answer

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The spleen


A) filters damaged red blood cells from the blood.
B) changes undifferentiated lymphocytes into competent lymphocytes.
C) is necessary for life. It can't be removed without causing death.
D) produces several different hormones with unknown function.
E) has additional digestive functions.

F) A) and C)
G) B) and E)

Correct Answer

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Match the appropriate characteristic with the type of immunity. -Mediated by T cells


A) Innate immunity
B) Antibody-mediated immunity
C) Cell-mediated immunity
D) Both antibody-mediated and cell-mediated immunity
E) Innate immunity, antibody-mediated immunity, and cell-mediated immunity

F) A) and E)
G) D) and E)

Correct Answer

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The immunoglobulin that is often the first antibody produced in response to an antigen is ________.


A) IgD
B) IgA
C) IgM
D) IgE
E) IgG

F) A) and B)
G) B) and D)

Correct Answer

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During a recent Ebola outbreak, clinicians attempted to collect "blood products" to help those infected with the virus fight the infection. Which of the following best relates this treatment to adaptive immunity?


A) The clinicians were hoping to use artificial passive immunity by introducing antibodies from those that survived the infection to individuals that were currently infected.
B) The clinicians were hoping to use artificial active immunity by introducing antigens from those that survived the infection to individuals that were currently infected.
C) The clinicians were hoping to use natural passive immunity by introducing antibodies from those that survived the infection to individuals that were currently infected.
D) The clinicians were hoping to use natural active immunity by introducing antibodies from those that survived the infection to individuals that were currently infected.

E) A) and B)
F) B) and D)

Correct Answer

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Match the term with the appropriate description. -Histamine


A) Lipids that cause smooth muscle relaxation and vasodilation
B) Lymph nodules aggregated in the small intestinal wall
C) Rounded epithelial structures found in the medulla of thymus
D) Areas of a lymph node where lymphocytes divide
E) A chemical released from mast cells that causes vasodilation

F) A) and B)
G) A) and C)

Correct Answer

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Match the appropriate characteristic with the type of immunity. -Antibodies produced


A) Innate immunity
B) Antibody-mediated immunity
C) Cell-mediated immunity
D) Both antibody-mediated and cell-mediated immunity
E) Innate immunity, antibody-mediated immunity, and cell-mediated immunity

F) B) and E)
G) A) and D)

Correct Answer

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Bean-shaped lymphatic organs found along lymphatic vessels are called ________.


A) lymph nodes
B) medullary cords
C) cisterna chyli
D) trabeculae
E) lymph nodules

F) All of the above
G) A) and E)

Correct Answer

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Interferon


A) directly attacks viruses.
B) protects cells that have been invaded by viruses.
C) increases vascular permeability.
D) is not produced by most cells.
E) is a protein that interferes with virus production and infection.

F) A) and D)
G) A) and E)

Correct Answer

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