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These collagen fibers help to connect ligaments and tendons to the periosteum of the bone.


A) Endosteal fibers
B) Sharpey fibers
C) Golgi fibers
D) Haversian fibers
E) Purkinje fibers

F) A) and E)
G) A) and B)

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Cartilage


A) is composed of osteons.
B) is surrounded by a membrane called the periosteum.
C) contains chondrocytes located in lacunae.
D) does not need nutrients and oxygen, so it has no blood vessels.
E) is well vascularized.

F) A) and E)
G) B) and E)

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How does the digestive system contribute to osteoporosis?


A) It is impacted by inadequate amounts of calcium and vitamin D in the diet.
B) Lack of exercise reduces muscle stress on bone.
C) Pain following injury helps prevent further injury.
D) Blood clotting starts repair process.
E) Calcitonin is used to treat osteoporosis.

F) C) and D)
G) B) and D)

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You would look for concentric lamellae


A) around the central canal of an osteon.
B) in between osteons.
C) on the outer surface of compact bone tissues.
D) as components of the cartilage.
E) in the bone marrow.

F) None of the above
G) All of the above

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The primary function of osteoblasts is to


A) prevent osteocytes from forming.
B) resorb bone along the epiphyseal plate.
C) inhibit the growth of bone.
D) stimulate bone growth.
E) lay down bone matrix.

F) A) and C)
G) A) and B)

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Osteogenesis imperfecta is


A) bone inflammation that often results from bacterial infection.
B) a disease in adults, especially women, characterized by a reduced amount of bone matrix.
C) a disease in adults characterized by softening of bones resulting from calcium depletion.
D) a disease in children characterized by soft, bowed, and swollen bones.
E) a group of genetic disorders producing very brittle bones that are easily fractured; this occurs because of insufficient collagen development.

F) B) and C)
G) C) and D)

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Which of the following is NOT a function of bone?


A) Support
B) Movement
C) Immunity
D) Calcium storage
E) Blood cell formation

F) A) and B)
G) A) and C)

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How does the urinary system contribute to osteoporosis?


A) Lack of exposure to sunlight increases vitamin D production at the kidneys and decreases calcium absorption.
B) Immune cells of the kidneys absorb excess calcium under the direction of PTH.
C) Excessive smoking lowers calcitriol levels, which decreases bone loss.
D) Calcium ions released from the bones are excreted as part of urine.
E) Decreased estrogen levels following menopause contribute to the disease.

F) B) and E)
G) A) and E)

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Which of the following is an example of how the endocrine system affects osteoporosis?


A) It is impacted by inadequate amounts of calcium and vitamin D in the diet.
B) Lack of exercise reduces muscle stress on bone.
C) Pain following injury helps prevent further injury.
D) Blood clotting starts repair process.
E) Calcitonin is used to treat osteoporosis.

F) C) and D)
G) A) and E)

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When a fracture begins to heal, one type of bone cell moves into the fracture site and tears down the damaged bone tissue. Which of the following does this?


A) Osteoclasts
B) Osteoblasts
C) Osteons
D) Matrix cells
E) Osteocytes

F) None of the above
G) C) and E)

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Which of the following occurs in the formation of mineralized bone matrix?


A) Hydrogen ions form an acid environment in bone matrix.
B) Osteoblasts form collagen and proteoglycans.
C) The protein components of bone matrix are digested.
D) Ca2+ is actively transported from bone matrix to the blood.
E) Blood calcium is elevated.

F) A) and B)
G) A) and C)

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A boy grew rapidly and reached a height of 6'2" by the time he was 13. He had normal body proportions and sexual development but had below normal mental cognition. Which of the following likely caused his condition?


A) An adrenal tumor that secretes androgens
B) Hypersecretion of testosterone
C) Elevated vitamin D synthesis
D) Hypersecretion of growth hormone
E) Hyposecretion of growth hormone

F) All of the above
G) A) and E)

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Which of the following statements regarding calcium homeostasis is true?


A) Parathyroid hormone inhibits osteoclast activity.
B) When blood calcium levels are too low, osteoclast activity increases.
C) Increased osteoblast activity increases blood calcium levels.
D) Parathyroid hormone increases calcium loss from the kidney.
E) Calcitonin elevates blood calcium levels.

F) All of the above
G) A) and D)

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The type of lamellae found in osteons (Haversian systems) is ________.


A) circumferential
B) concentric
C) interstitial
D) appositional
E) oppositional

F) A) and E)
G) A) and B)

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How does the muscular system contribute to osteoporosis?


A) It is impacted by inadequate amounts of calcium and vitamin D in the diet.
B) Lack of exercise reduces muscle stress on bone.
C) Pain following injury helps prevent further injury.
D) Blood clotting starts repair process.
E) Calcitonin is used to treat osteoporosis.

F) C) and E)
G) C) and D)

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The application of small electrical charges to broken bones are sometimes used to enhance healing.

A) True
B) False

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The sequence of events that produces growth at the epiphyseal plate is


A) hypertrophy, proliferation, calcification, ossification, and remodeling.
B) proliferation, hypertrophy, cell death, calcification, ossification, and remodeling.
C) hypertrophy, calcification, proliferation, cell death, ossification, and remodeling.
D) calcification, hypertrophy, proliferation, ossification, cell death, and remodeling.
E) proliferation, hypertrophy, calcification, cell death, ossification, and remodeling.

F) None of the above
G) B) and D)

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The longitudinal growth of long bones ceases when


A) chondroblasts take over mitosis of osteoblasts.
B) the epiphyseal plate is completely replaced with bone tissue.
C) the epiphysis becomes separated from the diaphysis.
D) the bone marrow forms.
E) the periosteum is completed.

F) D) and E)
G) B) and E)

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The collar that forms around the opposing ends of bone fragments is called a/an ________.


A) osteon
B) external callus
C) hematoma
D) epiphysis
E) internal callus

F) A) and B)
G) A) and C)

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Which type of bone cell gives rise to osteoblasts?


A) Osteochondral progenitor cell
B) Osteoblast
C) Osteocyte
D) Osteoclast

E) A) and B)
F) None of the above

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