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Helicobacter pylori causes ______.


A) gastritis
B) duodenal ulcers
C) stomach ulcers
D) increased risk for stomach cancer
E) All of the choices are correct.

F) D) and E)
G) B) and E)

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Which of the following statements is not true of enteroinvasive E. coli (EIEC) ?


A) High fever is present.
B) It invades the gut mucosa.
C) It makes no heat-labile or heat-stable exotoxins.
D) Blood and pus are found in the stool.
E) Prompt treatment with a broad-spectrum antibiotic is essential to recover from an infection.

F) C) and D)
G) None of the above

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Infection with which apicomplexan has been associated with fecal-contaminated drinking water?


A) Entamoeba histolytica
B) Ascaris lumbricoides
C) Cryptosporidium
D) Rotavirus

E) All of the above
F) None of the above

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The gastrointestinal tract has both a long tube that nutrients traverse from mouth to anus and accessory organs that aid in food digestion. From the following list of organs in the digestive system, identify the mismatch.


A) Appendix; accessory organ
B) Rectum; part of the digestive tube
C) Liver; part of the digestive tube
D) Salivary glands; accessory organ
E) Pharynx; part of the digestive tube

F) A) and B)
G) B) and D)

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It is now past the normal dinner time, but you do not even want to think about food. Only diarrhea, abdominal cramps, and vomiting are on your mind. This all started a few hours ago after having a ham sandwich for lunch purchased from a street vendor. With your microbiology knowledge, you surmise that it is a Staphylococcus aureus-related disorder. Why do you think this?


A) Staphylococcus aureus is the most common cause of gastrointestinal disease.
B) Ham is notorious for being contaminated with Staphylococcus aureus bacteria.
C) Only Staphylococcus aureus infection causes vomiting, along with cramps and diarrhea.
D) The toxin produced by Staphylococcus aureus was already in the ham, so the symptoms can occur quickly.

E) None of the above
F) B) and C)

Correct Answer

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The most immediate and important treatment needed to prevent death in cholera victims is ______.


A) broad-spectrum antimicrobials
B) water and electrolyte replacement
C) antitoxin
D) surgery

E) C) and D)
F) B) and C)

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Which of the following statements regarding shiga toxin-producing E. coli is correct?


A) It synthesizes shiga exotoxin from a bacteriophage.
B) It synthesizes shiga exotoxin from the E. coli chromosome.
C) It synthesizes shiga endotoxin from a bacteriophage.
D) It synthesizes shiga endotoxin from the E. coli chromosome.

E) A) and B)
F) A) and C)

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A current news story describes a cruise ship in the Caribbean with an outbreak of diarrheal illness, affecting hundreds of people. With all of those people in a small area, opening and closing doors, using handrails, etc, you are trying to ?gure out what infectious agent may be the cause. Your most likely guess is that the pathogen is ______.


A) hepatitis B
B) Clostridium di?cile
C) shiga-toxin-producing E. coli
D) norovirus
E) cholera

F) A) and D)
G) A) and C)

Correct Answer

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D

Escherichia coli infections _______.


A) are often transmitted by fecal contaminated water and food
B) include EIEC that destroys gut mucosa
C) involve enterotoxin in traveler's diarrhea
D) are self-limiting with the only treatment being rehydration
E) All of the choices are correct.

F) A) and E)
G) A) and D)

Correct Answer

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The transmission cycle of Fasciola hepatica differs from the cycles of Opisthorchis sinensis and Clonorchis sinensis in that _______.


A) freshwater snails release cercariae
B) helminth development occurs in the liver
C) encystment occurs on a freshwater plant
D) eggs are released from an infected human via the urine

E) B) and C)
F) A) and B)

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General symptoms of helminth infection includes all of the following except _______.


A) increased eosinophil count
B) eggs, larvae, or adult worms found in feces
C) increased sensitivity to helminth antigens
D) intense abdominal pain
E) vague nausea

F) A) and E)
G) A) and C)

Correct Answer

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Which of the following pathogens has an infectious dose so low that a single infectious particle (cell, cyst, endospore, virus) can cause disease?


A) Norovirus
B) Hepatitis A virus
C) Clostridium difficile
D) Shigella
E) Giardia

F) A) and B)
G) None of the above

Correct Answer

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Hepatitis B virus _______.


A) is principally transmitted by blood
B) transmission risks include shared needles, anal intercourse, and heterosexual intercourse
C) is transmitted to newborns from chronic carrier mothers
D) has many chronic carriers
E) All of the choices are correct.

F) None of the above
G) A) and D)

Correct Answer

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Which of the following statements regarding fecal transplant is correct?


A) Donors and recipients must be carefully matched to prevent an immune reaction in the recipient.
B) Fecal matter must be carefully disinfected and screened for viruses, cysts, and endospores before transfer to a recipient patient.
C) The goal is to completely eradicate Clostridium difficile from a patient's gut microbiota and replace it with a healthy community.
D) This treatment is designed to jump-start the intestinal microbiota after an infection with Clostridium difficile resuts in acute diarrhea.

E) A) and B)
F) All of the above

Correct Answer

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The fact that Salmonella has a high ID50 means that _______.


A) consuming just a few cells of Salmonella will not result in illness
B) it is more pathogenic than 50% of all gut microbes
C) the most stringent decontamination measures must be used in food preparation facilities
D) an antibiotic dose of 50 μg/ml can be expected to kill the organism

E) B) and C)
F) B) and D)

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A

Which of the following statements regarding tapeworms is incorrect?


A) Proglottids are reproductive segments.
B) The body is comprised of proglottids.
C) The scolex is the head.
D) They can produce a variety of toxins.
E) Cysticerci are young, infective larvae ingested in undercooked meat.

F) A) and C)
G) A) and B)

Correct Answer

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Which of the following statements regarding helminths causing intestinal distress plus migratory symptoms is incorrect?


A) Tissues along the migratory route of the helminth experience inflammation.
B) Praziquantel is the best treatment option for infection with these helminths.
C) All of these infections are associated with eosinophilia, which can be detected in a complete blood count.
D) Nearly all newborn puppies in the U.S. are infected with Toxocara species.

E) B) and D)
F) All of the above

Correct Answer

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B

Which of the following statements is not true regarding Clostridium difficile?


A) It produces "rice-water" stools.
B) Infection is precipitated by broad-spectrum antibiotic therapy.
C) It is also called pseudomembranous colitis.
D) It is part of the normal intestinal biota.
E) It is a gram-positive, endospore-forming rod.

F) B) and D)
G) All of the above

Correct Answer

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Which of the following antigen types found in gram-negative enterics is mismatched?


A) H antigen - flagellar
B) K antigen - capsule
C) O antigen - cell wall
D) All of the choices are correct matches.

E) All of the above
F) B) and D)

Correct Answer

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Outbreaks of which protozoan disease have been associated with fecal-contaminated imported raspberries, fresh greens, and drinking water?


A) Cyclosporiasis
B) Toxoplasmosis
C) Cryptosporidiosis
D) Trichinosis

E) C) and D)
F) A) and B)

Correct Answer

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