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Which of the following statements regarding Clostridium difficile infection is incorrect?


A) It is due to ingestion of contaminated, improperly stored, cooked meats and gravies.
B) It is a colitis that is a superinfection.
C) It is the major cause of diarrhea in hospitals.
D) It is associated with disruption of normal biota due to broad-spectrum antimicrobials.

E) C) and D)
F) A) and D)

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Which of the following groups of microorganisms is not found among the normal gut microbiota?


A) Firmicutes (Streptococcus, Staphylococcus, Clostridium, Bacillus)
B) Protozoa (Entamoeba, Trichomonas)
C) Spirilla (Leptospira, Borrelia)
D) Fungi (Candida)
E) Enterics (Escherichia, Enterobacter)

F) C) and D)
G) A) and D)

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Vibrio cholerae can be readily isolated and identified in the laboratory from stool samples by _______.


A) its ability to grow at high temperature and produce zones of clearing on blood agar
B) its robust chemotactic response to the presence of chitin
C) growth on selective media followed by PCR of its 16S rRNA gene
D) dark-field microscopy looking for motility

E) B) and D)
F) None of the above

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The primary viral cause of chronic diarrhea globally is ______.


A) rotavirus
B) Cryptosporidium
C) adenovirus
D) norovirus
E) arbovirus

F) C) and D)
G) A) and C)

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The causative organism for mumps is ______.


A) Corynebacterium diphtheriae
B) Morbillivirus
C) Vibrio cholerae
D) Paramyxovirus
E) Streptococcus pyogenes

F) All of the above
G) A) and B)

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Which of the following is not true of schistosomiasis?


A) Larvae called cercariae can penetrate intact skin through hair follicles.
B) Freshwater snails are the intermediate host.
C) Schistosomiasis is caused by blood ?ukes.
D) Schistosomiasis covers its outer surface with blood proteins to escape detection by the immune system.
E) Schisotosomiasis cases are beginning to appear in the southern U.S., as climate change brings warming waters to the region.

F) A) and E)
G) None of the above

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Enteropathogenic E. coli (EPEC) causes gut effacement with shiga toxin.

A) True
B) False

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Both Taenia and Trichinella can be found as cysts embedded in pork muscle. Which of the following statements about these organisms is incorrect?


A) Both helminths can exit the digestive system and migrate to other tissues.
B) Both organisms release eggs in the feces to propagate the helminth.
C) For both organisms, cyst envelopes are digested in the stomach, releasing the larvae to the intestine.
D) Only Taenia can be transmitted from one human to another.

E) A) and D)
F) A) and C)

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The most dangerous outcome of a Taenia solium infection occurs when humans ingest tapeworm eggs rather than cysticerci. This type of transmission occurs by _______.


A) consuming plants that haven't been thoroughly washed of soil
B) drinking water contaminated with feces from infected animals
C) consuming undercooked pork with encysted Taenia
D) consuming "chitlins," pig intestines from an infected animal

E) A) and D)
F) A) and C)

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Carriers of Hepatitis B virus are not common.

A) True
B) False

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Which of the following statements regarding Campylobacter infection is incorrect?


A) Campylobacter burrows into the mucosa of the ileum and multiplies.
B) It can cause acute temporary paralysis.
C) It can lead to Guillain-Barre syndrome.
D) It can last over 2 weeks.
E) It is caused by a shiga toxin.

F) A) and B)
G) A) and C)

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A metagenomic study from a never-before-seen type of gingival infection indicates the presence of large numbers of archaea. Which of the following would be a good practice to isolate this organism?


A) Adjust the pH of the medium to below 5.
B) Incubate the isolation medium at about 90°C.
C) Incubate the isolation medium adjacent to a bright full-spectrum light.
D) Use an anaerobic medium and incubate in a sealed container.

E) C) and D)
F) None of the above

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Shiga toxin-producing E. coli characteristics include all of the following except that it _______.


A) causes a bloody diarrhea
B) only causes occupational illness in people who work with animals
C) is transmitted by ingestion of contaminated, undercooked food, especially hamburger
D) in some cases, leads to the development of hemolytic uremic syndrome (HUS) with possible kidney failure
E) has a reservoir inside of cattle intestines

F) D) and E)
G) A) and C)

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Enterotoxin production is a characteristic of ______.


A) Clostridium botulinum
B) Clostridium perfringens
C) Clostridium tetani
D) Clostridium difficile

E) C) and D)
F) None of the above

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The most definitive test to diagnose a helminth infection is _______.


A) an ova and parasite smear for microscopy
B) a serological test for the presence of anti-helminthic antibodies
C) a blood cell count to look for elevated levels of eosinophils
D) a good medical history of the patient, including recent foreign travel

E) B) and C)
F) A) and C)

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Pathogenicity islands are _______.


A) enzymes like proteases and hemolysins that promote pathogenesis
B) closely related groups of pathogenic enteric organisms
C) a lymphoid tissue present in the small intestine
D) gene clusters that confer the ability to become pathogenic

E) A) and B)
F) All of the above

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Which of the following statements comparing Enterobius vermicularis and Diphyllobothrium latum is incorrect?


A) Symptoms of both infections are mild.
B) E. vermicularis is best treated with mebendazole, whereas D. latum is susceptible to praziquantel.
C) D. latum has fish as an intermediate host, whereas E. vermicularis has no intermediate host.
D) Both helminths affect primarily children.

E) B) and C)
F) A) and D)

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"Rice-water stools" are associated with disease caused by which organism?


A) Campylobacter jejuni
B) Vibrio parahaemolyticus
C) Vibrio cholerae
D) Helicobacter pylori
E) Vibrio vulnificus

F) B) and E)
G) A) and E)

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In the absence of dietary carbohydrates, bacteria do not cause tooth decay.

A) True
B) False

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The best treatment for acute diarrhea is oral replacement of electrolytes and water.

A) True
B) False

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