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Which of the following is not part of the lower respiratory system?


A) Alveoli
B) Bronchi
C) Bronchioles
D) Trachea
E) Sinuses

F) A) and C)
G) D) and E)

Correct Answer

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The major virulence factor of Corynebacterium diphtheriae that causes serious systemic effects is its ______.


A) capsule
B) metachromatic granules
C) exotoxin
D) endospores
E) endotoxin

F) B) and D)
G) A) and E)

Correct Answer

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The most common mode of transmission for sinusitis is _______.


A) exotoxin
B) direct contact
C) indirect contact
D) endogenous infection
E) droplet contact

F) A) and C)
G) A) and B)

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Rheumatic fever is caused by a/an ______ infection.


A) primary streptococcal
B) primary viral
C) opportunistic streptococcal
D) endogenous

E) B) and C)
F) C) and D)

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Respiratory syncytial virus _______.


A) causes serious disease in infants 6 months old or younger
B) uses the nasopharynx as its main replication site
C) can be treated with the antiviral aerosol ribavirin
D) has symptoms of dyspnea and rales
E) All of the choices are correct.

F) A) and C)
G) D) and E)

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Legionellosis is a zoonosis.

A) True
B) False

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The bright red rash and fever of scarlet fever is due to _______.


A) enterotoxins
B) hemolysins
C) toxic shock syndrome toxin
D) exfoliative toxin
E) erythrogenic toxin

F) A) and C)
G) A) and E)

Correct Answer

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Annual influenza vaccinations are important for all individuals because _______.


A) the virus is stable so once the vaccine is administered, protection from antibodies is lifelong
B) the vaccine prevents secondary infections in individuals with influenza
C) the oral-fecal transmission route makes it easy to pass to others
D) the highly contagious nature of the virus means that transmission from a robust individual to those with a weaker immune system, such as the young or the elderly, is facilitated in

E) A) and B)
F) A) and C)

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The highest incidence of histoplasmosis in the United States occurs in the ______.


A) southeast
B) southwest
C) east and Midwest
D) northeast
E) Rocky Mountains

F) B) and D)
G) B) and C)

Correct Answer

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Your patient has pneumonia. Since there are so many microorganisms causing pneumonia, what might be the best test to do first for identification of the agent?


A) An antibody test
B) A culture from a lung aspirate
C) A skin test
D) A Gram stain of a saliva specimen

E) A) and C)
F) B) and C)

Correct Answer

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Respiratory syncytial virus is a major cause of global respiratory infection outbreaks in infants 6 months of age or younger.

A) True
B) False

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An induration of less than 5mm in the Mantoux test is negative for TB.

A) True
B) False

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The difference between CAP and HCAP is that _______.


A) CAP symptoms include nausea and vomiting whereas HCAP involves the upper respiratory tract only
B) CAP may be caused by a variety of pathogens including Streptococcus pneumoniae, as well as viruses and mycoplasmas, whereas HCAP is predominantly caused by methicillin-
Resistant Staphylococcus aureus
C) CAP has a higher mortality rate that HCAP because the causative organisms are more pathogenic
D) CAP is caused by gram-positive bacteria whereas HCAP is caused by gram-negative bacteria

E) None of the above
F) B) and C)

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Which opportunist is the most frequent cause of life-threatening pneumonia in AIDS patients?


A) Cryptococcus neoformans
B) Candida albicans
C) Malassezia furfur
D) Pneumocystis (carinii) jiroveci

E) A) and D)
F) B) and C)

Correct Answer

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What is the function of normal biota of the respiratory tract?


A) Competes with pathogens for resources and space
B) Microbial antagonism
C) Provides antibodies
D) Both competes with pathogens for resources and space / microbial antagonism are correct.

E) B) and C)
F) C) and D)

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Which of the following causes a noncommunicable pulmonary infection that resembles tuberculosis?


A) Mycobacterium avium complex (MAC)
B) Mycobacterium kansasii
C) Mycobacterium scrofulaceum
D) Mycobacterium fortuitum complex
E) Mycobacterium marinum

F) A) and D)
G) B) and C)

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When the centers of tubercles break down into _____ lesions, they gradually heal by calci?cation that replaces normal lung tissue.


A) primary
B) secondary
C) necrotic caseous
D) granuloma
E) tertiary

F) A) and E)
G) B) and C)

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Your dog has ?u caused by an H?N8 strain. Assume that you breathe in this strain, after you have already come in contact with an H1N1 strain. Both viruses go into the cells of your upper respiratory tract. During the viral replication cycle inside of your epithelial cells, genetic information for hemagglutinin antigen and for neuraminidase antigen are recombined. Your cells end up producing a new variant---H?N1. Predict what might happen as a result of this set of events.


A) Only people who have never had ?u before will get sick from the new H?N1 variant.
B) This is not a problem because the human immune system can respond quickly to any new antigens never seen before.
C) This novel virus will spread through the human population without much resistance.
D) Since this new virus has antigens from a dog strain, the new strain will not be able to infect human cells.

E) None of the above
F) B) and C)

Correct Answer

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The high mortality rate for patients with MDR-TB and XDR-TB is due in part because of the severe side effects from the daily multidrug regimen and the stimulation of a strong cell-mediated immune response.

A) True
B) False

Correct Answer

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Secondary bacterial infections may occur with the common cold.

A) True
B) False

Correct Answer

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