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The presence of Neisseria in a sample of cerebrospinal fluid indicates that _______.


A) the patient has an infection with Neisseria
B) the patient has previously had an infection with Neisseria
C) there is a deficiency in the patient's blood-brain barrier
D) the patient is healthy; Neisseria is part of the normal biota

E) None of the above
F) B) and D)

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Tetanus differs from botulism in that _______.


A) tetanus results in flaccid paralysis, while botulism paralysis is rigid
B) tetanus results from an exotoxin, botulism from an endotoxin
C) there is a vaccine for botulism but not for tetanus
D) muscles cannot relax in tetanus, while muscles cannot contract in botulism
E) All of the choices are correct.

F) A) and E)
G) A) and C)

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Pneumovax is a vaccine for prevention of disease caused by strains of Neisseria meningitidis.

A) True
B) False

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Each of the following statements is true for Toxoplasma gondii except that _______.


A) infection often fatal for AIDS patients
B) it can cause stillbirth
C) it has a narrow host range
D) it is a flagellated parasite

E) A) and B)
F) A) and C)

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Cultivation of Coccidioides species to confirm a diagnosis of Valley Fever is accomplished by plating the samples on ______ agar.


A) chocolate
B) blood
C) Sabourad's
D) birdseed

E) None of the above
F) A) and D)

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The food-borne disease that involves neurotoxin is ______.


A) botulism
B) Bacillus cereus intoxication
C) gastrointestinal anthrax
D) Clostridium perfringens gastroenteritis

E) A) and B)
F) All of the above

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Prions can be transmitted by all of the following except _______.


A) ingesting brain material
B) ingesting meat from infected animals
C) surgical instruments
D) cornea transplants
E) All of the choices have been documented as methods of prion transmission.

F) B) and C)
G) A) and C)

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The organism found in contaminated powdered infant formula that can cause meningitis is ______.


A) Escherichia coli O157:H7
B) Cronobacter sakazakii
C) Cryptococcus neoformans
D) Escherichia coli K1
E) Streptococcus agalactiae

F) A) and B)
G) B) and E)

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Production of a neurotoxin that prevents acetylcholine release from motor neurons at neuromuscular junctions is a characteristic of ______.


A) Clostridium tetani
B) Clostridium perfringens
C) Clostridium botulinum
D) Clostridium difficile

E) A) and B)
F) A) and C)

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Both Streptococcus pneumoniae and Cryptococcus neoformans are causes of meningitis, and both are diagnosed by microscopic observation. How are they distinguished in the microscope?


A) Cryptococcus is a fungus whereas Streptococcus is a bacterium; cells will be dramatically different in complexity and size.
B) These organisms have different cellular arrangements; Streptococcus form chains, whereas Cryptococcus forms irregular clusters of cells.
C) Because Cryptococcus is a fungus, it will not react in the Gram stain, and the cells will always remain colorless.
D) Streptococcus has a prominent capsule that can be observed by negative staining of the sample.

E) A) and B)
F) A) and C)

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In paralytic polio, which structures are damaged?


A) Sensory nerves
B) Brain stem
C) Anterior horn cells
D) Diaphragm
E) Peripheral nerves

F) All of the above
G) A) and D)

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Some cases of CJD may be caused by a mutation of the PrP gene.

A) True
B) False

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Which of the following pertains to both tetanus and foodborne botulism?


A) They are caused by enterotoxins of the pathogen.
B) Nausea and diarrhea are symptoms.
C) An exotoxin blocks acetylcholine release.
D) They occur when endospore-contaminated soil enters deep wounds.
E) Treatment involves antitoxin therapy.

F) A) and D)
G) All of the above

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In both botulism and tetanus, respiratory muscles cannot facilitate breathing and, if untreated, respiratory collapse leads to death.

A) True
B) False

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Which of the following does not apply to Neisseria meningitidis?


A) It can be easily transmitted in day care facilities, dorms, and military barracks.
B) It is a common cause of bacterial pneumonia.
C) It causes a serious meningitis.
D) Its reservoir is the nasopharynx of human carriers.
E) Its virulence factors include a capsule, pili, endotoxin, and IgA protease.

F) B) and E)
G) A) and B)

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The preferred preventative measure for polio in the United States is the _______.


A) inactive vaccine developed by Jonas Salk
B) oral, active vaccine developed by Jonas Salk
C) inactive vaccine developed by Albert Sabin
D) oral, active vaccine developed by Albert Sabin
E) No preventative measures are used because polio has been eradicated in the United States.

F) All of the above
G) A) and B)

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Arthrospores of Coccidioides immitis develop into ______ that will release endospores into the lungs.


A) capsules
B) hyphae
C) buds
D) capsids
E) spherules

F) A) and B)
G) B) and D)

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Patients with Creutzfeldt-Jacob disease live ______ post diagnosis.


A) less than 1 year
B) 1 to 5 years
C) 5 to 10 years
D) 10 to 20 years
E) greater than 25 years

F) C) and E)
G) A) and B)

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What is the likelihood that a patient infected by West Nile virus will develop West Nile encephalitis?


A) Less than 1%
B) Between 1% and 10%
C) Between 10% and 15%
D) Greater than 20%
E) Greater than 50%

F) All of the above
G) A) and D)

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A group is planning a cross-country hike on the Paci?c Crest Trail, from the Mexican border, through California, Oregon, and Washington, to the Canadian border. Which of the following should not be a concern for the group while on this trip?


A) Rabies
B) Valley Fever
C) Powassan Virus
D) West Nile Encephalitis

E) A) and C)
F) None of the above

Correct Answer

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