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The allergen in poison ivy plants is an oil called urushiol.

A) True
B) False

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Which of the following is not a possible outcome of a type I hypersensitivity reaction?


A) Sneezing
B) Rhinitis
C) Rashes
D) Contact dermatitis
E) Diarrhea

F) B) and E)
G) C) and E)

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In multiple sclerosis, autoantibodies attack _______.


A) acetylcholine receptors on smooth muscle
B) myelin sheath cells of the nervous system
C) sodium pump proteins in the cell membrane
D) acetylcholine receptors on skeletal muscle
E) cells in thyroid follicles

F) A) and D)
G) A) and E)

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In the theory for allergic desensitization, which immunoglobulin blocks the allergen from binding with IgE?


A) IgD
B) IgA
C) IgE
D) IgG
E) IgM

F) A) and D)
G) A) and C)

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Many men make antibodies to sperm, resulting in destruction of sperm to the point of sterility. What would be the likely origin of this autoimmune disease?


A) Since sperm are not made until after puberty, the immune system cannot scan the antigens on the sperm for immune tolerance. After sperm are made and the immune system sees them, they are recognized as foreign.
B) T helper cells erroneously identify sperm cells as foreign invaders, triggering the T cytotoxic cells to start killing sperm.
C) These antibodies are produced as a result of mutations in T lymphocytes, causing them to make large amounts of antibody.
D) Antigens on sperm cells are similar to antigens on a variety of bacteria like Streptococcus. After a strep throat caused by Streptococcus, the immune system produces antibodies to

E) All of the above
F) C) and D)

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Which type/s of hypersensitivities is IgG is involved with?


A) Anaphylaxis
B) Antibody-mediated
C) Immune complex-mediated
D) Both anaphylaxis and antibody-mediated
E) Both antibody-mediated and immune complex-mediated

F) A) and D)
G) D) and E)

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Systemic anaphylaxis can quickly result in airway blockage, shock, and death.

A) True
B) False

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Tissue transplanted from one body site on a patient to a different body site on that patient is called a/an ______.


A) isograft
B) allograft
C) autograft
D) hypograft
E) xenograft

F) B) and C)
G) C) and D)

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A person with O type blood _______.


A) lacks all of the alleles for ABO blood type
B) could not have the Rh factor
C) lacks A and B antigens
D) is called a universal recipient

E) B) and D)
F) C) and D)

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A seasonal reaction to inhaled allergens is ______.


A) asthma
B) anaphylaxis
C) atopic dermatitis
D) eczema
E) allergic rhinitis

F) B) and E)
G) None of the above

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The serum of a person with blood type A and Rh- will have the ability to make which of the following antibodies?


A) Anti-B and anti-Rh
B) Anti-A and anti-Rh
C) Anti-B
D) Anti-A
E) Anti-A, anti-B, and anti-Rh

F) B) and E)
G) None of the above

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Autoimmunity is typically due to _______.


A) autoantibodies and T cells
B) a deficiency in T-cell development
C) a transfusion reaction
D) IgE and mast cells
E) graft rejection

F) A) and D)
G) B) and E)

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Serum sickness and the Arthus reaction are both type III hypersensitivities, but they differ in that _______.


A) serum sickness is vomiting and diarrhea in response to animal serum, whereas the Arthus reaction causes arthritis
B) serum sickness is an infection in the blood serum, whereas the Arthus reaction is a swelling in the joints
C) serum sickness is a localized reaction to an injected therapy, whereas the Arthus reaction is systemic
D) serum sickness is a systemic reaction to an injected therapy, whereas the Arthus reaction remains localized to the injection site

E) A) and B)
F) A) and C)

Correct Answer

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Allergies run in families because _______.


A) immunoglobulins pass through breast milk
B) the variable region of antibodies is genetically determined
C) immunoglobulins pass from mother to fetus
D) the relative production of IgE is inherited

E) All of the above
F) A) and D)

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A systemic, sometimes fatal, reaction with airway obstruction and circulatory collapse is _______.


A) delayed
B) T-cell-mediated
C) antibody-mediated
D) systemic anaphylaxis
E) atopic

F) B) and E)
G) A) and E)

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A person who produces anti-A and anti-B serum antibodies will have blood type _______.


A) A
B) O
C) Rh
D) B
E) AB

F) B) and C)
G) B) and D)

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DiGeorge syndrome is the result of _______.


A) delayed hypersensitivity
B) congenital absence or immaturity of the thymus gland
C) failure of B-cell development and maturity
D) autoantibodies
E) a genetic defect in the development of both T cells and B cells

F) B) and C)
G) B) and D)

Correct Answer

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Large quantities of antibodies that react to the second entry of antigen and lead to formation of antigen-antibody complexes occurs in _______.


A) delayed hypersensitivity
B) anaphylaxis
C) hemolytic disease of the newborn
D) serum sickness

E) A) and B)
F) A) and C)

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A person who is Rh- will have anti-Rh antibodies in his/her serum from early infancy.

A) True
B) False

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All of the following are associated with IgE and mast-cell-mediated allergy except ______.


A) drug allergies
B) eczema
C) anaphylaxis
D) allergic asthma
E) systemic lupus erythematosus

F) B) and E)
G) A) and D)

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