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The immunoglobulin class that has an Fc region that binds to receptors on basophils and mast cells is ______.


A) IgG
B) IgM
C) IgA
D) IgD
E) IgE

F) D) and E)
G) A) and E)

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Superantigens are _______.


A) body tissues that the immune system mistakes as foreign
B) cell markers found in some member of a species but not in other members
C) bacterial toxins that activate T cells at a 100 times greater rate than other antigens
D) antigens that evoke allergic reactions

E) A) and B)
F) None of the above

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An example of artificial passive immunity would be _______.


A) chickenpox infection, followed by lifelong immunity
B) chickenpox vaccine triggering extended immunity to chickenpox
C) giving a person immune serum globulins to chickenpox virus after exposure to the disease
D) a fetus acquiring maternal IgG to the chickenpox virus across the placenta

E) C) and D)
F) A) and D)

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An example of natural passive immunity would be _______.


A) a fetus acquiring maternal IgG to the chickenpox virus across the placenta
B) giving a person immune serum globulins to chickenpox virus after exposure to the disease
C) chickenpox vaccine triggering extended immunity to chickenpox
D) chickenpox infection, followed by lifelong immunity

E) A) and B)
F) A) and C)

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Lymphocytes _______.


A) possess MHC antigens for recognizing self
B) have membrane receptors that recognize foreign antigens
C) gain tolerance to self by destruction of lymphocytes that could react against self
D) develop into clones of B and T cells with extreme variations of specificity
E) All of these choices are correct.

F) A) and B)
G) B) and C)

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Gamma globulin can be given as immunotherapy to confer artificial passive immunity.

A) True
B) False

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Killed or inactivated vaccines are prepared by _______.


A) passage of the pathogen through unnatural hosts or tissue culture
B) removal of virulence genes from the microbe
C) treatment with formalin, heat, or radiation
D) long-term subculturing of the microbe

E) A) and B)
F) B) and C)

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The immunoglobulin class that is the only one capable of crossing the placenta is ______.


A) IgE
B) IgG
C) IgM
D) IgD
E) IgA

F) A) and E)
G) B) and C)

Correct Answer

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What type of cells secrete antibodies?


A) Plasma cells
B) Antigen-presenting cells
C) Helper T cells
D) Memory B cells
E) Cytotoxic T cells

F) All of the above
G) A) and C)

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One plasma cell will secrete antibodies of various classes, but the antibodies will all have the same speci?city.

A) True
B) False

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Which of the following is not a target for TC cells?


A) Pig transplanted heart
B) Bacteria
C) Cancer cells
D) Human transplanted liver
E) Virus-infected cells

F) C) and D)
G) None of the above

Correct Answer

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Acquired specific immunity involves the response of _______.


A) skin barriers
B) B and T lymphocytes
C) lysozyme
D) interferon
E) mucus membranes

F) C) and E)
G) A) and B)

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Helper T cells _______.


A) secrete antibodies
B) suppress immune reactions
C) function in allergic reactions
D) directly destroy target cells
E) activate B cells and other T cells

F) A) and C)
G) C) and D)

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B and T lymphocytes are specific; they have only a single type of cell marker on their surface.

A) True
B) False

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Acellular vaccines and subunit vaccines _______.


A) contain modified bacterial exotoxin molecules
B) contain select antigenic components of a pathogen rather than whole cells or viruses
C) utilize DNA strands that will produce the antigen
D) confer passive immunity
E) are always genetically engineered

F) A) and D)
G) A) and C)

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The immunoglobulin/s found on the surface of B cells is/are _______.


A) IgM only
B) IgG only
C) IgD only
D) IgM and IgD
E) IgD and IgE

F) D) and E)
G) A) and D)

Correct Answer

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Which of the following is a special binding substance that enhances immunogenicity and prolongs antigen retention at the injection site?


A) Adjuvant
B) Gamma globulin
C) Booster
D) "Trojan horse" recombinant vaccine
E) Antibodies to toxin

F) B) and D)
G) B) and C)

Correct Answer

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T cell response to T-dependent antigens requires _______.


A) typically a protein antigen
B) binding of the T cell to a class II MHC receptor on a macrophage
C) binding of the T cell to a site on the antigen
D) interleukin-1 activating the T helper cell
E) All of these choices are correct.

F) A) and D)
G) All of the above

Correct Answer

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Which is incorrect about the Fc region of an immunoglobulin?


A) It is called the crystallizable fragment.
B) It contains an effector molecule that can fix complement.
C) It forms the antigen binding sites.
D) It contains an effector molecule that can bind to cells such as macrophages and mast cells.
E) It determines the class to which the immunoglobulin belongs.

F) B) and E)
G) B) and C)

Correct Answer

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Cytotoxic T cells _______.


A) secrete interleukin-2 to stimulate B and T cells
B) are activated by free, soluble antigens
C) lack specificity for antigen
D) secrete granzymes and perforins that damage target cells

E) A) and B)
F) None of the above

Correct Answer

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