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The subjective evidence of disease sensed by the patient is termed a/an ______.


A) syndrome
B) symptom
C) sign
D) pathology
E) inflammation

F) None of the above
G) A) and E)

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The term infection refers to _______.


A) microorganisms colonizing the body
B) contact with microorganisms
C) contact with pathogens
D) pathogens penetrating host defenses

E) B) and C)
F) A) and B)

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The stage of an infectious disease when specific signs and symptoms are seen and the pathogen is at peak activity is the ______.


A) prodromal stage
B) convalescent stage
C) incubation period
D) period of invasion

E) B) and C)
F) B) and D)

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Septicemia means that a pathogen is present and multiplying in the blood.

A) True
B) False

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Which of the following is the endotoxin?


A) Hemolysin
B) Hyaluronidase
C) Streptokinase
D) Collagenase
E) Lipopolysaccharide

F) A) and B)
G) None of the above

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Your patient has a rash, a fever, and a very high white blood cell count. Blood specimens are taken, put into culture bottles, and sent down to the microbiology lab for incubation and analysis. Select the statement that best re?ects why microbial analysis of blood is an important step in patient diagnosis.


A) Microbial growth in blood samples may indicate sepsis.
B) A few bacterial cells in a blood sample are no big deal and should be ignored.
C) Blood specimens are often obtained through poor aseptic technique by the healthcare worker: this is documentation of their failure to employ proper universal precautions.
D) A lack of microbes in the blood means that the patient's health is critical.

E) B) and C)
F) A) and D)

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Treponema pallidum is the bacterium that causes syphilis. The gram-negative spirochete has never been cultured on bacteriological media. Select the statement that most accurately describes this disease-causing microbe.


A) There is no way to perform an epidemiological study on this disease.
B) Koch's postulates cannot be ful?lled for this disease.
C) Because the bacterium cannot be grown, there is no way to characterize the organism as to staining features, biochemical test reactions, molecular testing, etc.
D) There is no satisfactory way to identify the disease without being able to grow it.

E) B) and C)
F) All of the above

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The number of new cases of a disease in a population over a specific period of time compared with the healthy population is the ______.


A) mortality rate
B) morbidity rate
C) incidence rate
D) prevalence rate
E) epidemic rate

F) A) and B)
G) A) and C)

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Which genus is resident biota of the mouth, large intestine, and within the vagina from puberty to menopause?


A) Lactobacillus
B) Treponema
C) Haemophilus
D) Escherichia
E) Clostridium

F) C) and D)
G) A) and B)

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The term _______ refers to the presence of small numbers of bacteria in the blood.


A) bacteremia
B) septicemia
C) viremia
D) toxemia

E) C) and D)
F) All of the above

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John Snow famously traced a London outbreak of cholera to a pump on Broad Street. This cholera outbreak was an example of a _________ epidemic.


A) point-source
B) propagated
C) common-source

D) All of the above
E) None of the above

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The difference between the terms pathogenicity and virulence is that _______.


A) pathogenic organisms cause disease, virulent organisms do not
B) virulent organisms cause disease, pathogens do not
C) pathogens cause disease and their virulence describes the degree of pathogenicity
D) virulent organisms cause disease and their pathogenicity describes the degree of disease manifestations

E) B) and C)
F) A) and C)

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Since the 1970s, approximately 40 new infectious disease agents have been discovered, including SARS, chikungunya and Zika. The ability of these agents to spread rapidly and cause global concern is due to all of the following except _______.


A) individuals are traveling more frequently and farther distances than in the previous half- century
B) communities are becoming more sparsely populated
C) communities are spreading into rural areas/wildlife habitats
D) communities are becoming more densely populated

E) B) and C)
F) C) and D)

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Exotoxins ______.


A) are secreted by pathogenic organisms
B) are bound to the membrane of pathogenic organisms
C) are bound to the cell wall of pathogenic organisms
D) cause more damage than endotoxins
E) are host speci?c

F) B) and E)
G) A) and D)

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All communicable diseases ______.


A) are contagious
B) only occur in animals
C) are caused by microorganisms or their products
D) are caused by vectors
E) involve viruses as the pathogen

F) A) and D)
G) C) and D)

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The su?x -emia means ______.


A) blood
B) a disease or morbid process
C) an in?ammation
D) tumor
E) pertaining to

F) A) and B)
G) A) and E)

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