Question 1

Which of the following is incorrect about prophages?

Accepted Answer

A)   Present when the virus is in lysogeny
B)   Formed when viral DNA enters the bacterial chromosome
C)   Replicated with host DNA and passed on to progeny
D)   Cause lysis of host cells
E)   Occur when temperate phages enter host cellsF) A) and E)
G) A) and C)

Question 2

Tami?u is a common medication given for in?uenza treatment. It works by protecting and blocking sialic acid molecules on the surfaces of host cells and in?uenza virus envelopes as they leave the cell. Which statement re?ects the mechanism of Tami?u's action?

Accepted Answer

A)   Tami?u blocks protein synthesis of the viral genome.
B)   Tami?u interferes with the replication of +ssRNA from the -ssRNA genome of the ?u virus.
C)   Tami?u interferes with the release of the budding viruses from the infected host cells.
D)   Tami?u interferes with the metabolic properties of the virus.E) A) and B)
F) A) and C)

Question 3

A/an _______ is the protein shell around the nucleic acid core of a virus.

Accepted Answer

A)   capsomere
B)   capsid
C)   spike
D)   envelope
E)   monolayerF) None of the above
G) B) and D)

Question 4

Viruses are used to produce vaccines for prevention of certain viral infections.

Accepted Answer

A) True 
 B)False

Question 5

Persistent viruses that can reactivate periodically are ______.

Accepted Answer

A)   chronic latent viruses
B)   oncoviruses
C)   syncytia
D)   inclusion bodies
E)   cytopathicF) All of the above
G) B) and E)

Question 6

Infectious protein particles are called ______.

Accepted Answer

A)   viroids
B)   phages
C)   prions
D)   oncogenic viruses
E)   spikesF) A) and D)
G) C) and D)

Question 7

Viral spikes ________.

Accepted Answer

A)   are always present on enveloped viruses
B)   attach the viral capsid and envelope
C)   allow bacteria to evade host defenses
D)   are derived from host proteins
E)   are for recognition among the various types of virusesF) A) and D)
G) D) and E)

Question 8

Viruses are not ﬁlterable.

Accepted Answer

A) True 
 B)False

Question 9

Viral nucleic acid types include which of the following?

Accepted Answer

A)   Double-stranded DNA
B)   Single-stranded DNA
C)   Double-stranded RNA
D)   Single-stranded RNA
E)   All of the choices are correct.F) All of the above
G) C) and E)

Question 10

Visible, clear, well-deﬁned patches in a monolayer of virus-infected cells in a culture are called ______.

Accepted Answer

A)   patches
B)   buds
C)   plaques
D)   cytopathic effects
E)   pocksF) A) and B)
G) C) and E)

Question 11

A treatment for bacterial infections from the early 20th century has made a comeback; the use of bacterial viruses to eliminate bacterial infections. Which explanation most accurately describes the reason for the return of this treatment?

Accepted Answer

A)   A wide variety of bacteria cause a large percentage of human infections, producing much sickness and death.
B)   Viruses can infect bacteria, transferring pathogenic genes; the viral genes can then be suppressed, causing the bacteria to not replicate viruses.
C)   The attachment structures on the virus and the receptors on the host cells make for exquisite speci?city of viruses for particular bacterial species.
D)   Antibiotic resistance in bacteria is on the increase, so using a different kind of therapy offers an alternative to traditional drugs.E) None of the above
F) B) and C)

Question 12

Uncoating of viral nucleic acid _______.

Accepted Answer

A)   does not occur in bacteriophage multiplication
B)   involves enzymatic destruction of the capsid
C)   occurs during penetration in the multiplication cycle
D)   occurs before replication
E)   All of the choices are correct.F) C) and E)
G) A) and E)

Question 13

A fully formed virus that can cause an infection in a host cell is called a virion.

Accepted Answer

A) True 
 B)False

Question 14

Host range is limited by the _______.

Accepted Answer

A)   type of nucleic acid in the virus
B)   age of the host cell
C)   type of host cell receptors on cell membrane
D)   size of the host cellE) A) and B)
F) A) and C)

Question 15

Which of the following is not a characteristic of a transformed cell?

Accepted Answer

A)   Viral nucleic acid integrated into host DNA
B)   Decreased growth rate
C)   Alterations in chromosomes
D)   Changes in cell surface molecules
E)   Capacity to divide indeﬁnitelyF) B) and C)
G) B) and D)

Question 16

Freshly isolated animal tissue that is placed in a growth medium and allowed to produce a cell monolayer is referred to as a/n _____ cell culture.

Accepted Answer

A)   initial
B)   primary
C)   secondary
D)   continuous
E)   positiveF) D) and E)
G) A) and E)

Question 17

One of the principal viral capsid shapes is a 20-sided ﬁgure with 12 evenly spaced corners referred to as a/an _______ capsid.

Accepted Answer

A)   spiked
B)   complex
C)   icosahedral
D)   helical
E)   buckeyballF) B) and E)
G) C) and D)

Question 18

Which of the following will not support viral cultivation?

Accepted Answer

A)   Live lab animals
B)   Embryonated bird eggs
C)   Primary cell cultures
D)   Continuous cell cultures
E)   All of the choices will support viral cultivation.F) B) and D)
G) C) and E)

Question 19

Viruses are the most common cause of acute infections that do not result in hospitalization.

Accepted Answer

A) True 
 B)False

Question 20

Cells grown in culture form a/an ______.

Accepted Answer

A)   monolayer
B)   bilayer
C)   aggregate
D)   plaqueE) B) and C)
F) A) and D)

Exam 6: Viruses and Prions

Viruses are used to produce vaccines for prevention of certain viral infections.

Correct AnswerverifiedShow Answer

Cells grown in culture form a/an ______.

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Which of the following is not a characteristic of a transformed cell?

Correct AnswerverifiedShow Answer

A treatment for bacterial infections from the early 20th century has made a comeback; the use of bacterial viruses to eliminate bacterial infections. Which explanation most accurately describes the reason for the return of this treatment?

Correct AnswerverifiedShow Answer

Viral nucleic acid types include which of the following?

Correct AnswerverifiedShow Answer

A/an _______ is the protein shell around the nucleic acid core of a virus.

Correct AnswerverifiedShow Answer

Infectious protein particles are called ______.

Correct AnswerverifiedShow Answer

Which of the following is incorrect about prophages?

Correct AnswerverifiedShow Answer

Viruses are not ﬁlterable.

Correct AnswerverifiedShow Answer

Uncoating of viral nucleic acid _______.

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Persistent viruses that can reactivate periodically are ______.

Correct AnswerverifiedShow Answer

Viral spikes ________.

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Viruses are the most common cause of acute infections that do not result in hospitalization.

Correct AnswerverifiedShow Answer

One of the principal viral capsid shapes is a 20-sided ﬁgure with 12 evenly spaced corners referred to as a/an _______ capsid.

Correct AnswerverifiedShow Answer

Which of the following will not support viral cultivation?

Correct AnswerverifiedShow Answer

Freshly isolated animal tissue that is placed in a growth medium and allowed to produce a cell monolayer is referred to as a/n _____ cell culture.

Correct AnswerverifiedShow Answer

Visible, clear, well-deﬁned patches in a monolayer of virus-infected cells in a culture are called ______.

Correct AnswerverifiedShow Answer

Host range is limited by the _______.

Correct AnswerverifiedShow Answer

Tami?u is a common medication given for in?uenza treatment. It works by protecting and blocking sialic acid molecules on the surfaces of host cells and in?uenza virus envelopes as they leave the cell. Which statement re?ects the mechanism of Tami?u's action?

Correct AnswerverifiedShow Answer

A fully formed virus that can cause an infection in a host cell is called a virion.

Correct AnswerverifiedShow Answer

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