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Which of the following processes takes place in the cytoplasm?


A) DNA replication
B) transcription
C) intron removal
D) translation
E) primary mRNA splicing

F) B) and E)
G) A) and E)

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Prokaryote regulate gene expression at which of the following levels?


A) epigenetic inheritance only
B) mRNA translation, mRNA translation and epigenetic inheritance
C) alternative mRNA processing and chromatin compaction
D) mRNA translation and epigenetic inheritance
E) mRNA transcription

F) None of the above
G) D) and E)

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The sequence of amino acids that would result from transcribing and translating a DNA template strand with the bases TACGCTAAT would be


A) Tyr-Ala-Asn.
B) Ile-Ser-Val.
C) no peptide would be made; the first codon means "stop."
D) Met-Arg-Leu.
E) Tyr-Ser-Val.

F) All of the above
G) A) and B)

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Failure to remove introns from a primary mRNA would most likely cause


A) irregularities in transcription.
B) abnormal translation.
C) DNA to mutate.
D) DNA replication to fail.
E) transcription to terminate early.

F) C) and D)
G) A) and D)

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The sequence of the mRNA that would result from transcribing a DNA template strand with the bases TACGCTAAT would be


A) AUGCGAUUA.
B) AUUAGCGUA.
C) UACGCUAAU.
D) UAAUCGCAU.
E) ATGCGATTA.

F) A) and B)
G) B) and D)

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The repressor protein used by Escherichia coli to control the lac operon is coded for by a gen e located within the operon.

A) True
B) False

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The term semiconservative refers specifically to


A) DNA replication.
B) translation.
C) transcription.
D) transformation.
E) RNA processing.

F) C) and E)
G) D) and E)

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Which process requires the participation of all three types of RNA?


A) transcription
B) translation
C) RNA processing
D) replication
E) complementary base pairing

F) A) and C)
G) C) and D)

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DNA replication is called semiconservative because


A) one of the resulting DNA molecules is comprised of entirely old DNA and one is comprised of entirely new DNA.
B) each resulting DNA molecules is comprised of one new DNA strand and one old strand.
C) both of the resulting DNA molecules are comprised of entirely new strands of nucleotides.
D) no extra nucleotides are incorporated into the replicated DNA molecules.
E) the sequence of nucleotides in one strand is conserved, whereas the new DNA molecule consists of a unique sequence of nucleotides.

F) B) and D)
G) B) and C)

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For a DNA strand composed of the sequence AGT in the 5' to 3' direction, the free phosphate is on the ________ nucleotide and the free hydroxyl is on the ________ nucleotide.


A) T; A
B) A; G
C) A; A
D) G; T
E) A; T

F) A) and E)
G) B) and C)

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mRNA is processed in the cytoplasm before being used in protein synthesis.

A) True
B) False

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For a DNA strand that is two nucleotides long, how many different sequences are possible?


A) 2
B) 4
C) 8
D) 16
E) 64

F) A) and B)
G) C) and E)

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Transcription activators are different from transcription factors in that


A) transcription activators are required for RNA polymerase binding, while transcription factors slow RNA polymerase binding.
B) transcription factors assist RNA polymerase binding while transcription activators accelerate the mRNA processing.
C) transcription activators slow transcription, while transcription factors accelerate transcription.
D) transcription factors prevent RNA polymerase binding, while transcription activators assist RNA polymerase binding.
E) transcription factors are required for RNA polymerase binding, while transcription activators accelerate transcription.

F) A) and D)
G) B) and C)

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Female mammals form Barr bodies because


A) compacting the chromatin of one of their X chromosomes allows them to inactivate it and produce the same amount of gene product as a male.
B) unpacking one of their X chromosomes allows them to produce more gene product than a male.
C) compacting the chromatin in one of their X chromosomes allows them to conserve histone proteins.
D) compacting the chromatin in one of their X chromosomes allows them to produce more gene product than a male from the other X chromosome.
E) unpacking one of their X chromosomes allows them to choose which allele they wish to express, which a male cannot do.

F) A) and D)
G) B) and C)

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The three steps that are required for DNA replication are


A) unwinding, complementary base pairing, and joining.
B) base doubling, unwinding, and joining.
C) complementary base pairing, transcription, and translation.
D) unwinding, transcription, and translation.
E) unwinding, base doubling, and base pairing.

F) A) and B)
G) B) and E)

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Histone displacement is necessary for transcription to occur in euchromatin.

A) True
B) False

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Which base is found in DNA, but not in RNA?


A) cytosine
B) uracil
C) thymine
D) adenine
E) guanine

F) A) and E)
G) A) and D)

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What would be the most likely result on the regulation of the lac operon from a nonfunctional repressor protein?


A) transcription of the lactose metabolizing genes, even when lactose is absent
B) no transcription of the lactose metabolizing genes, even when lactose is present
C) binding of the repressor protein to the operator, even when lactose is present
D) binding of the repressor protein to the regulatory gene in both the presence and absence of lactose
E) no transcription of the regulatory gene, even in the presence of lactose

F) D) and E)
G) C) and D)

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The unpacking of heterochromatin into euchromatin does not immediately result in DNA transcription because


A) Barr bodies are still present.
B) histones still block the binding of RNA polymerase to the promoter.
C) euchromatin is always transcriptionally inactive.
D) transcription factors still block the binding of RNA polymerase to the promoter.
E) heterochromatin contains DNA with accessible promoters.

F) A) and B)
G) All of the above

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Using three bases to represent each amino acid in a polypeptide


A) ensures that all amino acids are represented at least once by the code.
B) ensures that other organisms can read the code too.
C) ensures that DNA can replicate properly.
D) prevents the wrong amino acid from being incorporated into a protein.
E) prevents early termination of transcription.

F) C) and D)
G) B) and D)

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