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The spontaneous opening of sodium channels marks the beginning of ____ of a myocardial cell.


A) depolarization
B) repolarization
C) hyperpolarization
D) isopolarization
E) afterpolarization

F) A) and E)
G) C) and D)

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During the ejection phase of the cardiac cycle, blood exits the left ventricle through the


A) aorta.
B) coronary sinus.
C) pulmonary vein.
D) superior vena cava.
E) pulmonary trunk.

F) B) and C)
G) A) and C)

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Chemoreceptors sensitive to blood carbon dioxide levels are primarily located in the


A) medulla oblongata.
B) carotid arteries.
C) right atrium.
D) left ventricle.
E) jugular veins.

F) A) and D)
G) B) and C)

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A direct connection between arteries is called a/an


A) auricle.
B) sulcus.
C) sinus.
D) anastamosis.

E) A) and D)
F) All of the above

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All cardiac veins empty into the _________, which then empties into the _______.


A) coronary sinus; left atrium
B) coronary sinus; right atrium
C) great cardiac vein; right atrium
D) great cardiac vein; superior vena cava
E) inferior vena cava; left atrium

F) C) and D)
G) None of the above

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What is the foramen ovale?


A) An opening between the right and left atria in the embryo and fetus.
B) An opening between the right and left ventricles in the embryo and fetus.
C) An oval hole in the pericardium in the embryo and fetus.
D) An opening between the pulmonary trunk and aorta in the embryo and fetus.

E) A) and C)
F) A) and D)

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A

Calcium-induced calcium release occurs when


A) calcium from the sarcoplasmic reticulum stimulates the movement of calcium into the cell through the plasma membrane.
B) calcium is released from both the sarcoplasmic reticulum and the cardiac muscle cell.
C) the eflux of calcium from the cell results in depolarization.
D) calcium entering through the plasma membrane stimulates release of calcium from the sarcoplasmic reticulum.

E) C) and D)
F) All of the above

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Within normal limits, an increase in preload leads to


A) an increase in cardiac output and force of left ventricular contraction.
B) a decrease in cardiac output and force of left ventricular contraction.
C) an increase in cardiac output and a decrease in force of left ventricular contraction.
D) a decrease in cardiac output and an increase in the force of left ventricular contraction.
E) a decrease in stroke volume and heart rate.

F) A) and B)
G) A) and C)

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The period of time in which the myocardium is insensitive to further stimulation is called the


A) absolute refractory period.
B) hyperpolarization period.
C) AV period.
D) SA period.
E) ectopic focus.

F) B) and D)
G) B) and C)

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A

Which of the following phrases would apply to cardiac muscle cells?


A) are organized in parallel columns or bundles
B) contain actin but no myosin
C) develop a significant oxygen debt during systole
D) are multinucleated like skeletal muscle cells
E) possess special cell-to-cell contacts called intercalated discs

F) A) and C)
G) A) and D)

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The right side of the heart receives blood from the body and pumps through _________ circulation to the lungs.


A) hepatic
B) pulmonary
C) peripheral
D) systemic

E) C) and D)
F) None of the above

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Which of the following is NOT true about the heart?


A) The heart is about the size of a closed fist.
B) The heart is located in the mediastinum.
C) The apex of the heart is directed superiorly and to the left.
D) Knowing the heart's position is important for effective CPR.

E) A) and B)
F) A) and C)

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Which of the following layers forms the bulk of the heart wall?


A) epicardium
B) pericardium
C) endocardium
D) myocardium
E) visceral pericardium

F) C) and D)
G) All of the above

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D

The epicardium


A) covers the surface of the heart.
B) lines the walls of the ventricles.
C) is known as the fibrous pericardium.
D) attaches inferiorly to the diaphragm.
E) is also called endocardium.

F) A) and D)
G) B) and E)

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Which vessels transport blood to the right and left lungs?


A) aorta
B) right atrium
C) pulmonary trunk
D) pulmonary arteries
E) pulmonary veins

F) All of the above
G) A) and B)

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The baroreceptor reflex would cause which of the following events to occur if the reflex was caused by an increase in blood pressure?


A) increased parasympathetic stimulation of the heart
B) increased heart rate
C) increased cardiac output
D) increased force of contraction
E) increased sympathetic stimulation of the heart

F) B) and D)
G) A) and D)

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Calcium channel blockers are frequently used to


A) increase the heart rate.
B) treat tachycardia or other arrhythmias.
C) speed up conduction of impulses through the AV node.
D) slow the closing of potassium ion channels.
E) treat bradycardia and low blood pressure.

F) A) and E)
G) B) and C)

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Which of the following would result from a reduced function of the sodium channels in the SA node?


A) depolarization would be delayed
B) the heart rate would decrease
C) repolarization would not occur
D) a shortened plateau phase
E) depolarization would be delayed and the heart rate would decrease

F) A) and E)
G) None of the above

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Ventricular contraction begins at the


A) AV bundle.
B) apex of the heart.
C) base of the heart.
D) superior portion of the interventricular septum.
E) top of the ventricles.

F) D) and E)
G) A) and B)

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During the isovolumetric contraction period of the cardiac cycle,


A) AV and semilunar valves are closed.
B) the atria are contracted.
C) ventricular volume increases.
D) blood is pumped into the large arteries.
E) pressure in the ventricles decreases.

F) A) and B)
G) A) and C)

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