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The inflammatory response includes a decrease in the permeability of capillaries to prevent excessive blood loss after injury.

A) True
B) False

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Which is not an action of interferon


A) It stimulates macrophages and NK cells to destroy virus-infected cells.
B) It triggers synthesis of enzymes that destroy viral nucleic acids.
C) It signals the immune system that the secreting cell is part of the body and so should not be attacked.
D) It binds to receptors of neighboring cells preventing them from being infected.

E) B) and C)
F) A) and D)

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MHC class I molecules on a cell allow it to interact with


A) natural killer cells.
B) cytotoxic T-lymphocytes.
C) helper T-lymphocytes.
D) CD8+B-lymphocytes.

E) B) and D)
F) A) and B)

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The second signal during cytotoxic T-lymphocyte activation involves stimulation of the cell by interleukin 2 released by helper T-lymphocytes.

A) True
B) False

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Which type of antibody is formed in response to parasitic infections and allergies,and has the effect of activating mast cells and basophils


A) IgA
B) IgB
C) IgD
D) IgE
E) IgG

F) A) and E)
G) A) and C)

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Exudate formation delivers substances to eliminate injurious agents,and the resulting increase in interstitial hydrostatic pressure leads to increased fluid uptake by lymphatic capillaries.

A) True
B) False

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Some antibodies cross the placenta.

A) True
B) False

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Nonspecific immunity is another name for


A) adaptive immunity.
B) innate immunity.
C) cell-mediated immunity.
D) acquired immunity.

E) C) and D)
F) A) and C)

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A secondary response to an infectious agent has a _______ latent phase than a primary response has.


A) longer
B) shorter

C) A) and B)
D) undefined

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Why are functions of T-lymphocytes referred to as "cell-mediated" immunity


A) Because T-lymphocytes are cells and not just plasma proteins
B) Because T-lymphocytes work against antigens associated with cells
C) Because T-lymphocytes work only against single-celled infectious agents
D) Because T-lymphocytes must activate other classes of cells in order to have any effect

E) A) and B)
F) A) and C)

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B

Inflamed tissue feels warm due to


A) increased blood flow and increased metabolic activity.
B) the margination of white blood cells.
C) chemotaxis and defervescence.
D) activation of complement by binding of C-reactive protein to bacterial carbohydrates.

E) C) and D)
F) None of the above

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Active immunity requires


A) the transfer of antibodies from another individual.
B) direct encounter with the antigen.
C) that an active virus be used in a vaccine.
D) that all immune responses to the pathogen result in symptoms of illness.

E) A) and B)
F) A) and C)

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When part of the immune system recognizes and binds to a foreign molecule,the part of the molecule to which binding occurs is called the epitope or _________ determinant.

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Which part of an antibody attaches to an antigen


A) The hinge region
B) The constant region
C) The heavy chain
D) The variable region

E) A) and B)
F) A) and D)

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D

The most prevalent antibody in blood and lymph is


A) IgA.
B) IgC.
C) IgD.
D) IgE.
E) IgG.

F) A) and E)
G) D) and E)

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Activation of lymphocytes occurs in


A) primary lymphatic structures.
B) secondary lymphatic structures.
C) tertiary lymphatic structures.
D) effectors such as muscles and glands.

E) None of the above
F) All of the above

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In positive selection of T-lymphocytes,those cells that


A) bind self antigens are eliminated.
B) can bind MHC survive.
C) bind to self antigens survive.
D) bind to MHC class II are eliminated.

E) B) and C)
F) C) and D)

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What are considered the effectors of humoral immunity


A) Helper T-lymphocytes
B) Cytotoxic T-lymphocytes
C) Antibodies
D) Macrophages
E) Natural killer cells

F) A) and B)
G) B) and D)

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C

Helper T-lymphocyte activation involves MHC class I,whereas cytotoxic T-lymphocyte activation involves MHC class II.

A) True
B) False

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Cytotoxic T-lymphocytes that have killed a foreign cell may transform into


A) memory B-lymphocytes.
B) natural killer cells.
C) plasma cells.
D) helper T-lymphocytes.
E) None of the choices is correct.

F) B) and C)
G) D) and E)

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