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In addition to dendritic cells and macrophages,B cells can also act as antigen-presenting cells.  This occurs when ________.


A) the antigen is a molecule with a simple,repeating structure and evokes an immune response as a T-cell-independent antigen
B) the B cell engulfs the antigen and presents it to the T helper cell
C) the B cell engulfs the antigen and presents it to the T cytotoxic cell
D) the antigen binds to the B cell and after processing,it is presented to the dendritic cells and macrophages

E) A) and D)
F) C) and D)

Correct Answer

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Class I MHC genes code for ________.


A) certain secreted complement components
B) self receptors recognized by T lymphocytes
C) all HLA antigens
D) receptors located primarily on macrophages and B cells
E) All of the choices are correct.

F) B) and E)
G) D) and E)

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An RN working in a general medical-surgical unit is caring for a 57-year-old female with a bladder infection. Two weeks prior to hospitalization, the patient was experiencing slight burning upon urination. She self-treated by increasing her intake of fluids, but her symptoms continued to worsen. One week later, she developed generalized abdominal pain and a fever. She presented to the hospital when the pain became unbearable and fever reached 104°F. She was admitted to the medical-surgical unit and started on multiple IV antibiotics with concern that she could be developing a kidney infection. -Knowing that the causative organism for this patient's urinary tract infection,E.coli,has a lipopolysaccharide cell wall,which cells are being activated by this infection?


A) T helper cells
B) T cytotoxic cells
C) Natural killer cells
D) B cells

E) A) and D)
F) A) and B)

Correct Answer

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D

The molecular fragment on an antigen molecule that a lymphocyte recognizes and responds to is called a(n) ________.


A) epitope
B) hapten
C) antigen binding site
D) variable region
E) None of the choices are correct.

F) B) and D)
G) B) and E)

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A 6-year-old male is brought to his pediatrician's office with chickenpox. He has had symptoms for one week, and his mother is concerned about the patient's 8-year-old sister because she had a long, painful chickenpox infection 2 years prior. Of note, the patient was not vaccinated against chickenpox because his parents did not think it was a serious enough virus to warrant the pain of the injection. -After his recovery from chickenpox,which lymphocytes will keep this patient from becoming infected again? 


A) T helper cells
B) Natural killer cells
C) T memory cells
D) B cells

E) B) and D)
F) B) and C)

Correct Answer

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Clonal selection can be stimulated by foreign or self antigens.

A) True
B) False

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Which of the following is not a target for TC cells?


A) Bacteria
B) Virus-infected cells
C) Cancer cells
D) Human transplanted liver
E) Pig transplanted heart

F) B) and C)
G) D) and E)

Correct Answer

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Which of the statements below represents the correct order in the development of an immune response?


A) Development and clonal deletion; antigen presentation; lymphocyte challenge; lymphocyte response
B) Antigen presentation; development and clonal deletion; lymphocyte challenge; lymphocyte response
C) Lymphocyte challenge; antigen presentation; development and clonal deletion; lymphocyte response
D) Development and clonal deletion; lymphocyte challenge; antigen presentation; lymphocyte response

E) A) and B)
F) A) and C)

Correct Answer

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An RN working in a general medical-surgical unit is caring for a 57-year-old female with a bladder infection. Two weeks prior to hospitalization, the patient was experiencing slight burning upon urination. She self-treated by increasing her intake of fluids, but her symptoms continued to worsen. One week later, she developed generalized abdominal pain and a fever. She presented to the hospital when the pain became unbearable and fever reached 104°F. She was admitted to the medical-surgical unit and started on multiple IV antibiotics with concern that she could be developing a kidney infection. -Which part of the IgG molecule will bind with the E.coli antigen?


A) Fab
B) Fc
C) Complement binding site
D) Cellular binding site

E) B) and C)
F) All of the above

Correct Answer

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A

Antibody molecules circulate in lymph,blood,and tissue fluids.

A) True
B) False

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Gamma globulin can be given as immunotherapy to confer artificial passive immunity.

A) True
B) False

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Helper T cells ________.


A) secrete antibodies
B) function in allergic reactions
C) directly destroy target cells
D) suppress immune reactions
E) activate B cells and other T cells

F) A) and B)
G) A) and C)

Correct Answer

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Antigens that elicit allergic reactions are called ________.


A) superantigens
B) heterophilic antigens
C) allergens
D) autoantigens
E) None of the choices are correct.

F) C) and E)
G) A) and D)

Correct Answer

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Killed or inactivated vaccines are prepared by ________.


A) removal of virulence genes from the microbe
B) treatment with formalin,heat,or radiation
C) passage of the pathogen through unnatural hosts or tissue culture
D) long-term subculturing of the microbe
E) All of the choices are correct.

F) A) and B)
G) B) and C)

Correct Answer

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An example of natural active immunity would be ________.


A) chickenpox infection followed by lifelong immunity
B) chickenpox vaccine,which triggers extended immunity to chickenpox
C) giving a person immune serum globulins to chickenpox virus after exposure to the disease
D) a fetus acquiring maternal IgG to the chickenpox virus across the placenta
E) None of the choices are correct.

F) All of the above
G) A) and D)

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A 2-week-old infant is brought to a family practice office for a scheduled visit. The parents appear anxious, as this is their first child. They express multiple concerns to the nurse about their son's sleep patterns, feeding, and crying. The RN provides empathetic listening and education to calm their fears, and they are receptive to the teaching. When the RN discusses vaccination with the parents, they refuse to vaccinate their son because they have heard vaccines can cause autism in children. -Which of the following statements is not true concerning vaccines?


A) They consist of killed or inactivated cells.
B) They consist of live but weakened microbes.
C) It is possible to be allergic to vaccine preparations.
D) Autism only happens in rare instances of vaccination.

E) None of the above
F) B) and C)

Correct Answer

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Class II MHC genes code for ________.


A) certain secreted complement components
B) self receptors recognized by T lymphocytes
C) all HLA antigens
D) receptors located primarily on macrophages and B cells
E) All of the choices are correct.

F) A) and B)
G) B) and C)

Correct Answer

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Human B lymphocytes mature in an intestinal region called the bursa.

A) True
B) False

Correct Answer

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Cytotoxic T cells ________.


A) are directly activated by antigens
B) lack specificity for antigen.
C) secrete granzymes and perforins that damage target cells
D) secrete interleukin-2 to stimulate B and T cells
E) All of the choices are correct.

F) B) and E)
G) A) and B)

Correct Answer

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C

A 6-year-old male is brought to his pediatrician's office with chickenpox. He has had symptoms for one week, and his mother is concerned about the patient's 8-year-old sister because she had a long, painful chickenpox infection 2 years prior. Of note, the patient was not vaccinated against chickenpox because his parents did not think it was a serious enough virus to warrant the pain of the injection. -Which of the following explanations correctly represents how this patient could have been protected from chickenpox infection? 


A) He would not have been infected if he were breastfed as a baby because he would have passive natural immunity.
B) He would not have been infected if his mother had gamma globulin administered during pregnancy because he would have passive artificial immunity.
C) He could have been protected from infection if he received active artificial immunity through the form of a vaccine.
D) He may have a primary immunodeficiency disease because healthy humans are not typically infected with chickenpox.

E) A) and B)
F) B) and D)

Correct Answer

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