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Research published in January 2017 presented an estimate of the prevalence of HPV infection in American males at 45%.Adult males are an unvaccinated population.What are the consequences of HPV infection in males?


A) Males with HPV have a significantly higher likelihood of developing prostate cancer.
B) HPV-infected males should also be screened for gonorrhea, as the two often co-infect.
C) There are no long-term consequences; a course of antiviral medication will clear up the infection.
D) Males can develop genitourinary tract cancer from HPV infection.

E) B) and D)
F) A) and D)

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Candida albicans is a ______.


A) protozoan
B) bacterium
C) fungus
D) helminth

E) A) and B)
F) A) and C)

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The most common mode of disease transmission in UTIs is ______.


A) opportunism
B) endogenous transfer
C) fomites
D) aerosol
E) indirect contact

F) B) and D)
G) C) and D)

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Herpes simplex-2 (HSV-2) causes


A) genital lesions.
B) intensely sensitive vesicles on or near the genitals.
C) symptoms that include urethritis, cervicitis, and itching.
D) infection in neonates that contact lesions in the birth canal.
E) All of the choices are correct.

F) A) and C)
G) B) and D)

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The pathogenesis of Neisseria gonorrhoeae is dependent upon phase variation.Which of the following statements concerning phase variation is incorrect?


A) Phase variation involves alterations to the structure of the fimbriae.
B) Phase variations results from genetic rearrangements in the Neisseria chromosome.
C) Phase variation allows Neisseria cells to escape immune detection.
D) Phase variation results in Neisseria cells adopting a pleomorphic morphology.

E) A) and D)
F) A) and C)

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The antivirals used for herpes simplex infections have the ability to completely destroy the virus and permanently cure the latent infection.

A) True
B) False

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Group B Streptococcus infections can cause serious infections in infants through vertical transmission.

A) True
B) False

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A woman is much more likely than a man to contract a UTI.Which of the following practices would best reduce her chances of getting a UTI?


A) Daily antibiotic dose
B) Not wearing tight-fitting clothes
C) Wiping with toilet paper in a front-to-back direction
D) Using birth control pills

E) A) and B)
F) A) and C)

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Prostatitis and urinary tract infections (UTIs) are alike in that


A) treatment will minimize the symptoms but will never completely eliminate the disease.
B) untreated cases may complicate by infecting the kidneys.
C) women are far more susceptible to both infections than men.
D) both result from the transfer of normal biota from the GI tract.

E) B) and C)
F) A) and D)

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The population most likely to be affected by catheter-associated urinary tract infections is


A) elderly women in a nursing home.
B) women who have recently delivered a baby by caesarean section.
C) urban sex workers.
D) women who abuse intravenous drugs.

E) None of the above
F) A) and D)

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Which of the following characteristics can distinguish vaginitis and vaginosis?


A) Causative agent
B) Presence of vaginal inflammation
C) Presence of discharge
D) All of the choices are correct.

E) All of the above
F) A) and B)

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During which stage of syphilis does fever, lymphadenopathy, and a red to brown rash occur?


A) Primary
B) Secondary
C) Tertiary
D) Latent

E) A) and D)
F) All of the above

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The primary virulence factor of Neisseria gonorrhoeae is ______.


A) a hemolysin
B) an endotoxin
C) fimbriae
D) an exotoxin
E) a protease

F) D) and E)
G) A) and D)

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Which of the following statements regarding leptospirosis in incorrect?


A) The causative organism infects the kidneys, liver, brain, and eyes.
B) Humans acquire it by contact with abraided skin or mucous membranes.
C) It can be transmitted by animal bites.
D) The causative organism is a spirochete.
E) It is most common in cattle, horses, pigs, and dogs.

F) A) and E)
G) B) and E)

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You, a 29 year old sexually active male, have discovered some small vesicles on the penis.They are fluid-filled, red, and very painful.This is the second time that you have seen this.The first time around, about 2 months ago, you saw them but managed to ignore them.The lesions went away--no doctor, no treatment.But here they are again.You think that perhaps you picked up this infection six months ago, the last time that you had sex.Identify the likely infection.


A) Chlamydia
B) HSV-2 infection
C) Candidiasis
D) Syphilis
E) HSV-1 infection

F) A) and D)
G) A) and C)

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Trichomonas vaginalis


A) does not produce cysts.
B) infection is generally asymptomatic in males.
C) causes vaginitis in females.
D) has four flagella and an undulating membrane.
E) All of the choices are correct.

F) A) and B)
G) A) and C)

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Even after a positive test for a microbial cause, chronic prostatitis is unresponsive to antibiotic therapy.Why might this be the case?


A) Mixed species biofilms are hard to eliminate with antibiotics.
B) The side effects of the drug are too great.
C) It is a viral infection.
D) The infection is sporadic.

E) A) and B)
F) All of the above

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Which of the following statements regarding prostatitis is incorrect?


A) It is caused by GI tract biota.
B) It is accompanied by pain and frequent, difficult urination.
C) It can be chronic or acute.
D) The specific causative agent is readily cultured and identified.

E) None of the above
F) A) and D)

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Treponema pallidum


A) has humans as the sole reservoir.
B) can cross the placenta.
C) has a hooked tip to attach to epithelium.
D) is transmitted by direct sexual contact.
E) All of the choices are correct.

F) A) and D)
G) D) and E)

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Which of the following statements regarding the Chlamydia life cycle is incorrect?


A) The elementary body is the infectious stage of Chlamydia.
B) Elementary bodies are released from the host cell to continue the infectious cycle.
C) Elementary bodies differentiate into reticulate bodies in the cell nucleus.
D) Reticulate bodies multiple by binary fission.

E) A) and D)
F) None of the above

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