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Which of the following statements is not true of enteroinvasive


A) Blood and pus are found in the stool.
B) High fever is present.
C) It makes no heat-labile or heat-stable exotoxins.
D) Prompt treatment with a broad-spectrum antibiotic is essential to recover from an infection.
E) It invades the gut mucosa.

F) B) and C)
G) A) and E)

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Vibrio cholerae can be readily isolated and identified in the laboratory from stool samples by


A) dark-field microscopy looking for motility.
B) its ability to grow at high temperature and produce zones of clearing on blood agar.
C) its robust chemotactic response to the presence of chitin.
D) growth on selective media followed by PCR of its 16S rRNA gene.

E) All of the above
F) A) and B)

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The primary viral cause of chronic diarrhea globally is ______.


A) rotavirus
B) Cryptosporidium
C) arbovirus
D) adenovirus
E) norovirus

F) D) and E)
G) A) and E)

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Enteropathogenic E.coli (EPEC) causes gut effacement with shiga toxin.

A) True
B) False

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Escherichia coli infections


A) are often transmitted by fecal contaminated water and food.
B) include EIEC that destroys gut mucosa.
C) involve enterotoxin in traveler's diarrhea.
D) are self-limiting with the only treatment being rehydration.
E) All of the choices are correct.

F) A) and E)
G) B) and E)

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Which of the following is not a virulence factor associated with helminths?


A) Degradative enzymes to damage host tissue
B) Specialized structures for attachment to host tissues
C) Secretion of toxins
D) Thick cuticle to escape detection from the host immune system

E) C) and D)
F) A) and B)

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Which of the following statements is not true regarding Clostridium difficile?


A) Infection is precipitated by broad-spectrum antibiotic therapy.
B) It produces "rice-water" stools.
C) It is part of the normal intestinal biota.
D) It is also called pseudomembranous colitis.
E) It is a gram-positive, endospore-forming rod.

F) B) and E)
G) B) and C)

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In the absence of dietary carbohydrates, bacteria do not cause tooth decay.

A) True
B) False

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There are vaccines for immunity to the Hepatitis B virus.

A) True
B) False

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A common food intoxication is caused by enterotoxin-producing strains of ______.


A) Streptococcus pyogenes
B) Staphylococcus saprophyticus
C) Streptococcus agalactiae
D) Staphylococcus aureus
E) Staphylococcus epidermidis

F) A) and E)
G) All of the above

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Your son has not had the MMR vaccine (measles, mumps, rubella) because you are apprehensive about vaccines and their side effects.Your sister says that you are setting him up for a potentially damaging scenario.Which argument has the great scientific validity and why?


A) Your sister is correct.Even if your son does not get the mumps now when he is young, but gets the infection later in life, there is a possibility of severe side effects.
B) Your sister is correct in her warnings.If your son gets a severe case of mumps, he will likely develop a fatal secondary infection.
C) You are correct in protecting your son.If you can keep him from getting mumps when young, it is no longer a problem.It is simply a childhood disease.
D) You are correct to be apprehensive because vaccines have been the cause of autism in children.

E) C) and D)
F) All of the above

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Which of the following statements regarding fecal transplant is correct?


A) Donors and recipients must be carefully matched to prevent an immune reaction in the recipient.
B) The goal is to completely eradicate Clostridium difficile from a patient's gut microbiota and replace it with a healthy community.
C) Fecal matter must be carefully disinfected and screened for viruses, cysts, and endospores before transfer to a recipient patient.
D) This treatment is designed to jump-start the intestinal microbiota after an infection with Clostridium difficile resuts in acute diarrhea.

E) A) and D)
F) B) and C)

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Paramyxoviruses evade the host immune system by


A) infecting only red blood cells.
B) entering new cells by inducing syncytia formation.
C) producing an inhibitor specific for lymphocyte receptors.
D) a display of host antigens on its surface.

E) A) and B)
F) All of the above

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It is now past the normal dinner time, but you do not even want to think about food.Only diarrhea, abdominal cramps, and vomiting are on your mind.This all started a few hours ago after having a ham sandwich for lunch purchased from a street vendor.With your microbiology knowledge, you surmise that it is a Staphylococcus aureus-related disorder.Why do you think this?


A) Staphylococcus aureus is the most common cause of gastrointestinal disease.
B) The toxin produced by Staphylococcus aureus was already in the ham, so the symptoms can occur quickly.
C) Ham is notorious for being contaminated with Staphylococcus aureus bacteria.
D) Only Staphylococcus aureus infection causes vomiting, along with cramps and diarrhea.

E) C) and D)
F) None of the above

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All of the following diseases can be transmitted by drinking contaminated water except ______.


A) trichinosis
B) campylobacter
C) cyclosporiasis
D) giardiasis
E) cryptosporidiosis

F) A) and E)
G) B) and D)

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Identify the mismatch in the following list of helminths and their common names.


A) Schistosoma mansoni; blood fluke
B) Ascaris lumbricoides; intestinal roundworm
C) Opisthorchis sinensis; liver fluke
D) Trichuris trichiura; whipworm
E) Taenia solium; pinworm

F) B) and D)
G) A) and B)

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GALT refers to


A) defenses of the GI tract: Gut microbes, Adenoids, Lysozyme, Tonsils.
B) Gut-Associated Lymphoid Tissue.
C) Gingival Adhesive Labile Toxin, a virulence factor for gingivitis.
D) sterile organs of the GI tract: Gingiva, Appendix, Large intestine, Tonsils.

E) C) and D)
F) B) and D)

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From the surface to the interior of a tooth, the tissues in order are


A) enamel, pulp, and dentin.
B) pulp, dentin, and enamel.
C) dentin, pulp, and enamel.
D) enamel, dentin, and pulp.
E) dentin, enamel, and pulp.

F) A) and E)
G) All of the above

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Just back from a trip to South America, you now have a severe diarrheal illness.Your symptoms, other than diarrhea, are pain, cramps, some fecal blood, and fever.These are symptoms of many of the gastrointestinal diseases, so that information does not help you or the doctors identify the infectious agent.Your doctor wants to send a fecal sample to the microbiology lab for them to look at it under the light microscope.Based upon this protocol selection, the physician believes that you have ______.


A) salmonellosis
B) hepatitis A
C) rotavirus
D) cholera
E) amoebiasis

F) A) and E)
G) B) and C)

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Mumps causes permanent sterility in young male adults.

A) True
B) False

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