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Pertussis has been making a big comeback in the last few years, after being on the decline for quite a long time.Why is this?


A) Few people have ever received pertussis vaccines because there have been links to autism.
B) The strain of Bordetella pertussis that is now the major cause of pertussis is much more virulent than earlier strains.
C) The pertussis vaccine does not seem to protect for a lifetime, so those who received the vaccine as kids may become susceptible in adulthood.
D) People eat so much refined sugars and starches that our immune systems are much weaker, thereby not being able to adequately protect against pertussis bacteria.

E) B) and C)
F) None of the above

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All of the following pertain to tuberculosis except


A) live bacilli can remain dormant in the lungs and reactivate later in life.
B) symptoms of active TB include low-grade fever, coughing, fatigue, weight loss, and night sweats.
C) lung infection can disseminate to many other organs in extrapulmonary TB.
D) the BCG vaccine is used in other countries.
E) antimicrobials cannot treat and cure tuberculosis.

F) None of the above
G) B) and D)

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What features of the respiratory system protect it from infection?


A) Nasal hairs
B) Cilia
C) Mucus
D) Macrophages
E) All of the choices are correct.

F) A) and B)
G) None of the above

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The high mortality rate for patients with MDR-TB and XDR-TB is due in part because of the severe side effects from the daily multidrug regimen and the stimulation of a strong cell-mediated immune response.

A) True
B) False

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Untreated streptococcal pharyngitis can lead to all of the following except _______.


A) scarlet fever
B) otitis media
C) rheumatic fever
D) glomerulonephritis

E) A) and B)
F) A) and C)

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Hantavirus has all of the following characteristics except


A) the reservoir is human carriers.
B) it is a zoonosis.
C) symptoms are abrupt fever, lung edema, respiratory distress, and hypotension.
D) it is transmitted by aerosol transmission from rodent excreta.
E) the first U.S.outbreak occurred in 1993 in the southwest.

F) B) and D)
G) B) and C)

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Legionella pneumophila


A) requires special lab growth media.
B) often lives intracellularly in amoebas.
C) causes fever, cough, and diarrhea.
D) always causes a severe pneumonia.

E) A) and B)
F) A) and C)

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Organisms other than bacteria make up the microbiota; non-bacterial microbes that occupy the respiratory tract include ________.


A) Pseudomonas
B) Candida
C) Prevotella
D) Acinetobacter
E) Staphylococcus

F) B) and E)
G) A) and B)

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Hantavirus is transmitted by which of the following ways?


A) Aerosolized droplets from human to human
B) Directly from the saliva of a deer mouse after being bitten
C) From a mosquito that first bites a deer mouse, and then bites a human
D) Aerosolized particles of deer mouse feces, urine, or saliva
E) Via the oral-fecal route when deer mouse feces contaminate drinking water

F) A) and B)
G) D) and E)

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A factor in the development of multidrug-resistant strains of Mycobacterium tuberculosis is that


A) multiple antibiotics must be taken in the daily regimen.
B) the daily multidrug regimen lasts up to 9 months.
C) many TB patients live in less-than ideal circumstances.
D) All of the above contribute to the development of resistant strains of Mycobacterium tuberculosis.

E) B) and C)
F) C) and D)

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Formation of a pseudomembrane in the back of the throat is seen in cases of _______.


A) diphtheria
B) pharyngitis
C) tuberculosis
D) pertussis
E) SARS

F) A) and D)
G) C) and E)

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The major virulence factor of Corynebacterium diphtheriae that causes serious systemic effects is its ______.


A) capsule
B) metachromatic granules
C) exotoxin
D) endospores
E) endotoxin

F) A) and D)
G) All of the above

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Respiratory syncytial virus


A) causes serious disease in infants 6 months old or younger.
B) uses the nasopharynx as its main replication site.
C) can be treated with the antiviral aerosol ribavirin.
D) has symptoms of dyspnea and rales.
E) All of the choices are correct.

F) A) and E)
G) A) and B)

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The bright red rash and fever of scarlet fever is due to _______.


A) enterotoxins
B) hemolysins
C) toxic shock syndrome toxin
D) exfoliative toxin
E) erythrogenic toxin

F) C) and E)
G) A) and D)

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Symptoms of influenza include


A) nasal discharge, mild fever, and absence of cough.
B) fever, diarrhea, and vomiting.
C) fever, myalgia, sore throat, cough, and nasal discharge.
D) fever, sore throat, rash, and cough.
E) fever and pneumonia.

F) A) and B)
G) B) and D)

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The tubercles formed in primary tuberculosis are caused by an influx of ______.


A) neutrophils
B) basophils
C) mononuclear cells
D) polymorphonuclear leukocytes
E) antibodies

F) B) and D)
G) A) and D)

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Influenza is predominantly transmitted by the fecal-oral route.

A) True
B) False

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The major reservoir for the hantavirus is the deer mouse.

A) True
B) False

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Which of the following is not true of whooping cough?


A) Secondary infections can occur during the convalescent phase.
B) It is caused by a small, aerobic, gram-negative rod.
C) Incubation period is 3-21 days.
D) Cold-like symptoms are common for the paroxysmal stage.
E) An uncontrollable cough occurs during the paroxysmal stage.

F) B) and E)
G) A) and B)

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Which disease involves transmission by aerosolized water from whirlpool spas, air conditioners, cooling towers, and supermarket vegetable misters?


A) Legionellosis
B) Pertussis
C) Brucellosis
D) Plague
E) Traveler's diarrhea

F) A) and E)
G) A) and D)

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