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Toxoplasma gondii infects the brain, as do many other pathogens.However, Toxoplasma differs from other pathogens in that it


A) causes tumor formation in the brain.
B) causes destruction of brain tissue.
C) always kills the host.
D) manifests in behavioral changes in the host.

E) None of the above
F) All of the above

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D

Viral meningitis normally requires aggressive antiviral treatment.

A) True
B) False

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Which of the following is/are a sign or symptom of meningitis?


A) Headache
B) Stiff neck
C) White blood cells in cerebrospinal fluid
D) Fever
E) All of the choices are correct.

F) All of the above
G) B) and E)

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Encephalitis caused by arboviruses involves the development of


A) fever, headache, and rash.
B) coma, convulsions, and paralysis in severe cases.
C) myalgia and orbital pain.
D) muscle aches and joint stiffness.
E) All of the choices are correct.

F) A) and B)
G) None of the above

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Which of the following is not a prion disease?


A) Creutzfeldt-Jacob disease
B) Scrapie
C) Bovine spongiform encephalopathy
D) Subacute sclerosing panencephalitis

E) C) and D)
F) A) and B)

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The organism found in contaminated powdered infant formula that can cause meningitis is ______.


A) Escherichia coli K1
B) Escherichia coli O157:H7
C) Cronobacter sakazakii
D) Cryptococcus neoformans
E) Streptococcus agalactiae

F) D) and E)
G) A) and D)

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Subacute encephalitis may be caused by ______.


A) Toxoplasma gondii
B) prions
C) herpes simplex virus
D) persistent measles virus
E) All of the choices are correct.

F) B) and E)
G) A) and C)

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Tetanus differs from botulism in that


A) tetanus results in flaccid paralysis, while botulism paralysis is rigid.
B) tetanus results from an exotoxin, botulism from an endotoxin.
C) there is a vaccine for botulism but not for tetanus.
D) muscles cannot relax in tetanus, while muscles cannot contract in botulism.
E) All of the choices are correct.

F) C) and D)
G) B) and D)

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Subacute sclerosing panencephalitis is caused by a prion.

A) True
B) False

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Which of the following is not a causative agent of acute encephalitis?


A) JC virus
B) Toxoplasma gondii
C) Varicella-zoster virus
D) Herpes simplex virus
E) Arbovirus

F) B) and E)
G) A) and B)

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B

In both botulism and tetanus, respiratory muscles cannot facilitate breathing and, if untreated, respiratory collapse leads to death.

A) True
B) False

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The best defense against arboviruses is ______.


A) prophylactic rifampin
B) prompt treatment with acyclovir
C) vector control
D) vaccination

E) A) and B)
F) B) and D)

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The gut-brain axis refers to


A) changes in brain chemistry and behavior caused by the gut microbiota.
B) neurons in the spinal cord that connect the gut and the brain.
C) the location of dormant viruses that infect both the gut and the brain.
D) pores in the blood-brain barrier that permit the passage of glucose and other nutrients.

E) B) and C)
F) A) and C)

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A

Treatment for Neisseria meningitidis consists of ______.


A) intravenous penicillin G
B) vancomycin
C) rifampin
D) oral penicillin G
E) tetracycline

F) B) and E)
G) B) and D)

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Which of the following statements is incorrect regarding Listeria monocytogenes?


A) It is fastidious.
B) It does not produce a capsule.
C) It is resistant to salt.
D) It is resistant to cold.
E) It is resistant to heat.

F) B) and D)
G) A) and D)

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The preferred preventative measure for polio in the United States is the


A) inactive vaccine developed by Jonas Salk.
B) oral, active vaccine developed by Jonas Salk.
C) inactive vaccine developed by Albert Sabin.
D) oral, active vaccine developed by Albert Sabin.
E) No preventative measures are used because polio has been eradicated in the United States.

F) A) and E)
G) A) and B)

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In paralytic polio, which structures are damaged?


A) Brain stem
B) Diaphragm
C) Sensory nerves
D) Anterior horn cells
E) Peripheral nerves

F) C) and E)
G) B) and D)

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Which of the following diseases exhibits the highest mortality rate?


A) La Crosse encephalitis
B) Jamestown Canyon encephalitis
C) Eastern equine encephalitis
D) West Nile encephalitis

E) A) and C)
F) None of the above

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Which of the following is not true of Streptococcus pneumoniae?


A) It is a small, gram-negative coccus.
B) It is the most frequent cause of community-acquired meningitis.
C) It has a polysaccharide capsule that resists phagocytosis.
D) It produces an alpha-hemolysin and hydrogen peroxide.

E) All of the above
F) B) and C)

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Your friend was bitten by an aggressive dog with a history of biting without cause, and it is suspected to have rabies.The city health department recommends the rabies vaccination, even though she has already been exposed to the infectious agent.Which statement best describes why the vaccine can be given post-exposure?


A) There were few virus particles in the bite, so her immune system has enough time to respond.
B) Since there is no treatment available, they suggest the vaccine as a last resort.
C) The virus exhibits a long incubation period, and therefore, in many cases, this provides the vaccine adequate time to have a protective effect in the patient.
D) This particular strain of the rabies virus is probably nonpathogenic, so the vaccine is given to boost the immune system's protective functions.

E) A) and C)
F) All of the above

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