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Atopy and anaphylaxis are hypersensitivities in the category(ies)


A) type I only.
B) type I and type IV.
C) type IV only.
D) type I, type II, and type III.
E) type I, type II, type III, and type IV.

F) C) and D)
G) B) and C)

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The potential for hemolytic disease of the newborn occurs when


A) fetal Rh- cells enter an Rh+ mother.
B) fetal Rh+ cells enter an Rh+ mother.
C) maternal Rh+ cells enter an Rh- fetus.
D) fetal Rh+ cells enter an Rh- mother.
E) maternal Rh- cells enter an Rh+ fetus.

F) None of the above
G) A) and B)

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Degranulation of mast cells leads to A.decreased mucus production. B.constriction of blood vessels. C.lymph node swelling. D.constricted bronchioles.

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A. decreased mucus production....

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John, a Peace Corps worker in the country of Mali in Africa, was in a car accident while traveling through a rural area.He was treated at a tiny rural hospital, and due to his loss of blood, he required a transfusion.John has B- blood type and has never received a transfusion before.Which statement is correct regarding this scenario?


A) He can be given types O or B, no matter whether Rh- or Rh+.At this point in time, he does not have anti-Rh antibody.O has no antigens on the blood cells, so he is also safe to receive that type in addition to his own B type.
B) He can safely receive O- blood even though he makes anti-A antibodies.
C) He can be given A+ blood type in addition to B+.Rh- means that he makes no antibody to Rh.
D) The preferred blood type to give John, in addition to his own B type blood, would be AB.Both types of blood have the B antigen on the cells, so they would correspond to his own antigens.As for Rh, he can receive only Rh- blood since he would have a reaction against Rh+.

E) None of the above
F) A) and B)

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What will be the immediate action of an allergen when it enters the body for a second time?


A) Binding of allergen to adjacent IgE binding sites on mast cells and basophils
B) Histamine acts on smooth muscle
C) Prostaglandins cause vasodilation and increased vascular permeability
D) Binding of IgE by the Fc region to mast cells and basophils
E) Degranulation

F) B) and D)
G) C) and D)

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A systemic, sometimes fatal, reaction with airway obstruction and circulatory collapse is ______.


A) atopic
B) delayed
C) systemic anaphylaxis
D) antibody-mediated
E) T-cell-mediated

F) None of the above
G) B) and D)

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You were out in the garage going through boxes when you were bitten by an a spider.You tell the doctor that the spider was tiny and black, causing the doctor to think perhaps that it was a black widow spider The doctor gives you an injection of antibody to the spider venom to give you immediate protection.The antibody is produced in horses by injecting them with small doses of the spider venom, causing the horse's immune system to make large amounts of specific antibody to the antigen.The horse serum is then purified before being given to humans. A.a Staphylococcus infection related to the spider bite. B.serum sickness. C.a delayed type hypersensitivity mediated by cytotoxic T cells along with helper T cells. D.Arthus reaction. E.anaphylactic shock.

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A week later, you notice a red rash spre...

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All of the following represent potential therapy for patients with SCID except


A) stem cell grafts.
B) graft versus host.
C) transfusion with adensosine deaminase.
D) gene therapy.
E) bone marrow transplants.

F) A) and E)
G) A) and D)

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AIDS is a secondary immunodeficiency disease that affects several types of immune cells.

A) True
B) False

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Autoimmune diseases and immunodeficiencies are studied and treated by immunopathologists.

A) True
B) False

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A person with O type blood


A) lacks A and B antigens.
B) is called a universal recipient.
C) lacks all of the alleles for ABO blood type.
D) could not have the Rh factor.

E) B) and D)
F) B) and C)

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Tissue transplanted from one body site on a patient to a different body site on that patient is called a(n) ______.


A) allograft
B) xenograft
C) isograft
D) hypograft
E) autograft

F) A) and B)
G) A) and C)

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In the theory for allergic desensitization, which immunoglobulin blocks the allergen from binding with IgE?


A) IgD
B) IgE
C) IgA
D) IgM
E) IgG

F) D) and E)
G) B) and D)

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The tuberculin reaction develops within 30 minutes of the skin test in people with prior sensitization due to tuberculosis infection.

A) True
B) False

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What can be a consequence of a genetic deficiency in B-cell survival and maturity?


A) Graft versus host disease
B) Formation of autoantibodies
C) Hypogammaglobulinemia
D) Host rejection of graft

E) B) and C)
F) None of the above

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Infection with enteroviruses, such as rotavirus and cytomegalovirus, has been implicated in the onset of type I diabetes.This area of research involves the study of ______.


A) molecular mimicry
B) forbidden clones
C) the gut microbiome
D) sequestered antigens

E) B) and D)
F) A) and D)

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The study of diseases associated with excesses and deficiencies of the immune system is ______.


A) humoralpathology
B) hemopathology
C) epidemiology
D) immunopathology
E) histopathology

F) All of the above
G) A) and B)

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A person who produces anti-A and anti-B serum antibodies will have blood type ______.


A) Rh
B) A
C) AB
D) O
E) B

F) B) and D)
G) A) and B)

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What may result when grafted tissue such as bone marrow contains passenger lymphocytes?


A) Formation of autoantibodies
B) Host rejection of graft
C) Hypogammaglobulinemia
D) Graft versus host disease

E) A) and C)
F) B) and C)

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A chronic, local allergy such as hay fever is considered ______.


A) antibody-mediated
B) atopic
C) systemic anaphylactic
D) delayed
E) T-cell-mediated

F) A) and E)
G) A) and D)

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