Question 1

Acquired specific immunity involves the response of

Accepted Answer

A)  interferon.
B)  mucus membranes.
C)  skin barriers.
D)  lysozyme.
E)  B and T lymphocytes.F) A) and B)
G) C) and D)

Question 2

Activation of B cells can occur when antigen binds to B cell surface immunoglobulin receptors.

Accepted Answer

A) True 
 B)False

Question 3

Plasma cells

Accepted Answer

A)  function in allergic reactions.
B)  secrete antibodies.
C)  directly destroy target cells.
D)  activate B cells and other T cells.
E)  suppress immune reactions.F) B) and C)
G) B) and E)

Question 4

Which of the following is not true of the antigen-independent period of lymphocyte development?

Accepted Answer

A)  Many lymphocytes with different specificities are formed.
B)  Random genetic rearrangements occur to produce different surface protein receptors.
C)  Lymphocytes with specificity for self are destroyed.
D)  Lymphocytes form from stem cells in the bone marrow.
E)  Mature lymphocytes populate lymphatic organs and encounter antigens.F) A) and C)
G) None of the above

Question 5

The third line of defense against foreign invaders can be described as having _______ and ________.

Accepted Answer

A)  surveillance; complexity
B)  specificity; memory
C)  complexity, versatility
D)  diversity; barriersE) A) and B)
F) C) and D)

Question 6

An example of natural passive immunity would be

Accepted Answer

A)  giving a person immune serum globulins to chickenpox virus after exposure to the disease.
B)  chickenpox infection, followed by lifelong immunity.
C)  chickenpox vaccine triggering extended immunity to chickenpox.
D)  a fetus acquiring maternal IgG to the chickenpox virus across the placenta.E) None of the above
F) B) and C)

Question 7

Immunotherapy is the

Accepted Answer

A)  use of antitoxins.
B)  use of immune serum globulin.
C)  conferring of passive immunity.
D)  administering of preformed antibodies.
E)  All of the choices are correct.F) A) and E)
G) A) and C)

Question 8

Cell surface markers involved in immune reactions

Accepted Answer

A)  are the result of genetic expression.
B)  function in recognition of self molecules.
C)  receive and transmit chemical messages among other cells of the system.
D)  aid in cellular development.
E)  All of the choices are correct.F) All of the above
G) C) and E)

Question 9

Which process involves antibodies cross-linking cells or particles into large aggregates?

Accepted Answer

A)  Neutralization
B)  Opsonization
C)  Complement fixation
D)  Agglutination
E)  Anamnestic responseF) None of the above
G) C) and D)

Question 10

An activated TH cell produces _____, which is a growth factor for T helper cells and cytotoxic T cells.

Accepted Answer

A)  interleukin-1
B)  interleukin-2
C)  interleukin-12
D)  antiserum
E)  complementF) All of the above
G) D) and E)

Question 11

Which process involves antibodies coating microorganisms in order to facilitate phagocytosis?

Accepted Answer

A)  Opsonization
B)  Agglutination
C)  Anamnestic response
D)  Neutralization
E)  Complement fixationF) C) and E)
G) A) and D)

Question 12

During presentation of APC-bound antigen, macrophages and dendritic cells secrete the cytokine _____, which activates T helper cells.

Accepted Answer

A)  interferon
B)  histamine
C)  interleukin-2
D)  interleukin-1E) All of the above
F) B) and D)

Question 13

Which immunoglobulin class/es can fix complement?

Accepted Answer

A)  IgM only
B)  IgG only
C)  IgD only
D)  IgM and IgG
E)  IgE and IgAF) C) and D)
G) A) and B)

Question 14

All of the following statements reflect the qualities of a safe and effective vaccine, except

Accepted Answer

A)  the injected material should be antigenic, but not pathogenic.
B)  it should have a long shelf-life, be cheap to produce, and easy to administer.
C)  efficacy must be maintained by booster shots every 5 years.
D)  it should confer both humoral and cell-mediated immunity.E) None of the above
F) A) and D)

Question 15

Acellular vaccines and subunit vaccines

Accepted Answer

A)  contain modified bacterial exotoxin molecules.
B)  contain select antigenic components of a pathogen rather than whole cells or viruses.
C)  utilize DNA strands that will produce the antigen.
D)  confer passive immunity.
E)  are always genetically engineered.F) A) and C)
G) C) and D)

Question 16

Antibody molecules circulate in lymph, blood, and tissue fluids.

Accepted Answer

A) True 
 B)False

Question 17

Helper T cells

Accepted Answer

A)  activate B cells and other T cells.
B)  suppress immune reactions.
C)  function in allergic reactions.
D)  directly destroy target cells.
E)  secrete antibodies.F) A) and B)
G) B) and E)

Question 18

All nucleated cells contain

Accepted Answer

A)  class II MHC.
B)  class I MHC.
C)  secretory antibodies.
D)  IgD receptors.
E)  IgE receptors.F) B) and D)
G) A) and B)

Question 19

High titers of specific antibodies are characteristic of

Accepted Answer

A)  specific immune globulin (SIG) .
B)  gamma globulin.
C)  toxoids.
D)  immune serum globulin (ISG) .
E)  attenuated vaccines.F) C) and E)
G) A) and B)

Question 20

As an adult who never developed chickenpox infection as a child, you elect to receive the protective vaccine against this pathogen at the age of 35.This vaccine will stimulate

Accepted Answer

A)  latency.
B)  an anamnestic response.
C)  a primary immune response.
D)  a secondary immune response.E) B) and C)
F) C) and D)

Exam 15: Host Defenses II: Specific Immunity and Immunization

As an adult who never developed chickenpox infection as a child, you elect to receive the protective vaccine against this pathogen at the age of 35.This vaccine will stimulate

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During presentation of APC-bound antigen, macrophages and dendritic cells secrete the cytokine _____, which activates T helper cells.

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An example of natural passive immunity would be

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An activated TH cell produces _____, which is a growth factor for T helper cells and cytotoxic T cells.

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Helper T cells

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Which immunoglobulin class/es can fix complement?

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Plasma cells

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Which process involves antibodies cross-linking cells or particles into large aggregates?

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Acellular vaccines and subunit vaccines

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Activation of B cells can occur when antigen binds to B cell surface immunoglobulin receptors.

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The third line of defense against foreign invaders can be described as having _______ and ________.

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Antibody molecules circulate in lymph, blood, and tissue fluids.

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All nucleated cells contain

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Acquired specific immunity involves the response of

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Which process involves antibodies coating microorganisms in order to facilitate phagocytosis?

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Immunotherapy is the

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Cell surface markers involved in immune reactions

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High titers of specific antibodies are characteristic of

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Which of the following is not true of the antigen-independent period of lymphocyte development?

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All of the following statements reflect the qualities of a safe and effective vaccine, except

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An activated T_H cell produces _____, which is a growth factor for T helper cells and cytotoxic T cells.

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The third line of defense against foreign invaders can be described as having _ and __.

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