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A frameshift is caused by ______ mutations.


A) missense and insertion
B) missense and nonsense
C) nonsense and deletion
D) deletion and insertion
E) insertion and nonsense

F) A) and C)
G) A) and B)

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The _____ is all of the genetic material of a cell.


A) proteome
B) chromosome
C) genome
D) plasmid
E) prophage

F) C) and D)
G) C) and E)

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The three-base sequence on DNA that codes for an amino acid is called a/an ________.


A) codon
B) exon
C) anticodon
D) intron
E) triplet

F) B) and E)
G) A) and B)

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The operon segment composed of the gene that codes for a protein repressor is called the ________.


A) operator
B) structural locus
C) regulator
D) promoter

E) None of the above
F) B) and D)

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The RNA molecules that carry amino acids to the ribosomes during protein synthesis are called ________.


A) ribosomal RNA
B) messenger RNA
C) transfer RNA
D) primer RNA
E) ribozymes

F) All of the above
G) B) and C)

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DNA Polymerase III


A) synthesizes the primer.
B) removes the primer.
C) joins Okazaki fragments.
D) unzips the DNA helix.
E) proofreads new DNA.

F) A) and C)
G) B) and D)

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Which is incorrect about inducible operons?


A) They have genes turned off by a buildup of end product.
B) They are often for use in catabolic pathways.
C) They are normally turned off.
D) They are turned on by the substrate of the enzyme.
E) They include the lac operon.

F) C) and D)
G) C) and E)

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All of the following pertain to transcription except


A) it occurs on a ribosome in the cytoplasm.
B) it occurs before translation.
C) it requires RNA polymerase.
D) it requires a template DNA strand.
E) it is a process that contributes to the synthesis of protein.

F) C) and E)
G) None of the above

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Groups of three consecutive bases along the DNA of a gene have the code for one _______.


A) protein
B) nucleotide
C) amino acid
D) purine

E) C) and D)
F) All of the above

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DNA replication proceeds in one direction around the bacterial chromosome.

A) True
B) False

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The jumping of a gene from one location to another is done by ________.


A) conjugation
B) transposons
C) transformation
D) transduction
E) transmission

F) C) and E)
G) C) and D)

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The fields of genomics and proteomics differ in that


A) the field of genomics involves the study of DNA replication and the field of proteomics refers to the study of transcription and translation.
B) genomics refers to the study of an organism's entire genome, whereas proteomics is the study of expressed proteins.
C) genomics is the study of an organism's chromosomes and the resulting proteins are studied in the field of proteomics.
D) genomics is the study of an organism's chromosomes and proteomics is the study of transcription and translation of proteins.

E) A) and B)
F) None of the above

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The nontranscribed region of DNA to which RNA polymerase binds to initiate transcription is called the ________.


A) promoter
B) operator
C) operon
D) exon
E) intron

F) A) and E)
G) All of the above

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Which of the following is not associated with a bacterial ribosome?


A) It is a 70s holoenzyme.
B) It has a peptide (P) site.
C) It has an exit site.
D) Its small subunit provides the enzymes for making peptide bonds.
E) It has an amino acid (A) site.

F) B) and C)
G) C) and D)

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Each nucleotide is composed of


A) one phosphate, one nitrogenous base, and one sugar.
B) one phosphate, one nitrogenous base, and two sugars.
C) two phosphates, one nitrogenous base, and one sugar.
D) two phosphates, one nitrogenous base, and two sugars.
E) one phosphate, two nitrogenous bases, and one sugar.

F) C) and D)
G) A) and E)

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Lactose is a corepressor in the lac operon.

A) True
B) False

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Which of the following is incorrect about termination codons?


A) They are also called nonsense codons.
B) They are the location where the bond between the final tRNA and the polypeptide is broken.
C) They include AUG.
D) They are UAA, UAG, and UGA.
E) They do not have corresponding tRNA.

F) C) and D)
G) B) and D)

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If the wild type DNA sequence reads THE CAT ATE THE BIG RAT, what type of mutation would change the sequence to THE CAT ATE THE BAG RAT?


A) Point
B) Nonsense
C) Insertion
D) Deletion
E) Silent

F) A) and D)
G) B) and E)

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Helicase ______.


A) unwinds DNA
B) supercoils DNA
C) unwinds RNA
D) winds RNA

E) All of the above
F) B) and C)

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Which of the following additions have been made to principles of the central dogma of biology?


A) DNA information cannot be converted into RNA information.
B) Protein information can be converted into DNA information.
C) RNA can be used to regulate gene function.
D) DNA codes for proteins.

E) A) and C)
F) C) and D)

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