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Which of the following is not a characteristic of a transformed cell?


A) Viral nucleic acid integrated into host DNA
B) Decreased growth rate
C) Alterations in chromosomes
D) Changes in cell surface molecules
E) Capacity to divide indefinitely

F) C) and E)
G) A) and B)

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Viral spikes are inserted into the host cell membrane before budding or exocytosis.

A) True
B) False

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In order to synthesize proteins, a virus with a genome comprised of single-stranded negative-sense RNA


A) can directly translate its negative-sense RNA strand into proteins.
B) must use reverse transcriptase to make a negative-sense DNA strand first.
C) must use DNA polymerase to make a positive-sense DNA strand first.
D) must use its negative-sense strand as a template to make a positive-sense RNA.

E) A) and B)
F) A) and D)

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Viral growth in bird embryos can cause discrete, opaque spots in the embryonic membranes called ______.


A) patches
B) buds
C) plaques
D) cytopathic effects
E) pocks

F) A) and B)
G) A) and C)

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Successful anti-HIV drug therapies today work by blocking the action of viral reverse transcriptase.Select which step of virus multiplication that would be directly blocked by this mechanism.


A) Adsorption
B) Penetration
C) Synthesis
D) Assembly
E) Release

F) B) and D)
G) D) and E)

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You are working in a laboratory that is studying a newly isolated virus.Your job is to culture the virus using in vitro methods.Upon observing your inoculated tissue culture specimen one day, you notice clumps of cells growing on top of the original monolayer of cells.Microscopic analysis of stained cells from the culture reveal an alteration in host cell membrane protein content and chromosomal structure.Based upon this information, you hypothesize that the virus you are studying is ______.


A) a bacteriophage
B) a prion
C) a viroid
D) an oncovirus
E) a satellite virus

F) A) and D)
G) B) and C)

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A fully formed virus that can cause an infection in a host cell is called a virion.

A) True
B) False

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Host range is limited by the


A) type of nucleic acid in the virus.
B) age of the host cell.
C) type of host cell receptors on cell membrane.
D) size of the host cell.

E) B) and C)
F) A) and C)

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Viral spikes


A) are always present on enveloped viruses.
B) attach the viral capsid and envelope.
C) allow bacteria to evade host defenses.
D) are derived from host proteins.
E) are for recognition among the various types of viruses.

F) B) and E)
G) C) and D)

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Oncogenic viruses include all the following except ______.


A) hepatitis B virus
B) measles virus
C) Papillomavirus
D) HTLV-I and HTLV-II viruses
E) Epstein-Barr virus

F) A) and D)
G) All of the above

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Tamiflu is a common medication given for influenza treatment.It works by protecting and blocking sialic acid molecules on the surfaces of host cells and influenza virus envelopes as they leave the cell.Which statement reflects the mechanism of Tamiflu's action?


A) Tamiflu blocks protein synthesis of the viral genome.
B) Tamiflu interferes with the replication of +ssRNA from the -ssRNA genome of the flu virus.
C) Tamiflu interferes with the release of the budding viruses from the infected host cells.
D) Tamiflu interferes with the metabolic properties of the virus.

E) A) and C)
F) A) and D)

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Which of the following occurs during assembly?


A) The nucleocapsid is formed.
B) New viral nucleic acid is formed.
C) Viral spikes insert in host cell membrane.
D) The nucleocapsid is formed and viral spikes insert in host cell membrane.
E) The viral envelope and the host cell membrane fuse.

F) A) and D)
G) None of the above

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Viruses are the most common cause of acute infections that do not result in hospitalization.

A) True
B) False

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Helical and icosahedral are terms used to describe the shape of a viral ______.


A) spike
B) capsomere
C) envelope
D) capsid
E) core

F) B) and C)
G) B) and E)

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Viruses that infect bacteria are specifically called ______.


A) viroids
B) prions
C) bacteriophages
D) satellite viruses

E) None of the above
F) A) and D)

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Lysogeny refers to


A) altering the host range of a virus.
B) the latent state of herpes infections.
C) virions exiting host cell.
D) the viral genome inserting into bacterial host chromosome.

E) A) and B)
F) None of the above

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All of the following pertain to virus envelopes except


A) gained as a virus leaves the host cell membrane.
B) gained as a virus leaves the nuclear membrane.
C) contain special virus proteins.
D) help the virus particle attach to host cells.
E) located between the capsid and nucleic acid.

F) A) and E)
G) C) and D)

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Viral tissue specificities are called ______.


A) ranges
B) virions
C) receptacles
D) tropisms
E) uncoating

F) A) and B)
G) A) and C)

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Freshly isolated animal tissue that is placed in a growth medium and allowed to produce a cell monolayer is referred to as a/n _____ cell culture.


A) initial
B) primary
C) secondary
D) continuous
E) positive

F) B) and C)
G) A) and E)

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Which of the following is not a viral order in the classification system?


A) Caudovirales
B) Vaccinia virus
C) Nidovirales
D) Mononegavirales

E) All of the above
F) C) and D)

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