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The best defense against arboviruses is ______.


A) prophylactic rifampin
B) prompt treatment with acyclovir
C) vector control
D) vaccination

E) B) and D)
F) B) and C)

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C

As a child,you received the OPV vaccine and its boosters.Now you are going on a mission trip to Pakistan,and the vaccine is recommended by the Centers for Disease Control and Prevention.When you go to the health office for the vaccine,they give you the IPV vaccine.When you ask why you are receiving the IPV rather than the OPV,the personnel explain that


A) there is no possibility of actually developing polio from this vaccine.
B) IPV is used as a booster only, and OPV is used exclusively for children's first immunization.
C) the IPV has fewer active viruses in it than the OPV, so it is safer.
D) the IPV is preferred by patients because it can be taken orally.

E) None of the above
F) B) and C)

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Encephalitis caused by arboviruses involves the development of


A) fever, headache, and rash.
B) coma, convulsions, and paralysis in severe cases.
C) myalgia and orbital pain.
D) muscle aches and joint stiffness.
E) All of the choices are correct.

F) C) and D)
G) B) and C)

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In both botulism and tetanus,respiratory muscles cannot facilitate breathing and,if untreated,respiratory collapse leads to death.

A) True
B) False

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Cryptococcus neoformans is a ______.


A) gram-positive bacterium
B) prion
C) fungus
D) gram-negative bacterium

E) A) and B)
F) None of the above

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In rabies,spasms of muscles for swallowing lead to a fear of water.

A) True
B) False

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True

Treatment of an animal bite for possible rabies includes


A) debridement.
B) washing the bite with soap or detergent.
C) infusing the wound with human rabies immune globulin (HRIG) .
D) postexposure vaccination.
E) All of the choices are correct.

F) B) and E)
G) A) and E)

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A group of men make an annual week-long hunting trip for deer season in West Virginia.This year,they had to chase a family of squirrels out of the cabin,and during the week,they killed several deer and processed the meat,eating venison steaks most nights.All of the men had a few mosquito bites,and two cases of beer were consumed.The following week,they all developed symptoms of fever,headache,confusion,and seizures.Which of the following organisms can be ruled out as the cause of this encephalitis?


A) Jamestown Canyon Virus
B) JC Virus
C) Powassan Virus
D) Eastern Equine Encephalitis Virus

E) C) and D)
F) A) and D)

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Cerebrospinal fluid is found in the ______.


A) pia mater
B) dura mater
C) subarachnoid space
D) arachnoid mater
E) All of the choices are correct.

F) B) and E)
G) A) and B)

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C

Poliovirus initially multiplies in the ______.


A) lymphoid tissue
B) central nervous system
C) nasopharynx
D) intestine
E) basal ganglia

F) A) and E)
G) D) and E)

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Subacute sclerosing panencephalitis is caused by a prion.

A) True
B) False

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Production of a neurotoxin that prevents acetylcholine release from motor neurons at neuromuscular junctions is a characteristic of ______.


A) Clostridium botulinum
B) Clostridium tetani
C) Clostridium difficile
D) Clostridium perfringens

E) None of the above
F) A) and B)

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Which organism is a common cause of meningitis in AIDS patients and can be found in bird droppings?


A) Listeria monocytogenes
B) Neisseria meningitidis
C) Cryptococcus neoformans
D) Streptococcus agalactiae
E) Haemophilus influenzae

F) A) and B)
G) D) and E)

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The preferred preventative measure for polio in the United States is the


A) inactive vaccine developed by Jonas Salk.
B) oral, active vaccine developed by Jonas Salk.
C) inactive vaccine developed by Albert Sabin.
D) oral, active vaccine developed by Albert Sabin.
E) No preventative measures are used because polio has been eradicated in the United States.

F) B) and E)
G) C) and E)

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The gut-brain axis refers to


A) changes in brain chemistry and behavior caused by the gut microbiota.
B) neurons in the spinal cord that connect the gut and the brain.
C) the location of dormant viruses that infect both the gut and the brain.
D) pores in the blood-brain barrier that permit the passage of glucose and other nutrients.

E) B) and C)
F) All of the above

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Which of the following is caused by Haemophilus influenzae?


A) Pharyngitis
B) Tetanus
C) Kuru
D) Influenza (flu)
E) Bacterial meningitis

F) All of the above
G) A) and D)

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Which of the following is not a prion disease?


A) Creutzfeldt-Jacob disease
B) Scrapie
C) Bovine spongiform encephalopathy
D) Subacute sclerosing panencephalitis

E) A) and D)
F) A) and C)

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Infectious diseases of the nervous system include those that affect the meninges only (meningitis) ,those that affect both the meninges and the brain (meningoencephalitis) ,and those that affect the brain only (encephalitis) .From the list below,identify the disease and its classification that is mismatched.


A) African sleeping sickness; encephalitis
B) La Crosse Virus infection; encephalitis
C) Naegleria fowleri infection; meningoencephalitis
D) polio; meningitis
E) Valley Fever; meningitis

F) B) and E)
G) D) and E)

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Patients with Creutzfeldt-Jacob disease live ______ post diagnosis.


A) less than 1 year
B) 1 to 5 years
C) 5 to 10 years
D) 10 to 20 years
E) greater than 25 years

F) C) and E)
G) A) and E)

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Arthrospores of Coccidioides immitis develop into ______ that will release endospores into the lungs.


A) capsules
B) hyphae
C) capsids
D) spherules
E) buds

F) None of the above
G) B) and C)

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