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You do not really want to get your 3 children vaccinated. Your view is why do it when others around you will get the vaccine and end up protecting you and your children. Which is an accurate statement that your physician may provide to you in response to your challenge to vaccination?


A) This is not a smart choice. If enough people choose not to get vaccinated, the susceptible population grows to a large size, breaking the protective effect of herd immunity.
B) Your choice is fine; your children will never become infected since this is actually the basis of herd immunity.
C) This is not a smart choice. You could face potential arrest for not vaccinating your child per the regulations of the U.S. government.
D) Your choice is fine; maybe you will change your mind when your child goes to college

E) A) and B)
F) B) and C)

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Which of the following do not serve as antigen presenting cells?


A) Dendritic cells
B) Basophils
C) Macrophages
D) B lymphocytes

E) None of the above
F) B) and D)

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Cytotoxic T cells


A) secrete interleukin-2 to stimulate B and T cells.
B) lack specificity for antigen.
C) secrete granzymes and perforins that damage target cells.
D) are activated by free, soluble antigens.

E) B) and D)
F) All of the above

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Which of the following is not true of the antigen-independent period of lymphocyte development?


A) Many lymphocytes with different specificities are formed.
B) Random genetic rearrangements occur to produce different surface protein receptors.
C) Lymphocytes with specificity for self are destroyed.
D) Lymphocytes form from stem cells in the bone marrow.
E) Mature lymphocytes populate lymphatic organs and encounter antigens.

F) None of the above
G) A) and E)

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What type of cells secrete antibodies?


A) Antigen-presenting cells
B) Cytotoxic T cells
C) Helper T cells
D) Plasma cells
E) Memory B cells

F) A) and B)
G) C) and E)

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Immunotherapy is the


A) use of antitoxins.
B) use of immune serum globulin.
C) conferring of passive immunity.
D) administering of preformed antibodies.
E) All of the choices are correct.

F) A) and B)
G) A) and C)

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Gamma globulin can be given as immunotherapy to confer artificial passive immunity.

A) True
B) False

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The most significant cells in graft rejection are


A) delayed hypersensitivity T cells.
B) natural killer (NK) cells.
C) suppressor T cells.
D) cytotoxic T cells.
E) helper T cells.

F) B) and E)
G) None of the above

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Specific immunity provides long-lasting protection through the production of _____.


A) memory cells
B) plasma cells
C) T helper cells
D) antibodies
E) phagocytotic cells

F) D) and E)
G) C) and D)

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Lymphocytes


A) possess MHC antigens for recognizing self.
B) have membrane receptors that recognize foreign antigens.
C) gain tolerance to self by destruction of lymphocytes that could react against self.
D) develop into clones of B and T cells with extreme variations of specificity.
E) All of the choices are correct.

F) C) and D)
G) A) and D)

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The molecular fragment on an antigen molecule that a lymphocyte recognizes and responds to is called a(n) ______.


A) hapten
B) antigen binding site
C) variable region
D) epitope

E) B) and C)
F) All of the above

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Live,attenuated vaccines


A) include the Sabin polio vaccine.
B) include the measles, mumps, rubella vaccine (MMR) .
C) contain viable microbes that can multiply in the person.
D) require smaller doses and fewer boosters compared to inactivated vaccines.
E) All of the choices are correct.

F) B) and D)
G) C) and E)

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Destruction of lymphocytes with self-specificity is called ______.


A) proliferation.
B) differentiation.
C) clonal selection.
D) clonal deletion.
E) hypersensitivity.

F) A) and D)
G) A) and C)

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