Question 1

Distances on a genetic map are measured in _____ units.

Accepted Answer

A)  centromere
B)  DNA
C)  dalton
D)  centimorganE) B) and C)
F) A) and C)

Question 2

Linkage disequilibrium is

Accepted Answer

A)  the tendency of genes to be totally randomized during meiosis.
B)  the tendency of genes not to be randomized during meiosis.
C)  the tendency of genes of single nucleotides polymorphisms to be rearranged during meiosis because of crossing over.
D)  the tendency of genes to link together within certain blocks along the chromosome.
E)  the tendency of contigs being so randomized that mapping becomes an issue for gene sequencing.F) C) and D)
G) None of the above

Question 3

Groups of related,but distinctly different,genes that appear to have arisen from a single ancestral gene are referred to as

Accepted Answer

A)  segmental duplications.
B)  pseudogenes.
C)  tandem clusters.
D)  multigene families.
E)  expressed sequences.F) A) and C)
G) A) and D)

Question 4

Your research project involves the characterization of a novel protein.To learn more about its function you perform a yeast two-hybrid screen to identify potential interacting proteins.In your first screening attempt,you isolate one clone.You send the clone to be sequenced at the local sequencing facility.After translating the sequencing data,what should you do to (i) find out what type of protein this clone encodes,and (ii) get an idea about its possible function?

Accepted Answer

A)  Run a blast search.
B)  Identify the intron/exon organization.
C)  Localize the gene to a specific chromosomal region.
D)  Search the human genome sequence for your clone.E) B) and C)
F) B) and D)

Question 5

Which of the following techniques can be used to detect chromosomal abnormalities?

Accepted Answer

A)  EST
B)  FISH
C)  STS
D)  SNPE) A) and C)
F) All of the above

Question 6

The sequencing method that cuts DNA segments into fragments,arranges those fragments based on overlapping nucleotide sequences,and then clones these fragments is called

Accepted Answer

A)  shotgun sequencing.
B)  clone by clone sequencing.
C)  RFLP sequencing.
D)  consensus sequencing.E) None of the above
F) A) and D) B

Question 7

Chloroplasts can replicate independently because

Accepted Answer

A)  of synteny.
B)  it has its own genome.
C)  of its repetitive DNA sequences.
D)  of its ability to use restriction enzymes.
E)  it has several contigs.F) D) and E)
G) A) and E)

Question 8

The majority (45%) of the human genome is composed of

Accepted Answer

A)  introns.
B)  exons.
C)  templates.
D)  transposons.
E)  pseudogenes.F) A) and E)
G) C) and E) D

Question 9

______ maps show the relative location of genes on a chromosome as determined by recombination frequencies.

Accepted Answer

A)  DNA
B)  Genetic
C)  Chromosomal
D)  PhysicalE) B) and C)
F) A) and D)

Question 10

How is the study of genomics expected to influence future health care?

Accepted Answer

A)  The study of genomics is expected to provide insight into the relationship between genes and the environment,and why certain people get sick while others remain healthy.It should enable us to learn more about the causes and effects of various diseases,illnesses,and infections.Such information will help us to identify ways to improve health care and prevent disease.
B)  The study of genomics will allow us to treat,with the use of genetic engineering,various diseases of genetic origin.It is just a matter of time before we are able to treat all diseases of genetic origin with this technique.
C)  The study of genomics will allow us to use bacteria and viruses to create vaccinations for virually all diseases of genetic origin.D) All of the above
E) A) and B)

Question 11

Microarrays are created by

Accepted Answer

A)  robotically placing DNA on to a microscope slide and probing with RNA from the tissue of interest.
B)  robotically placing DNA on to a microscope slide and probing with another DNA from the tissue of interest.
C)  robotically placing DNA on to a microscope slide and probing with SNPs from the tissue of interest.
D)  robotically placing DNA on to a microscope slide and probing with STSs from the tissue of interest.
E)  clone by clone sequencing.F) B) and D)
G) A) and B)

Question 12

A genome sequence with minimal gaps,with the sequences in the correct order,and having no more that 1% error in 10,000 nucleotides would be considered a

Accepted Answer

A)  PCR sequence.
B)  draft sequence.
C)  finished sequence.
D)  shotgun sequence.
E)  clone by clone sequencE.F) A) and B)
G) C) and E)

Question 13

A human gene is composed of numerous fragments of protein-encoding information known as ______.

Accepted Answer

A)  DNA
B)  mRNA
C)  exons
D)  intronsE) None of the above
F) A) and B)

Question 14

Long interspersed elements (LINES) are a type of

Accepted Answer

A)  pseudogene.
B)  proteone.
C)  exon.
D)  intron.
E)  transposon.F) C) and D)
G) B) and E)

Question 15

Which of the following organisms has the largest genome?

Accepted Answer

A)  rice
B)  human
C)  fruit fly
D)  yeastE) C) and D)
F) A) and B)

Question 16

______ maps are generated using actual landmarks within DNA sequences.

Accepted Answer

A)  Genetic
B)  DNA
C)  Physical
D)  ChromosomalE) A) and D)
F) B) and D)

Question 17

The sequencing method that cuts the DNA of an entire chromosome into small fragments and then clones these fragments is called

Accepted Answer

A)  shotgun sequencing.
B)  clone by clone sequencing.
C)  RFLP sequencing.
D)  consensus sequencing.E) None of the above
F) A) and D)

Question 18

The majority of DNA in a human is

Accepted Answer

A)  composed of short interspersed elements.
B)  non-coding.
C)  simple sequence repeats.
D)  segmental duplications.
E)  structural.F) B) and C)
G) A) and E)

Question 19

Rice and its grain relatives,maize,barley,and wheat,diverged from a common ancestor 50 million years ago,however the chromosomes of these plants demonstrate extensive conserved arrangements of segments.This phenomenon is called

Accepted Answer

A)  a linkage disequilibrium.
B)  a single nucleotide polymorphisms.
C)  a contig.
D)  synteny.
E)  expressed sequence equilibrium.F) B) and D)
G) D) and E) D

Question 20

A _____ consists of all of the DNA in a nucleus of a cell.

Accepted Answer

A)  genome
B)  chromosome
C)  gene
D)  proteinE) C) and D)
F) B) and D)

Exam 18: Genomics

Distances on a genetic map are measured in _____ units.

Correct Answer
verified

Linkage disequilibrium is

Correct Answer
verified

Groups of related,but distinctly different,genes that appear to have arisen from a single ancestral gene are referred to as

Correct Answer
verified

Correct Answer
verified

Which of the following techniques can be used to detect chromosomal abnormalities?

Correct Answer
verified

The sequencing method that cuts DNA segments into fragments,arranges those fragments based on overlapping nucleotide sequences,and then clones these fragments is called

Correct Answer
verified
B

Chloroplasts can replicate independently because

Correct Answer
verified

The majority (45%) of the human genome is composed of

Correct Answer
verified
D

______ maps show the relative location of genes on a chromosome as determined by recombination frequencies.

Correct Answer
verified

How is the study of genomics expected to influence future health care?

Correct Answer
verified

Microarrays are created by

Correct Answer
verified

A genome sequence with minimal gaps,with the sequences in the correct order,and having no more that 1% error in 10,000 nucleotides would be considered a

Correct Answer
verified

A human gene is composed of numerous fragments of protein-encoding information known as ______.

Correct Answer
verified

Long interspersed elements (LINES) are a type of

Correct Answer
verified

Which of the following organisms has the largest genome?

Correct Answer
verified

______ maps are generated using actual landmarks within DNA sequences.

Correct Answer
verified

The sequencing method that cuts the DNA of an entire chromosome into small fragments and then clones these fragments is called

Correct Answer
verified

The majority of DNA in a human is

Correct Answer
verified

Rice and its grain relatives,maize,barley,and wheat,diverged from a common ancestor 50 million years ago,however the chromosomes of these plants demonstrate extensive conserved arrangements of segments.This phenomenon is called

Correct Answer
verified
D

A _____ consists of all of the DNA in a nucleus of a cell.

Correct Answer
verified

Exam 18: Genomics

Distances on a genetic map are measured in _____ units.

Correct AnswerverifiedShow Answer

Linkage disequilibrium is

Correct AnswerverifiedShow Answer

Groups of related,but distinctly different,genes that appear to have arisen from a single ancestral gene are referred to as

Correct AnswerverifiedShow Answer

Correct AnswerverifiedShow Answer

Which of the following techniques can be used to detect chromosomal abnormalities?

Correct AnswerverifiedShow Answer

The sequencing method that cuts DNA segments into fragments,arranges those fragments based on overlapping nucleotide sequences,and then clones these fragments is called

Correct AnswerverifiedB

Chloroplasts can replicate independently because

Correct AnswerverifiedShow Answer

The majority (45%) of the human genome is composed of

Correct AnswerverifiedD

______ maps show the relative location of genes on a chromosome as determined by recombination frequencies.

Correct AnswerverifiedShow Answer

How is the study of genomics expected to influence future health care?

Correct AnswerverifiedShow Answer

Microarrays are created by

Correct AnswerverifiedShow Answer

A genome sequence with minimal gaps,with the sequences in the correct order,and having no more that 1% error in 10,000 nucleotides would be considered a

Correct AnswerverifiedShow Answer

A human gene is composed of numerous fragments of protein-encoding information known as ______.

Correct AnswerverifiedShow Answer

Long interspersed elements (LINES) are a type of

Correct AnswerverifiedShow Answer

Which of the following organisms has the largest genome?

Correct AnswerverifiedShow Answer

______ maps are generated using actual landmarks within DNA sequences.

Correct AnswerverifiedShow Answer

The sequencing method that cuts the DNA of an entire chromosome into small fragments and then clones these fragments is called

Correct AnswerverifiedShow Answer

The majority of DNA in a human is

Correct AnswerverifiedShow Answer

Rice and its grain relatives,maize,barley,and wheat,diverged from a common ancestor 50 million years ago,however the chromosomes of these plants demonstrate extensive conserved arrangements of segments.This phenomenon is called

Correct AnswerverifiedD

A _____ consists of all of the DNA in a nucleus of a cell.

Correct AnswerverifiedShow Answer

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B

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D

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D

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