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Which is mismatched?


A) food allergy - type I hypersensitivity
B) poison ivy dermatitis - type IV hypersensitivity
C) serum sickness - type III hypersensitivity
D) transfusion reaction - type II hypersensitivity
E) hay fever - type IV hypersensitivity

F) None of the above
G) C) and E)

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AIDS is a secondary immunodeficiency disease that affects several types of immune cells.

A) True
B) False

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A female who is Rh-


A) inherited two dominant genes.
B) is in the majority of the population with regard to Rh status.
C) is at risk for a pregnancy resulting in hemolytic disease of the newborn.
D) can never have an Rh+ baby.

E) C) and D)
F) A) and B)

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In the situation of systemic lupus erythematosis (called lupus) ,complexes of antibody and antigen form and these immune complexes insert themselves into small blood vessels,joints,heart,and kidney,causing damage to the organ tissue.The course of the disease is unpredictable,with periods of illness alternating with remissions.How is lupus,a type III hypersensitivity,similar to infectious allergy,a type IV hypersensitivity reaction?


A) The mechanism of both lupus and infectious allergy involve large amounts of inflammatory chemicals released into tissue.
B) Both lupus and infectious allergy involve large amounts of antibody production.
C) Both lupus and infectious allergy are immediate-type hypersensitivities,occurring within a few hours.
D) Both lupus and infectious allergy have IgE in their mechanisms.

E) All of the above
F) A) and D)

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In multiple sclerosis,autoantibodies attack


A) myelin sheath cells of the nervous system.
B) acetylcholine receptors on smooth muscle.
C) acetylcholine receptors on skeletal muscle.
D) sodium pump proteins in the cell membrane.
E) cells in thyroid follicles.

F) A) and E)
G) A) and D)

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Histamine causes all of the following except


A) increased sensitivity to pain.
B) constriction of smooth muscle of bronchi and the intestine.
C) relaxation of vascular smooth muscle.
D) wheal and flare reaction in skin.
E) pruritis and headache.

F) B) and D)
G) C) and D)

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Food allergies include gastrointestinal symptoms and often hives.

A) True
B) False

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Autoantibodies cause tissue injury in all of the following diseases except


A) rheumatoid arthritis.
B) myasthenia gravis.
C) Graves' disease.
D) tuberculin reaction.
E) multiple sclerosis.

F) A) and D)
G) A) and C)

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A systemic,sometimes fatal,reaction with airway obstruction and circulatory collapse is


A) delayed.
B) T-cell-mediated.
C) atopic.
D) antibody-mediated.
E) systemic anaphylaxis.

F) B) and D)
G) D) and E)

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Bee sting venom is considered to be which type of allergen?


A) ingestant
B) inhalant
C) injectant
D) contactant

E) A) and B)
F) A) and C)

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Autoimmunity is typically due to


A) transfusion reaction.
B) IgE and mast cells.
C) autoantibodies and T cells.
D) graft rejection.
E) a deficiency in T-cell development.

F) B) and D)
G) B) and C)

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Large quantities of antibodies that react to the second entry of antigen and lead to formation of antigen-antibody complexes occurs in


A) serum sickness.
B) delayed hypersensitivity.
C) anaphylaxis.
D) hemolytic disease of the newborn.

E) A) and D)
F) B) and C)

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Once a mother has been sensitized to the Rh factor,


A) all other Rh+ fetuses are at risk.
B) she can be given RhoGAM in future pregnancies to prevent hemolytic disease of the newborn.
C) she can never again have a low risk pregnancy.
D) only future Rh- fetuses are at risk.
E) None of the choices is correct.

F) B) and E)
G) A) and C)

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Eczema is an autoimmune disorder.

A) True
B) False

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A viral infection can lead to the development of type I diabetes.

A) True
B) False

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Transfusion of the wrong blood type can cause


A) recipient antibody activation of the complement cascade to attack the RBCs.
B) fever and anemia.
C) systemic shock and kidney failure.
D) massive hemolysis of the donor RBCs.
E) All of the choices are correct.

F) None of the above
G) C) and E)

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All of the following are involved in type II hypersensitivity except


A) IgM.
B) IgG.
C) IgE.
D) complement.
E) foreign cells.

F) All of the above
G) A) and D)

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The major categories of hypersensitivities that typically involve a B-cell immunoglobulin response include


A) type I only.
B) type I and type IV.
C) type IV only.
D) type I,type II,and type III.
E) type I,type II,type III,and type IV.

F) C) and D)
G) A) and D)

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During graft rejection,cytotoxic T cells of the recipient recognize and respond to foreign class I MHC receptors on the grafted cells.

A) True
B) False

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Systemic anaphylaxis can quickly result in airway blockage,shock,and death.

A) True
B) False

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