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All of the following are associated with IgE and mast-cell-mediated allergy except


A) drug allergy.
B) eczema.
C) anaphylaxis.
D) allergic asthma.
E) systemic lupus erythematosus.

F) A) and E)
G) A) and C)

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The study of diseases associated with excesses and deficiencies of the immune system is


A) humoralpathology.
B) hemopathology.
C) epidemiology.
D) immunopathology.
E) histopathology.

F) C) and E)
G) D) and E)

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Corticosteroids will


A) inhibit the activity of lymphocytes.
B) bind to histamine receptors on target organs.
C) block synthesis of leukotrienes.
D) relieve inflammatory symptoms.
E) reverse spasms of respiratory smooth muscles.

F) D) and E)
G) A) and D)

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Allergies run in families because


A) immunoglobulins pass from mother to fetus.
B) immunoglobulins pass through breast milk.
C) the variable region of antibodies is genetically determined.
D) the relative production of IgE is inherited.

E) A) and B)
F) A) and C)

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What can be a consequence of a genetic deficiency in B-cell survival and maturity?


A) host rejection of graft
B) graft versus host disease
C) formation of autoantibodies
D) hypogammaglobulinemia

E) C) and D)
F) None of the above

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The tuberculin reaction develops within 30 minutes of the skin test in people with prior sensitization due to tuberculosis infection.

A) True
B) False

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Which of the following is not a target for immune complex deposition?


A) blood vessels and skin
B) heart and lungs
C) brain
D) joints
E) kidneys

F) A) and E)
G) C) and D)

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Human blood types involve all of the following except


A) MHC genes.
B) ABO antigen markers.
C) inheritance of two of three possible alleles.
D) genetically determined glycoprotein markers.
E) genes that code for an enzyme that adds a terminal carbohydrate to RBC receptors.

F) B) and C)
G) A) and E)

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Degranulation of mast cells leads to


A) airway obstruction.
B) headache.
C) dilated blood vessels.
D) constricted bronchioles.

E) All of the above
F) C) and D)

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The chemical mediator that causes prolonged bronchospasm,vascular permeability,and mucus secretion of asthmatic patients is


A) prostaglandin.
B) histamine.
C) leukotriene.
D) serotonin.
E) platelet-activating factor.

F) A) and E)
G) A) and B)

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Which type/s of hypersensitivities is IgG is involved with?


A) anaphylaxis
B) antibody-mediated
C) immune complex-mediated
D) Both anaphylaxis and antibody-mediated.
E) Both antibody-mediated and immune complex-mediated.

F) A) and B)
G) B) and E)

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You were out in the garage going through boxes when you were bitten by an a spider.You tell the doctor that the spider was tiny and black,causing the doctor to think perhaps that it was a black widow spider The doctor gives you an injection of antibody to the spider venom to give you immediate protection.The antibody is produced in horses by injecting them with small doses of the spider venom,causing the horse's immune system to make large amounts of specific antibody to the antigen.The horse serum is then purified before being given to humans. A week later,you notice a red rash spreading away from the injection spot,where the doctor gave you the anti-venom shot.A few days later,the rash has spread and swelling in also present.You have joint pain as well as sore muscles all over your body.The lymph nodes in the armpit are swollen and painful.Going back to the doctor,he diagnoses you with:


A) a Staphylococcus infection related to the spider bite.
B) anaphylactic shock.
C) a delayed type hypersensitivity mediated by cytotoxic T cells along with helper T cells.
D) serum sickness.
E) Arthus reaction.

F) A) and E)
G) B) and E)

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