Question 1

What antibiotic is mixed with neomycin and polymyxin to make an antibiotic ointment (Neosporin) for superficial skin infections?

Accepted Answer

A)  vancomycin
B)  bacitracin
C)  chloramphenicol
D)  streptomycin
E)  clindamycinF) None of the above
G) C) and D)

Question 2

Antimicrobial drugs that inhibit folic acid synthesis work with no side effects because mammals must get folic acid from their diet.

Accepted Answer

A) True 
 B)False

Question 3

The MIC is the smallest concentration of an antimicrobial required to inhibit the growth of the microbe.

Accepted Answer

A) True 
 B)False

Question 4

Drug susceptibility testing determines

Accepted Answer

A)  the patient's response to various antimicrobials.
B)  the pathogen's response to various antimicrobials.
C)  if normal biota will be affected by antimicrobials.
D)  if the drug is increasing to toxic levels in a patient.E) A) and B)
F) C) and D)

Question 5

All of the following pertain to fluoroquinolones except

Accepted Answer

A)  broad spectrum.
B)  include ciprofloxacin and levofloxacin.
C)  are nephrotoxic.
D)  used to treat respiratory,urinary,and sexually transmitted infections.
E)  readily absorbed from intestines.F) None of the above
G) B) and E)

Question 6

Each of the following is a mechanism for drug resistance transfer between microorganisms except

Accepted Answer

A)  transposons.
B)  R-plasmids.
C)  conjugation.
D)  mutation.E) A) and B)
F) All of the above D

Question 7

The use of antibiotics in cattle feed leads to the development of antibiotic-resistant bacteria.

Accepted Answer

A) True 
 B)False

Question 8

Which antibiotic is used to treat MRSA and VRE infections?

Accepted Answer

A)  synercid
B)  clindamycin
C)  linezolid
D)  azithromycin
E)  clarithromycinF) A) and B)
G) A) and C)

Question 9

Species of Bacillus produce bacitracin and the polymyxin drugs.

Accepted Answer

A) True 
 B)False  True

Question 10

All _____ consist of a thiazolidine ring,a beta-lactam ring,and an R group.

Accepted Answer

A)  penicillins
B)  tetracyclines
C)  macrolides
D)  cephalosporins
E)  aminoglycosidesF) A) and B)
G) All of the above

Question 11

You have given a dosage of an antibiotic to a patient for his infection,but the patient is not getting any better.The MIC tests shows that the drug that you prescribed,at the dosage that was given,should work against this particular strain of bacterium.What do you think might be the problem?

Accepted Answer

A)  The drug might be broken down in the patient's body before it can have its full effect on the bacterium.
B)  The patient is resistant to the drug.
C)  The bacterium is immune to the chemical effects of the drug.
D)  The drug was improperly made at the pharmaceutical company,so is no longer effective.E) B) and D)
F) A) and C)

Question 12

A chemical that inhibits beta-lactamase enzymes is

Accepted Answer

A)  synercid.
B)  penicillinase.
C)  aztreonam.
D)  clavulanic acid.
E)  imipenem.F) A) and E)
G) A) and D)

Question 13

Which of the following is not a drug group used to treat fungal infections?

Accepted Answer

A)  quinolones
B)  macrolide polyene antibiotics
C)  griseofulvin
D)  synthetic azoles
E)  flucytosineF) A) and C)
G) B) and D)

Question 14

The use of vaginal inserts of Lactobacillus to restore a healthy acidic environment is an example of

Accepted Answer

A)  prebiotics.
B)  probiotics.
C)  lantibiotics.
D)  phytobiotics.
E)  riboswitches.F) C) and D)
G) C) and E) B

Question 15

Resistance genes can be transferred to other bacterial cells during transformation,transduction,and conjugation.

Accepted Answer

A) True 
 B)False

Question 16

Antiviral drugs that target reverse transcriptase would be used to treat infections caused by:

Accepted Answer

A)  influenza A virus.
B)  HIV.
C)  herpes zoster virus.
D)  respiratory syncytial virus.
E)  hepatitis C virus.F) A) and D)
G) C) and D)

Question 17

Ampicillin,amoxicillin,mezlocillin,and penicillin G all have

Accepted Answer

A)  a beta-lactam ring.
B)  resistance to the action of penicillinase.
C)  a semisynthetic nature.
D)  an expanded spectrum of activity.E) All of the above
F) None of the above

Question 18

Which of the following is not a therapeutic benefit of interferon?

Accepted Answer

A)  reduces healing time
B)  increases white blood cell count
C)  prevents or reduces some cold symptoms
D)  slows progress of some cancers
E)  treats hepatitis CF) A) and B)
G) A) and E)

Question 19

Penicillins and cephalosporins

Accepted Answer

A)  interfere with elongation of peptidoglycan.
B)  are metabolic analogs of PABA and block folic acid synthesis.
C)  attach to the 30S ribosomal subunit and disrupt protein synthesis.
D)  damage cell membranes.
E)  block peptidases that cross-link glycan molecules.F) A) and E)
G) All of the above

Question 20

Antibiotics are derived from all of the following except

Accepted Answer

A)  Penicillium.
B)  Bacillus.
C)  Staphylococcus.
D)  Streptomyces.
E)  Cephalosporium.F) A) and B)
G) B) and D)

Exam 12: Drugs, Microbes, host-The Elements of Chemotherapy

What antibiotic is mixed with neomycin and polymyxin to make an antibiotic ointment (Neosporin) for superficial skin infections?

Correct AnswerverifiedShow Answer

Antimicrobial drugs that inhibit folic acid synthesis work with no side effects because mammals must get folic acid from their diet.

Correct AnswerverifiedShow Answer

The MIC is the smallest concentration of an antimicrobial required to inhibit the growth of the microbe.

Correct AnswerverifiedShow Answer

Drug susceptibility testing determines

Correct AnswerverifiedShow Answer

All of the following pertain to fluoroquinolones except

Correct AnswerverifiedShow Answer

Each of the following is a mechanism for drug resistance transfer between microorganisms except

Correct AnswerverifiedD

The use of antibiotics in cattle feed leads to the development of antibiotic-resistant bacteria.

Correct AnswerverifiedShow Answer

Which antibiotic is used to treat MRSA and VRE infections?

Correct AnswerverifiedShow Answer

Species of Bacillus produce bacitracin and the polymyxin drugs.

Correct AnswerverifiedTrue

All _____ consist of a thiazolidine ring,a beta-lactam ring,and an R group.

Correct AnswerverifiedShow Answer

You have given a dosage of an antibiotic to a patient for his infection,but the patient is not getting any better.The MIC tests shows that the drug that you prescribed,at the dosage that was given,should work against this particular strain of bacterium.What do you think might be the problem?

Correct AnswerverifiedShow Answer

A chemical that inhibits beta-lactamase enzymes is

Correct AnswerverifiedShow Answer

Which of the following is not a drug group used to treat fungal infections?

Correct AnswerverifiedShow Answer

The use of vaginal inserts of Lactobacillus to restore a healthy acidic environment is an example of

Correct AnswerverifiedB

Resistance genes can be transferred to other bacterial cells during transformation,transduction,and conjugation.

Correct AnswerverifiedShow Answer

Antiviral drugs that target reverse transcriptase would be used to treat infections caused by:

Correct AnswerverifiedShow Answer

Ampicillin,amoxicillin,mezlocillin,and penicillin G all have

Correct AnswerverifiedShow Answer

Which of the following is not a therapeutic benefit of interferon?

Correct AnswerverifiedShow Answer

Penicillins and cephalosporins

Correct AnswerverifiedShow Answer

Antibiotics are derived from all of the following except

Correct AnswerverifiedShow Answer

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D

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True

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B

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