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Successful anti-HIV drug therapies today work by blocking the action of viral reverse transcriptase.Select which step of virus multiplication that would be directly blocked by this mechanism:


A) adsorption
B) penetration
C) synthesis
D) assembly
E) release

F) A) and B)
G) C) and D)

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C

Host range is limited by


A) type of nucleic acid in the virus.
B) age of the host cell.
C) type of host cell receptors on cell membrane.
D) size of the host cell.

E) A) and C)
F) C) and D)

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The event that occurs in bacteriophage multiplication that does not occur in animal virus replication is


A) adsorption to the host cells.
B) injection of only the viral nucleic acid into the host cell.
C) host cell synthesis of viral enzymes and capsid proteins.
D) assembly of nucleocapsids.
E) replication of viral nucleic acid.

F) C) and D)
G) A) and B)

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Viral spikes are inserted into the host cell membrane before budding or exocytosis.

A) True
B) False

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The correct sequence of events in viral multiplication is:


A) penetration,uncoating,synthesis,adsorption,assembly,release
B) uncoating,penetration,synthesis,assembly,absorption,release
C) adsorption,penetration,uncoating,synthesis,assembly,release
D) assembly,synthesis,uncoating,release,penetration,adsorption
E) adsorption,release,synthesis,uncoating,assembly,penetration

F) A) and E)
G) None of the above

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Viral nucleic acid types include:


A) double-stranded DNA
B) single-stranded DNA
C) double-stranded RNA
D) single-stranded RNA
E) All of the choices are correct.

F) B) and D)
G) C) and E)

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Some animals can become infected with multiple influenza virus strains usually associated with other animals.Which statement below describes the result of these infections?


A) A new novel strain of flu may be produced,for which the human population has no immunity.
B) Major genetic variations in the flu viruses can be reproduced.
C) The viral genomes within the host cells can become recombined.
D) All of the above are possible outcomes.

E) C) and D)
F) A) and C)

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A common method for cultivating viruses in the lab is to use in vitro systems called _____ cultures.


A) embryo
B) cell
C) plaque
D) bacteriophage
E) egg

F) C) and D)
G) B) and E)

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The core of every virus particle always contains


A) DNA.
B) capsomeres.
C) enzymes.
D) DNA and RNA.
E) either DNA or RNA.

F) A) and B)
G) A) and C)

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Mammalian viruses capable of starting tumors are


A) chronic latent viruses.
B) oncoviruses.
C) syncytia.
D) inclusion bodies.
E) cytopathic.

F) A) and B)
G) A) and C)

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B

Viruses are used to produce vaccines for prevention of certain viral infections.

A) True
B) False

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Viruses with _____-sense RNA contain the correct message for translation,while viruses with _____-sense RNA must first be converted into a correct message.


A) positive;negative
B) negative;positive
C) primary;secondary
D) secondary;primary
E) intermediate;primary

F) D) and E)
G) A) and C)

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Which of the following is incorrect about prophages?


A) present when the virus is in lysogeny
B) formed when viral DNA enters the bacterial chromosome
C) replicated with host DNA and passed on to progeny
D) cause lysis of host cells
E) occur when temperate phages enter host cells

F) A) and E)
G) A) and C)

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Which of the following is not associated with every virus?


A) envelope
B) capsomeres
C) capsid
D) nucleic acid
E) genome

F) None of the above
G) A) and B)

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Select the statement that most accurately describes the action of antimicrobial drugs today.


A) Antiviral drug treatment is more effective than vaccination against a viral disease.
B) Effective antiviral drugs have a long history of development and use.
C) Antiviral drugs often result in toxic side effects due to their inhibition of host cell activity.
D) The development of antiviral drug resistance has not been observed,as compared to the high rate of antibiotic resistance seen today.

E) None of the above
F) B) and C)

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Two noncellular agents,smaller than viruses,are infectious proteins called _____ and infectious RNA strands called _____.


A) prions;capsomeres
B) virions;prions
C) viroids;phages
D) prions;phages
E) prions;viroids

F) A) and B)
G) None of the above

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Viruses acquire envelopes around their nucleocapsids during


A) replication.
B) assembly.
C) adsorption.
D) release.
E) penetration.

F) D) and E)
G) B) and E)

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Viruses are not filterable.

A) True
B) False

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Viral growth in bird embryos can cause discrete,opaque spots in the embryonic membranes called


A) patches.
B) buds.
C) plaques.
D) cytopathic effects.
E) pocks.

F) C) and D)
G) B) and D)

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E

Which of the following is not a typical capsid shape?


A) tetrahedral
B) complex
C) helical
D) icosahedron
E) viroid.

F) B) and C)
G) D) and E)

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