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Figuer: This diagram shows the steps in mitosis, with labels to reference in the questions below. Figuer: This diagram shows the steps in mitosis, with labels to reference in the questions below.   -The phase of mitosis in which the chromosomes condense and centrosomes move to opposite poles of the cell is A)  B, which is prometaphase. B)  C, which is metaphase. C)  D, which is anaphase. D)  E, which is telophase. E)  A, which is prophase. -The phase of mitosis in which the chromosomes condense and centrosomes move to opposite poles of the cell is


A) B, which is prometaphase.
B) C, which is metaphase.
C) D, which is anaphase.
D) E, which is telophase.
E) A, which is prophase.

F) All of the above
G) B) and C)

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Before any cell divides into two daughter cells,it must first duplicate its


A) entire genome.
B) cell membrane structure.
C) All of the answer choices are correct.
D) cytoplasmic contents.
E) array of enzymes.

F) D) and E)
G) A) and B)

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After replication,in eukaryotes,both the original and its replicated copy chromosome are each called a


A) chromosome.
B) centromere.
C) chromatin.
D) sister chromatid.
E) nucleosome.

F) A) and D)
G) C) and D)

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What hypothesis did Boehm,et al.develop after testing mice (initially) and eventually humans?


A) Because endostatin works on endothelial cells, natural selection for resistance may arise in tumor cells not initially killed.
B) Because endostatin works on tumor cells, natural selection for resistance will not occur in endothelial cells.
C) Because cyclophosphamide works on endothelial cells, natural selection for resistance will not occur in tumor cells.
D) Because cyclophosphamide works on tumor cells, natural selection for resistance will not occur in endothelial cells.

E) A) and C)
F) None of the above

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A seedling plant has a section of the stem tip that contains large numbers of cells undergoing mitosis for the purpose of


A) sexual reproduction of gametes, to produce new offspring.
B) growth in height of the plant.
C) replication of the DNA in the stem, where new flowers will go through meiosis.
D) asexual reproduction of gametes, to produce new offspring.
E) fertilization of the gametes in order to produce new offspring.

F) A) and D)
G) C) and D)

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Figuer: Figuer:   -What is the dependent variable in this figure? A)  treatment with cyclophosphamide B)  treatment days C)  treatment with endostatin D)  the volume of the tumor -What is the dependent variable in this figure?


A) treatment with cyclophosphamide
B) treatment days
C) treatment with endostatin
D) the volume of the tumor

E) A) and B)
F) A) and C)

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In the biology lab,you are shown petri dishes of cheek cell cultures.One set of cells is thin,with individual cells arranged in a single,orderly layer.The other culture shows irregular crowding of cells.The crowding cells are likely cancer cells,showing an absence of


A) oncogenes.
B) contact inhibition.
C) All of these answers are visually characteristic of cancer cells.
D) angiogenesis.
E) telomerases.

F) B) and C)
G) A) and E)

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Why would a cancer cell need to induce angiogenesis?


A) It would activate oncogenes.
B) Cells in the center of a tumor would benefit from a larger blood supply.
C) Cells could then produce proteins that avoid checkpoints in the cell cycle.
D) It is another name for stage I in metastasis.
E) It would inactivate tumor suppressors.

F) D) and E)
G) B) and E)

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The two main stages of the eukaryote cell cycle,in which the cell spends most of its time and metabolic energy,are


A) interphase and cytokinesis.
B) interphase and binary fission.
C) mitosis and meiosis.
D) interphase and mitosis.
E) mitosis and cytokinesis.

F) A) and D)
G) B) and E)

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Figuer: Figuer:   -What did the researchers conclude based on the data in figure (a) ? A)  Cyclophosphamide delayed the growth of tumors but resistance developed. B)  Endostatin shrunk tumors without development of resistance. C)  Endostatin shrunk tumors but resistance developed. D)  Tumors in untreated cells shrank in size. E)  Cyclophosphamide delayed the growth of tumors without development of resistance. -What did the researchers conclude based on the data in figure (a) ?


A) Cyclophosphamide delayed the growth of tumors but resistance developed.
B) Endostatin shrunk tumors without development of resistance.
C) Endostatin shrunk tumors but resistance developed.
D) Tumors in untreated cells shrank in size.
E) Cyclophosphamide delayed the growth of tumors without development of resistance.

F) A) and C)
G) A) and D)

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The molecule that contains the information for making a cell's proteins and copies itself for the next generation of cells is


A) DNA.
B) ATP synthase.
C) RNA.
D) NAD.
E) FAD.

F) A) and B)
G) All of the above

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The process by which a sperm cell combines with an egg cell is


A) replication.
B) germination.
C) mitosis.
D) fertilization.
E) recombination.

F) A) and D)
G) A) and C)

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Prokaryotic cells reproduce by forming gametes that will unite in fertilization.

A) True
B) False

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If a cancer metastasizes,its cells travel through the bloodstream or the lymphatic system and colonize other areas of the body.

A) True
B) False

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Figuer: This diagram shows the steps in mitosis, with labels to reference in the questions below. Figuer: This diagram shows the steps in mitosis, with labels to reference in the questions below.   -In which of these mitosis phases is the replication of DNA accomplished? A)  None of these answer options are correct, because replication does not happen during mitosis. B)  A, which is mitosis. C)  C, which is telophase. D)  A, which is prophase. E)  E, which is cytokinesis. -In which of these mitosis phases is the replication of DNA accomplished?


A) None of these answer options are correct, because replication does not happen during mitosis.
B) A, which is mitosis.
C) C, which is telophase.
D) A, which is prophase.
E) E, which is cytokinesis.

F) None of the above
G) A) and E)

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Figuer: This diagram shows how DNA is packaged and folded with its associated protective and regulatory proteins. Figuer: This diagram shows how DNA is packaged and folded with its associated protective and regulatory proteins.   -A nucleosome consists of A)  two or more closely related genes. B)  a ribosome and RNA. C)  a stretch of DNA. D)  a stretch of DNA and histones. E)  an RNA molecule. -A nucleosome consists of


A) two or more closely related genes.
B) a ribosome and RNA.
C) a stretch of DNA.
D) a stretch of DNA and histones.
E) an RNA molecule.

F) B) and C)
G) C) and D)

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Apoptosis is a name for the process of


A) mitosis.
B) programmed cellular reproduction.
C) replication.
D) programmed cell death.
E) the cell cycle.

F) All of the above
G) B) and D)

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The process that replicates the DNA,and then divides a prokaryotic cell into two daughter cells is


A) synthesis.
B) replication.
C) metastasis.
D) binary fission.
E) mitosis.

F) C) and D)
G) A) and B)

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Figuer: This diagram shows the steps in mitosis, with labels to reference in the questions below. Figuer: This diagram shows the steps in mitosis, with labels to reference in the questions below.   -The structure that organizes the protein subunits of the mitotic spindle is the A)  centrosome. B)  centromere. C)  microfilaments. D)  kinetochore. E)  cytoskeleton. -The structure that organizes the protein subunits of the mitotic spindle is the


A) centrosome.
B) centromere.
C) microfilaments.
D) kinetochore.
E) cytoskeleton.

F) A) and B)
G) None of the above

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When studying endostatin,why did Boehm et al.induce cancer in mice by injecting cancer cells,instead of just doing the experiment on isolated cancer cells in culture?


A) Oncogenes are only active in whole tumors.
B) Tumor suppressors are only active in whole tumors.
C) Cancer cells can go through angiogenesis in culture.
D) Cancer cells cannot be grown outside of the body in culture.
E) Angiogenesis involves multiple tissues in a whole organism.

F) D) and E)
G) None of the above

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