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If E. coli bacteria are grown in the absence of lactose, then the repressor will


A) not bind the operator allowing transcription of the lac operon genes.
B) bind the operator allowing transcription of the lac operon genes.
C) not bind the operator preventing transcription of the lac operon genes.
D) bind the operator preventing transcription of the lac operon genes.
E) coli bacteria are grown in the absence of lactose, then the repressor will

F) B) and C)
G) B) and D)

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In humans,typically only infants produce the enzyme lactase to break down lactose.Some adults have changes in _____ that allow transcription factors to bind and turn on expression of the lactase gene into adulthood.


A) enhancers
B) mRNA
C) codons
D) exons
E) RNA polymerase

F) B) and E)
G) C) and E)

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If bacteria are infected with bacteriophage containing radioactive ____ the bacteria will now be radioactive.


A) phosphate
B) iron
C) phosphate or sulfur
D) sulfur
E) iron or sulfur

F) B) and C)
G) A) and D)

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DNA genetic coding and cell regulation is now understood to be incredibly important to every cell among organisms, and is also associated with viruses. Through the early and mid 1900s, scientists developed new molecular analysis methods that changed the foundations of how we understand "life" to function. Normal health and homeostasis, as well as disease, and natural variations in form and function among organisms are now better understood. Medical and biological applications have increased dramatically with the understanding of DNA molecule structure, and it is helpful to have recognition of the scientists and sequence of events contributing to our understanding. -The scientist (scientists) who used enzyme-digesting proteins to show that protein was not the genetic information transferred by bacteria is (are)


A) Hershey and Chase.
B) Griffith.
C) Watson and Crick.
D) Avery and Macleod.
E) Wilkins and Franklin.

F) A) and E)
G) A) and D)

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The step of translation in which release factors bind to a stop codon is


A) transcription.
B) mitosis.
C) elongation.
D) termination.
E) initiation.

F) D) and E)
G) A) and D)

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What would be the first codon translated in the mRNA sequence 5'-GGAAUGAAACAGGAACCC-3'?


A) AAU
B) GAA
C) AUG
D) GGA
E) CCC

F) All of the above
G) A) and E)

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C

TheFOXP2 sequences of mice were most different from those of


A) humans.
B) All had the same number of changes from the mouse sequence.
C) chimpanzees.
D) gorillas.
E) rhesus monkeys.

F) All of the above
G) C) and D)

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A DNA sequence that signals a gene's start is a(n)


A) promoter.
B) amino acid attachment site.
C) anticodon.
D) terminator.
E) codon.

F) A) and E)
G) D) and E)

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A diploid cell only has two copies of most genes,but can make hundreds of copies of a protein from those genes per second because


A) the DNA can replicate during transcription, producing double-sided mRNA to accelerate the translation process.
B) multiple ribosomes can actively attach to the template DNA and conduct translation immediately after transcription.
C) multiple codons can encode for the same amino acid, allowing different versions of the protein to be made.
D) while transcription can repeat and make multiple mRNA copies of genes, and multiple ribosomes can translate the same mRNA.
E) multiple copies of the same mRNA can be produced with multiple promoter sequences to simultaneously initiate multiple ribosomes.

F) All of the above
G) B) and E)

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In eukaryotes an mRNA molecule can only be translated by one ribosome at a time.

A) True
B) False

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False

A poly A tail helps attach the ribosome to the mRNA molecule and may also determine how long the mRNA is retained within the cell.

A) True
B) False

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The Human Genome Project is a multinational project that reported complete identification of more than 20,000 genes in human DNA. Growing understanding has associated "normal" and naturally variable versions of the genes, producing specific proteins for human health and cell functions. Numerous mutated versions of the genes have been associated with particular human health problems and disease, due to the types of cells where mutations occur, the specific genes affected, and the type and extent of mutation. In these cases, the structure and function of proteins is ultimately impacted. Examine these examples to apply your knowledge of mutations to the descriptions provided. -Keratins are structural proteins in skin,hair,and fingernails.One gene,called KRT10,is located on the 17th paired chromosome in humans.It produces a keratin that strengthens skin cells.Researchers have identified several mutations that can lead to rough,damaged,blistering skin because the keratins are not as strong as normal.Each mutation changes a specific amino acid at a particular location in the protein,and so is an example of a(n) ______ mutation.


A) duplication
B) nonsense
C) missense
D) insertion
E) frameshift

F) D) and E)
G) All of the above

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Based on this study,FOXP2 must be expressed in which tissues?


A) muscle
B) muscle and nerves in the ear
C) brain
D) muscle and brain
E) nerves in the ear

F) None of the above
G) A) and D)

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The 5' and 3' designations used in reference to DNA and RNA sequences are assigned to the


A) hydrogen atoms that form hydrogen bonds between the nucleotides.
B) nitrogen atoms in the nitrogen bases.
C) carbon atoms in the nitrogen base purines and pyrimidines.
D) oxygen atoms contained in the deoxyribose and ribose.
E) carbon atoms of deoxyribose and ribose.

F) A) and D)
G) C) and E)

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A visiting scientist is introduced to you,and has a current project studying initiation,elongation,and termination.As a result,you know she is studying


A) either transcription or translation.
B) replication and translation.
C) transcription.
D) translation.
E) replication.

F) C) and D)
G) B) and D)

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If you compared the DNA sequence of a gene with the sequence of the mature mRNA that was transcribed from the gene you would find


A) the mRNA is shorter because each codon of three bases encodes only one amino acid.
B) the mRNA is shorter because it does not contain introns.
C) the mRNA is longer because each codon of one amino acid encodes three bases.
D) both are the same length.
E) the mRNA is shorter because it does not contain exons.

F) A) and B)
G) C) and D)

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The statement that does not correctly associate an RNA type,and its function,is


A) complementary RNA reorders the amino acids to insure their correct sequence.
B) messenger RNA is the gene, carrying coding to control the building of proteins.
C) transfer RNA functions to carry amino acids to the ribosome.
D) ribosomal RNA functions as a catalyst to bind amino acids into proteins.

E) C) and D)
F) None of the above

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A

DNA genetic coding and cell regulation is now understood to be incredibly important to every cell among organisms, and is also associated with viruses. Through the early and mid 1900s, scientists developed new molecular analysis methods that changed the foundations of how we understand "life" to function. Normal health and homeostasis, as well as disease, and natural variations in form and function among organisms are now better understood. Medical and biological applications have increased dramatically with the understanding of DNA molecule structure, and it is helpful to have recognition of the scientists and sequence of events contributing to our understanding. -Most bacteriophages consist of only a _______________ coat and a ____________________ core.


A) protein; nucleic acid
B) polysaccharide; protein
C) protein; lipid
D) polysaccharide; nucleic acid
E) lipid; protein

F) All of the above
G) A) and E)

Correct Answer

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There are only two main types of RNA needed to make proteins.They are tRNA and rRNA.

A) True
B) False

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Amanatin,a toxin from the death cap poisonous mushroom,inhibits RNA polymerase,so it


A) prevents the initiator tRNA from beginning translation.
B) incorrectly places the release factor protein on mRNA and terminates translation.
C) stops initiation, elongation, and termination stages of transcription.
D) reverses the direction of RNA polymerase action, tearing apart partially formed proteins.
E) disables any introns from being produced, to complete the protein structures.

F) A) and B)
G) C) and E)

Correct Answer

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