Question 1

An extra three nucleotides inserted into a gene will cause a frameshift mutation.

Accepted Answer

A) True 
 B)False

Question 2

Testing for a protein may help reveal whether or not an individual has a genetic disorder.

Accepted Answer

A) True 
 B)False

Question 3

When a chromosome carrying an inversion undergoes crossing-over

Accepted Answer

A)   all four chromatids of the tetrad will contain a duplication or deletion.
B)   two chromatids will carry both a duplication and a deletion, one will contain the inversion, and one will be normal.
C)   two chromatids will carry both a duplication and a deletion, and the other two will contain the inversion.
D)   all four chromatids will be normal.
E)   two chromatids will carry the inversion, and the other two will be normal.F) None of the above
G) A) and B)

Question 4

Which one of the following diseases or disorders has not been treated using gene therapy methods?

Accepted Answer

A)   rheumatoid arthritis
B)   familial hypercholesterolemia
C)   cri du chat syndrome
D)   sickle cell disease
E)   Duchenne muscular dystrophyF) B) and E)
G) C) and D)

Question 5

Which genetic disorder is due to a deletion on chromosome 7?

Accepted Answer

A)   Williams syndrome
B)   Cri du chat
C)   Alagille syndrome
D)   Down syndrome
E)   cancerF) A) and D)
G) B) and D)

Question 6

Mutant gene alleles associated with known genetic disorders can be detected using DNA microarray analysis.

Accepted Answer

A) True 
 B)False

Question 7

A karyotype shows chromosomes arranged by

Accepted Answer

A)   banding patterns, size, and shape.
B)   shape, size, and complexity.
C)   complexity, radius, and length.
D)   length, structure, and color.
E)   color, width, and length.F) A) and B)
G) D) and E)

Question 8

A translocation chromosomal mutation is the exchange of segments between two homologous chromosomes.

Accepted Answer

A) True 
 B)False

Question 9

Which of the following syndromes is caused by a translocation?

Accepted Answer

A)   Alagille syndrome
B)   invdup 15 syndrome
C)   Williams syndrome
D)   Cri-du-chat syndrome
E)   Turner syndromeF) A) and C)
G) C) and E)

Question 10

Figure: 
-You are a genetic counselor,and a man with the translocation shown in the figure is your client.He and his partner (who has a normal karyotype) wish to have children.You explain to him that the probability of having a child with an unbalanced translocation is

Accepted Answer

A)   0%.
B)   25%.
C)   50%.
D)   75%.
E)   100%.F) B) and C)
G) None of the above

Question 11

Figure: 
-You are a genetic counselor,and a man with the translocation shown in the figure is your client.He and his partner (who has a normal karyotype) wish to have children.You explain to him that the probability of having a child with a normal karyotype is

Accepted Answer

A)   0%.
B)   25%.
C)   50%.
D)   75%.
E)   100%.F) C) and D)
G) A) and E)

Question 12

Chromosome 7 may lose an end piece resulting in Williams syndrome.This is an example of a(n)

Accepted Answer

A)   inversion.
B)   duplication.
C)   deletion.
D)   translocation.
E)   epigenetic inheritance.F) B) and E)
G) All of the above C

Question 13

Which structure is used in the new treatment of rheumatoid arthritis?

Accepted Answer

A)   adenovirus
B)   SCID
C)   bacteriophage
D)   hypodermic needles
E)   None of these structures are used in the treatment of rheumatoid arthritis.F) B) and C)
G) A) and C)

Question 14

A missing piece of chromosome 5 may result in a child whose glottis and larynx do not develop properly resulting in an abnormal cry.This is called

Accepted Answer

A)   Cri du chat syndrome.
B)   Huntington syndrome.
C)   Klinefelter syndrome.
D)   inv dup 15 syndrome.
E)   Down syndrome.F) D) and E)
G) None of the above A

Question 15

Inversions are chromosomal mutations that

Accepted Answer

A)   always result in a syndrome.
B)   neither increase nor decrease the amount of genetic material in the cell.
C)   rarely cause deletions or duplications during gamete formation when crossing-over occurs.
D)   result from duplication of a portion of a chromosome.
E)   never disrupt gene regulation or cause physical abnormalities.F) A) and B)
G) B) and D)

Question 16

Which human disorder is not being treated with gene therapy?

Accepted Answer

A)   severe combined immunodeficiency (SCI
D)  
B)   familial hypercholesterolemia
C)   cancer
D)   cystic fibrosis
E)   All of these are being treated with gene therapy.F) A) and B)
G) None of the above A

Question 17

Transposons have not been discovered in which of the following species?

Accepted Answer

A)   bacteria
B)   plants
C)   humans
D)   fruit flies
E)   fungiF) B) and C)
G) B) and D)

Question 18

Which type of chromosomal mutation will lead to Alagille syndrome?

Accepted Answer

A)   translocation
B)   duplication
C)   inversion
D)   frameshift
E)   point mutationF) C) and D)
G) A) and B)

Question 19

A transposon may cause a mutation if it

Accepted Answer

A)   jumps into an exon of another gene.
B)   jumps into an intron of another gene.
C)   jumps into an intergenic DNA sequence.
D)   remains trapped within an intergenic DNA sequence.
E)   interacts with a physical mutagen.F) A) and B)
G) B) and C)

Question 20

A silent mutation is more likely to occur as a result of

Accepted Answer

A)   a frameshift mutation.
B)   a point mutation that does not change the amino acid encoded within the gene.
C)   the movement of a transposon into an exon.
D)   a point mutation that alters the amino acid encoded within the gene.
E)   a large dose of radiation.F) All of the above
G) A) and E)

Exam 13: Genetic Counseling

An extra three nucleotides inserted into a gene will cause a frameshift mutation.

Correct AnswerverifiedShow Answer

Testing for a protein may help reveal whether or not an individual has a genetic disorder.

Correct AnswerverifiedShow Answer

When a chromosome carrying an inversion undergoes crossing-over

Correct AnswerverifiedShow Answer

Which one of the following diseases or disorders has not been treated using gene therapy methods?

Correct AnswerverifiedShow Answer

Which genetic disorder is due to a deletion on chromosome 7?

Correct AnswerverifiedShow Answer

Mutant gene alleles associated with known genetic disorders can be detected using DNA microarray analysis.

Correct AnswerverifiedShow Answer

A karyotype shows chromosomes arranged by

Correct AnswerverifiedShow Answer

A translocation chromosomal mutation is the exchange of segments between two homologous chromosomes.

Correct AnswerverifiedShow Answer

Which of the following syndromes is caused by a translocation?

Correct AnswerverifiedShow Answer

Figure: -You are a genetic counselor,and a man with the translocation shown in the figure is your client.He and his partner (who has a normal karyotype) wish to have children.You explain to him that the probability of having a child with an unbalanced translocation is

Correct AnswerverifiedShow Answer

Figure: -You are a genetic counselor,and a man with the translocation shown in the figure is your client.He and his partner (who has a normal karyotype) wish to have children.You explain to him that the probability of having a child with a normal karyotype is

Correct AnswerverifiedShow Answer

Chromosome 7 may lose an end piece resulting in Williams syndrome.This is an example of a(n)

Correct AnswerverifiedC

Which structure is used in the new treatment of rheumatoid arthritis?

Correct AnswerverifiedShow Answer

A missing piece of chromosome 5 may result in a child whose glottis and larynx do not develop properly resulting in an abnormal cry.This is called

Correct AnswerverifiedA

Inversions are chromosomal mutations that

Correct AnswerverifiedShow Answer

Which human disorder is not being treated with gene therapy?

Correct AnswerverifiedA

Transposons have not been discovered in which of the following species?

Correct AnswerverifiedShow Answer

Which type of chromosomal mutation will lead to Alagille syndrome?

Correct AnswerverifiedShow Answer

A transposon may cause a mutation if it

Correct AnswerverifiedShow Answer

A silent mutation is more likely to occur as a result of

Correct AnswerverifiedShow Answer

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified
C

Correct Answer
verified

Correct Answer
verified
A

Correct Answer
verified

Correct Answer
verified
A

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified