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DNA can best be described as


A) two backbones of alternating deoxyribose and nitrogenous base on the exterior,with phosphates on the interior
B) two backbones of alternating deoxyribose and nitrogenous base on the interior,with phosphates on the exterior
C) two backbones of alternating deoxyribose and phosphate on the exterior,with nitrogenous bases on the interior
D) two backbones of alternating deoxyribose and phosphate on the interior,with nitrogenous bases on the exterior
E) two backbones of alternating nitrogenous base and phosphate on the exterior,with deoxyriboses on the interior

F) B) and D)
G) A) and E)

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Answer the following questions. a) If the following segment of mRNA (5') CUU-AGC-UGG-CCC (3') was changed to (5') CUU-AGC-UGG-CCU (3') how would the synthesized protein change? b) If the following segment of mRNA (5') CUU-AGC-UGG-CCC (3') was changed to (5') CUU-AGC-UGA-CCU (3') how would the synthesized protein change?

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a) No change, both CCC and CC...

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Base pairs in DNA are


A) parallel to each other and parallel to the long axis of the DNA molecule
B) parallel to each other and perpendicular to the long axis of the DNA molecule
C) parallel to each other,with random orientations to the long axis of the DNA molecule
D) perpendicular to each other,with every other base pair parallel to the long axis of the DNA molecule
E) perpendicular to each other,with random orientations to the long axis of the DNA molecule

F) C) and D)
G) None of the above

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What sequence is fully complementary to the following sequence? (5') ATCTAGTCA (3')


A) (5') TAGATCAGT (3')
B) (5') TGACTAGAT (3')
C) (5') ATCTAGTCA (3')
D) (5') ACTGATCTA (3')

E) B) and C)
F) B) and D)

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Which reagent is used to accelerate coupling reactions in both laboratory peptide synthesis and laboratory DNA synthesis?


A) catalytic H+
B) dicyclohexylcarbodiimide (DCC)
C) ethyl chloroformate
D) NaOH
E) PhS- NH4+

F) B) and D)
G) A) and B)

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B

What is the anticodon sequence in tRNA that corresponds the following segment of mRNA? (5')CUU-AGC-UGG-CCC(3')

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(3')GAA-UC...

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What mRNA sequence is complementary to the following DNA base sequence? (5')TAAGGCGATA (3')

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(3')AUUCCG...

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Which of the following represents the general sequence of events in the catabolism of nucleic acids?


A) hydrolysis,dephosphorylation,cleavage of the sugar
B) cleavage of the sugar,dephosphorylation,hydrolysis
C) dephosphorylation,hydrolysis,cleavage of the sugar
D) hydrolysis,cleavage of the sugar,dephosphorylation
E) dephosphorylation,cleavage of the sugar,hydrolysis

F) A) and D)
G) A) and B)

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Which of the following is a definition of messenger RNA (mRNA) ?


A) RNA found in the ribosome,the site in cells where synthesis of proteins takes place
B) RNA which carries a specific amino acid to the site of protein synthesis
C) RNA which has coded genetic information
D) RNA which signals cell death

E) None of the above
F) B) and D)

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How many hydrogen bonds are present in a G-C base pair and an A-T base pair,respectively?


A) 1,2
B) 2,2
C) 2,3
D) 3,2
E) 3,3

F) A) and B)
G) A) and C)

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D

Which is true?


A) Both DNA and RNA are completely double-stranded.
B) Both DNA and RNA are completely single-stranded.
C) Both DNA and RNA contain ribose.
D) Both DNA and RNA contain uracil.
E) Both DNA and RNA contain phosphate.

F) C) and D)
G) All of the above

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Which of the following characterizes the polymerase chain reaction (PCR) ?


A) produces multiple copies of DNA segments
B) requires small amount of the source DNA
C) the key to the process is a thermally stable enzyme
D) involves temperature cycling
E) all of these

F) A) and E)
G) A) and D)

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Which of the following is uridine? Which of the following is uridine?   A) 1 B) 2 C) 3 D) 4


A) 1
B) 2
C) 3
D) 4

E) A) and C)
F) All of the above

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Rank DNA,mRNA,and tRNA from largest to smallest.


A) DNA > mRNA > tRNA
B) DNA > tRNA > mRNA
C) mRNA > tRNA > DNA
D) mRNA > DNA > tRNA
E) tRNA > mRNA > DNA

F) A) and E)
G) B) and E)

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In some instances,base pairs other than the familiar G-C and A-T matches can form.For these alternate pairs to form,one of the two bases must tautomerize.Based on this information,draw a C-A pair and determine the number of hydrogen bonds that would stabilize the pair.

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Two hydrog...

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Describe,in general terms,the steps involved in the automated synthesis of the DNA sequence GCT.

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A double-stranded DNA molecule that contains 22%,on a mole basis,T must also contain


A) 11% G
B) 22% G
C) 28% G
D) 56% G
E) 78% G

F) A) and B)
G) D) and E)

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What sequence of bases on the second strand of DNA is complementary to the following? (5')GCATTA (3')

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(3')CGTAAT (5')or (5')TAATGC (3')

What amino acid sequence is coded by the following segment of DNA? (5')TTA-GCC-GTA-CTA-AAA (3')

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Asn-Arg-Hi...

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The bond between the nitrogenous base and the sugar in a nucleoside is a glycosidic bond.Which type of reagent should cleave this bond?


A) acid
B) base
C) acid or base
D) neither acid nor base
E) It depends on which nitrogenous base and which sugar are present.

F) None of the above
G) A) and E)

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