Question 1

Classify each of the following species ,Place the letter of the choice in the blank to the left of the formula.
-________

Accepted Answer

A)  an electrophile.
B)  a nucleophile.
C)  either an electrophile or a nucleophile.D) A) and B)
E) A) and C)

Question 2

The reaction of methyl iodide with sodium azide, NaN3, proceeds by an SN2 mechanism. What is the effect of doubling the concentration of NaN3 on the rate of the reaction?

Accepted Answer

A)  the rate remains the same
B)  the rate decreases by a factor of 2
C)  the rate increases by a factor of 2
D)  the rate increases by a factor of 4E) B) and C)
F) B) and D)

Question 3

In the following reaction the cyanide ion is both a nucleophile and a Lewis acid.

Accepted Answer

A) True 
 B)False

Question 4

Which of the following represents the transition state of the rate-determining step in the reaction between 2-bromopropane and sodium methoxide leading to elimination?

Accepted Answer

A)  1
B)  2
C)  3
D)  4E) C) and D)
F) B) and D)

Question 5

Which of the following alkyl bromides reacts the slowest with NaSCH3 in DMF? 3 in DMF?   A) 1 B) 2 C) 3 D) 4" class="answers-bank-image d-inline" rel="preload" >

Accepted Answer

A)  1
B)  2
C)  3
D)  4E) None of the above
F) All of the above

Question 6

The reaction of 1-bromopropane with sodium iodide gives 1-iodopropane. What is the effect of doubling the concentration of NaI on the rate of the reaction?

Accepted Answer

A)  the rate remains the same
B)  the rate decreases by a factor of 2
C)  the rate increases by a factor of 2
D)  the rate increases by a factor of 4E) All of the above
F) B) and D)

Question 7

What is the best choice of reagent to perform the following transformation? 2SO4 B) H2O C) NaOCH3 D) KOtBu" class="answers-bank-image d-inline" rel="preload" >

Accepted Answer

A)  H2SO4
B)  H2O
C)  NaOCH3
D)  KOtBuE) A) and B)
F) A) and C)

Question 8

The rate law for the following reaction would be of the form Rate = k[A][B].

Accepted Answer

A) True 
 B)False

Question 9

For each substrate below, choose which reaction type is favored. Place the letter of the reaction type in the blank to the left of the substrate.
-______ N1 B) SN2 C) E1 D) E2" class="answers-bank-image d-inline" rel="preload" >

Accepted Answer

A)  SN1
B)  SN2
C)  E1
D)  E2E) B) and D)
F) None of the above

Question 10

What is the major elimination product obtained from the following reaction?

Accepted Answer

A)  1
B)  2
C)  3
D)  4E) A) and D)
F) B) and C)

Question 11

What is the major organic product obtained from the following reaction?

Accepted Answer

The answer of What is the major organic product obtained...

Question 12

Which of the following energy diagrams represents the course of an exothermic SN1 reaction? N1 reaction?   A) 1 B) 2 C) 3 D) 4" class="answers-bank-image d-inline" rel="preload" >

Accepted Answer

A)  1
B)  2
C)  3
D)  4E) B) and D)
F) A) and B)

Question 13

What is the major organic product obtained from the following reaction?

Accepted Answer

The answer of What is the major organic product obtained...

Question 14

Which of the following reactions corresponds to a substitution?

Accepted Answer

A)  propene  →\rarr→  1,2-dibromopropane
B)  1-iodopropane  →\rarr→  propene
C)  propene  →\rarr→  propane
D)  1-iodopropane  →\rarr→  1-bromopropane E) A) and B)
F) B) and C)

Question 15

Which of the following represents the transition state of the reaction between methyl bromide and sodium methylthiolate, NaSCH3? 3?   A) 1 B) 2 C) 3 D) 4" class="answers-bank-image d-inline" rel="preload" >

Accepted Answer

A)  1
B)  2
C)  3
D)  4E) A) and B)
F) A) and C)

Question 16

Which of the following energy diagrams represents the course of an exothermic E1 reaction?

Accepted Answer

A)  1
B)  2
C)  3
D)  4E) C) and D)
F) B) and D)

Question 17

Provide a neatly drawn mechanism for the following reaction, including curved arrows to show the movement of pairs of electrons and the structure of reactive intermediates.

Accepted Answer

The reaction proceeds in a sin...

Question 18

The first step in the mechanism for the following reaction would be the formation of a secondary carbocation.

Accepted Answer

A) True 
 B)False

Question 19

Which of the following represents the transition state of the rate-determining step in the reaction between tert-butyl bromide and methanol leading to elimination?

Accepted Answer

A)  1
B)  2
C)  3
D)  4E) C) and D)
F) All of the above

Question 20

What is the major organic product obtained from the following reaction?

Accepted Answer

The answer of What is the major organic product obtained...

Exam 9: Nucleophilic Substitution and Beta-Elimination

The reaction of methyl iodide with sodium azide, NaN3, proceeds by an SN2 mechanism. What is the effect of doubling the concentration of NaN3 on the rate of the reaction?

Correct AnswerverifiedShow Answer

What is the major organic product obtained from the following reaction?

Correct AnswerverifiedShow Answer

What is the major organic product obtained from the following reaction?

Correct AnswerverifiedShow Answer

For each substrate below, choose which reaction type is favored. Place the letter of the reaction type in the blank to the left of the substrate. -______

Correct AnswerverifiedShow Answer

Which of the following represents the transition state of the rate-determining step in the reaction between tert-butyl bromide and methanol leading to elimination?

Correct AnswerverifiedShow Answer

The first step in the mechanism for the following reaction would be the formation of a secondary carbocation.

Correct AnswerverifiedShow Answer

What is the major elimination product obtained from the following reaction?

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The reaction of 1-bromopropane with sodium iodide gives 1-iodopropane. What is the effect of doubling the concentration of NaI on the rate of the reaction?

Correct AnswerverifiedShow Answer

What is the major organic product obtained from the following reaction?

Correct AnswerverifiedShow Answer

Provide a neatly drawn mechanism for the following reaction, including curved arrows to show the movement of pairs of electrons and the structure of reactive intermediates.

Correct AnswerverifiedThe reaction proceeds in a sin...View AnswerShow Answer

Which of the following alkyl bromides reacts the slowest with NaSCH3 in DMF?

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Classify each of the following species ,Place the letter of the choice in the blank to the left of the formula. -________

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Which of the following energy diagrams represents the course of an exothermic E1 reaction?

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Which of the following represents the transition state of the rate-determining step in the reaction between 2-bromopropane and sodium methoxide leading to elimination?

Correct AnswerverifiedShow Answer

Which of the following represents the transition state of the reaction between methyl bromide and sodium methylthiolate, NaSCH3?

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In the following reaction the cyanide ion is both a nucleophile and a Lewis acid.

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Which of the following reactions corresponds to a substitution?

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The rate law for the following reaction would be of the form Rate = k[A][B].

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What is the best choice of reagent to perform the following transformation?

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Which of the following energy diagrams represents the course of an exothermic SN1 reaction?

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The reaction of methyl iodide with sodium azide, NaN₃, proceeds by an S_N2 mechanism. What is the effect of doubling the concentration of NaN₃ on the rate of the reaction?

Correct Answer
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The reaction proceeds in a sin...
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Which of the following alkyl bromides reacts the slowest with NaSCH₃ in DMF?

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Which of the following represents the transition state of the reaction between methyl bromide and sodium methylthiolate, NaSCH₃?

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Which of the following energy diagrams represents the course of an exothermic S_N1 reaction?

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