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Consider the following compounds. Consider the following compounds.   Answer the following questions by filling in the blank with the appropriate number from the diagram or an appropriate term. -The ammonia ion of substance ____ will have the largest pK<sub>a</sub>. Answer the following questions by filling in the blank with the appropriate number from the diagram or an appropriate term. -The ammonia ion of substance ____ will have the largest pKa.

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What is the major organic product obtained from the following sequence of reactions? What is the major organic product obtained from the following sequence of reactions?   A) 1 B) 2 C) 3 D) 4


A) 1
B) 2
C) 3
D) 4

E) B) and D)
F) B) and C)

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What is the major organic product obtained from the following sequence of reactions? What is the major organic product obtained from the following sequence of reactions?   A) 1 B) 2 C) 3 D) 4


A) 1
B) 2
C) 3
D) 4

E) A) and D)
F) None of the above

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Provide a brief explanation, based on features of the molecules, for the following difference in pKa values? CH3NH2 > NH3 10.64 9.26

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The methyl group of methanamine is a wea...

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Aliphatic 3o amines with three different groups on nitrogen can be resolved.

A) True
B) False

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What is the intermediate in the Hofmann elimination, in which a 1 \circ or 2 \circ alkyl halide is treated with trimethyl amine, followed by addition of silver(I) oxide and heat?


A) a tetraalkylammonium hydroxide salt
B) a tertiary amine
C) a 3 \circ carbocation
D) an amine oxide

E) A) and B)
F) All of the above

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What is the major organic product obtained from the following reaction? What is the major organic product obtained from the following reaction?   A) 1 B) 2 C) 3 D) 4


A) 1
B) 2
C) 3
D) 4

E) None of the above
F) A) and C)

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What is the correct assignment of the names of the functional groups in the following nitrogen-containing compounds?  What is the correct assignment of the names of the functional groups in the following nitrogen-containing compounds?   A) 1 = 2<sup> \circ </sup> amine; 2 = enamine; 3 = hydrazine B) 1 = 2<sup> \circ </sup> amine; 2 = amide; 3 = nitrile C) 1 =oxime; 2 = hydrazone; 3 = nitrile D) 1 = imine; 2 = hydrazone; 3 = amide


A) 1 = 2 \circ amine; 2 = enamine; 3 = hydrazine
B) 1 = 2 \circ amine; 2 = amide; 3 = nitrile
C) 1 =oxime; 2 = hydrazone; 3 = nitrile
D) 1 = imine; 2 = hydrazone; 3 = amide

E) B) and C)
F) All of the above

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What is the major organic product obtained from the following reaction? What is the major organic product obtained from the following reaction?   A) 1 B) 2 C) 3 D) 4


A) 1
B) 2
C) 3
D) 4

E) C) and D)
F) B) and D)

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Which of the following compounds are primary (1 \circ ) amines?  Which of the following compounds are primary (1<sup> \circ </sup>)  amines?   A) 1 and 2 B) 1 and 3 C) 1, 2 and 3 D) 1, 2, 3 and 4


A) 1 and 2
B) 1 and 3
C) 1, 2 and 3
D) 1, 2, 3 and 4

E) None of the above
F) A) and B)

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What is the major organic product obtained from the following sequence of reactions? What is the major organic product obtained from the following sequence of reactions?

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What is the intermediate in the Cope elimination, in which a 3 \circ amine is treated with hydrogen peroxide followed by heat?


A) a tetraalkylammonium hydroxide salt
B) an amine oxide
C) a 3 \circ carbocation
D) an amide anion

E) B) and D)
F) B) and C)

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Provide a line-bond structure of N-methylaniline.

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The following represents an acid-base reaction between the given amine and HCl. The following represents an acid-base reaction between the given amine and HCl.

A) True
B) False

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What is the major organic product obtained from the following sequence of reactions? What is the major organic product obtained from the following sequence of reactions?   A) 1 B) 2 C) 3 D) 4


A) 1
B) 2
C) 3
D) 4

E) A) and C)
F) B) and C)

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What is the major organic product obtained from the following sequence of reactions (assume that mixtures of ortho and para disubstituted compounds can be separated; continue the synthesis with either one)? What is the major organic product obtained from the following sequence of reactions (assume that mixtures of ortho and para disubstituted compounds can be separated; continue the synthesis with either one)?

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What is the major organic product obtained from the following reaction? What is the major organic product obtained from the following reaction?   A) 1 B) 2 C) 3 D) 4


A) 1
B) 2
C) 3
D) 4

E) A) and D)
F) A) and C)

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What is the major organic product obtained from the following sequence of reactions (assume that mixtures of ortho and para disubstituted compounds can be separated; continue the synthesis with either one)? What is the major organic product obtained from the following sequence of reactions (assume that mixtures of ortho and para disubstituted compounds can be separated; continue the synthesis with either one)?

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What is the major organic product obtained from the following sequence of reactions? What is the major organic product obtained from the following sequence of reactions?   A) 1 B) 2 C) 3 D) 4


A) 1
B) 2
C) 3
D) 4

E) B) and D)
F) A) and B)

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Which of the following amines can be prepared by reduction of an amide?


A) tert-butyl amine
B) 2-hexanamine
C) N-methyl-1-butanamine
D) aniline

E) None of the above
F) A) and B)

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