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T cells undergo positive selection in the thymus,which means they __________.


A) react against self antigens
B) develop surface antigen receptors
C) remain alive but unresponsive
D) die and macrophages phagocytize them
E) multiply and form clones of identical T cells

F) B) and E)
G) C) and D)

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Naive T cells can synthesize antibodies.

A) True
B) False

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Cytotoxic T cells respond only to antigens bound to MHC-I proteins.

A) True
B) False

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Which of the following forces does not help lymph to flow?


A) Rhythmic contractions of lymphatic vessels
B) The thoracic pump
C) The skeletal muscle pump
D) The lymphatic node pump
E) Arterial pulsations squeezing lymphatic vessels

F) A) and E)
G) C) and D)

Correct Answer

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The immune system spans nearly every organ and tissue in the human body.

A) True
B) False

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Some antibodies against foreign antigens can react to similar self-antigens,causing an autoimmune disease.

A) True
B) False

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The only lymphatic organ(s) with afferent lymphatic vessels is(are) the __________.


A) lymph nodes
B) thymus
C) spleen
D) red bone marrow
E) tonsils

F) A) and E)
G) B) and C)

Correct Answer

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Interferons are secreted in response to bacterial infections.

A) True
B) False

Correct Answer

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__________ is not a cardinal sign characteristic of inflammation.


A) Impaired use
B) Redness
C) Pain
D) Heat
E) Swelling

F) A) and B)
G) D) and E)

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The antigenicity of a molecule is due to specific regions of it called haptens.

A) True
B) False

Correct Answer

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Helper T (TH) cells do not __________.


A) secrete cytokines that stimulate clonal selection of B cells
B) secrete cytokines that stimulate clonal selection of cytotoxic T cells
C) secrete cytokines that stimulate macrophage activity
D) secrete inflammatory chemicals
E) secrete fever-producing chemicals

F) B) and E)
G) A) and D)

Correct Answer

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The lymphatic system is involved in circulation,immunity,and nutrient absorption.

A) True
B) False

Correct Answer

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Removal of the __________ would be more harmful to a one-year-old child than an adult.


A) spleen
B) lymph node
C) thymus
D) appendix
E) palatine tonsil

F) D) and E)
G) A) and B)

Correct Answer

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Pus is made of dead neutrophils,macrophages,and other tissue debris from a damaged tissue.

A) True
B) False

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Cellular immunity uses MHC-I and MHC-II,but humoral immunity uses only MHC-II.

A) True
B) False

Correct Answer

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Which is the correct sequence of events in the humoral immune response?


A) Antigen recognition → antigen presentation → differentiation → clonal selection → attack
B) Antigen recognition → antigen presentation → clonal selection → differentiation → attack
C) Antigen presentation → antigen recognition → clonal selection → differentiation → attack
D) Antigen presentation → antigen recognition → clonal selection → attack differentiation
E) Antigen recognition → differentiation → antigen presentation → clonal selection → attack

F) B) and E)
G) A) and B)

Correct Answer

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Red bone marrow is the point of origin of all immune cells of the lymphatic system.

A) True
B) False

Correct Answer

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The __________ show(s) a remarkable degree of degeneration (involution) with age.


A) lymph nodes
B) thymus
C) spleen
D) pharyngeal tonsils
E) appendix

F) D) and E)
G) None of the above

Correct Answer

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Interleukins are chemical signals by which immune cells communicate with each other.

A) True
B) False

Correct Answer

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Immune surveillance is a process in which __________ nonspecifically detect and destroy foreign cells and diseased host cells.


A) T lymphocytes (T cells)
B) reticular cells
C) dendritic cells
D) macrophages
E) natural killer (NK) cells

F) A) and E)
G) B) and E)

Correct Answer

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