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Which of the following is NOT a concern over the use of genetically engineered corn?


A) resistance among populations of certain pests
B) resistance to herbicides and pesticides
C) genetic exchange between engineered plants and related species
D) impact of engineered plants on nontarget plant species
E) presence of allergens

F) D) and E)
G) A) and C)

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Which species has an estimated 6,300 genes in its genome?


A) yeast
B) roundworms
C) human beings
D) fruit flies
E) mice

F) A) and B)
G) B) and D)

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All of the following are benefits of sequencing the human genome except


A) knowing the exact sequence of DNA in an individual could allow pharmaceutical companies to design drugs for their exact genotype.
B) the discovery of the chemical makeup of DNA.
C) determining individuals who have a predisposing factor that could lead to future illness could allow for earlier treatment.
D) the improvement of sequencing technology that will allow the genomes of other species to be more readily sequenced.
E) enabling scientists to sequence the genome of various other organisms.

F) A) and B)
G) A) and E)

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The aim of functional genomics is to understand the function of the various genes discovered within each genomic sequence and how these genes interact.

A) True
B) False

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When creating transgenic animals,as contrasted with the creation of transgenic bacteria,


A) it is necessary to carry out the procedure completely by hand.
B) animals need donor eggs to contain the genetic material,while bacteria can have the new genes inserted into any bacterial cell.
C) transgenic animals can be created in large numbers,while bacteria must be created one at a time to control contamination.
D) the membranes of the bacteria must be disrupted to allow the genes to be taken up into the cell and animals do not require the host cell membrane to be disrupted.
E) the membranes of the animal cell must be disrupted to allow the genes to be taken up into the cell and bacteria do not require the host cell membrane to be disrupted.

F) A) and C)
G) C) and D)

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In STR,short tandem repeat,profiling,both _______________ and _____________________ are used to identify an individual.


A) length or the repeated sequence; number of fragments
B) rDNA; tRNA
C) specific genetic sequences; types of mRNA
D) mitochondrial DNA; number of fragments
E) mitochondrial DNA; specific genetic sequences

F) D) and E)
G) None of the above

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Bacteria,plants,and animals have all been used to create transgenic forms that are useful in


A) producing high-yield tomato plants.
B) creating pest-resistant versions of corn.
C) cleaning up oil spills.
D) generating pharmaceuticals.
E) producing new types of high-yield beef.

F) B) and E)
G) A) and E)

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Which technique is used to create billions of copies of DNA in a short amount of time?


A) polymerase chain reaction
B) recombinant DNA technology
C) short tandem repeat (STR) profiling
D) gene therapy
E) None of the answer choices is correct.

F) B) and E)
G) A) and D)

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Ex vivo gene therapy


A) requires the removal of cells from the individual undergoing the treatment and then the reintroduction of these cells once they have been genetically modified.
B) requires the use of an agent to introduce genetic material directly into the body using a vector such as an adenovirus vector.
C) has few or no side effects on the individual receiving the treatment.
D) allows for a wider range of disorders to be treated than in vivo treatments.
E) is considered to be more dangerous for the patient than in vivo treatment.

F) C) and D)
G) A) and E)

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A piece of DNA that contains sequences from two or more different organisms is called ______ DNA.


A) inverse
B) species-specific
C) recombinant
D) transgenic
E) semiconservative

F) A) and B)
G) D) and E)

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The purpose of PCR is to create


A) fragments of DNA that are different lengths.
B) recombinant DNA.
C) billions of copies of a segment of DNA.
D) plasmids to be used as vectors in cloning.
E) transgenic crop plants.

F) C) and D)
G) A) and B)

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The treatment of a disorder by inserting genetic material into an organism is called


A) karyotyping.
B) amniocentesis.
C) genetic profiling.
D) chorionic villi sampling.
E) gene therapy.

F) A) and B)
G) All of the above

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Which technique is preferred when investigators are trying to DNA fingerprint an individual?


A) short tandem repeat (STR)
B) polymerase chain reaction (PCR)
C) recombinant DNA (rDNA)
D) gene cloning
E) None of the answer choices is correct.

F) D) and E)
G) C) and D)

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How can comparative genomics assist in the treatment of HIV?


A) The genome of HIV can now be compared to the human genome to find similarities between the two.
B) Knowing the genome of HIV allows for the manufacture of designer drugs to treat specific strains.
C) Understanding the genetic code of HIV allows scientists to replicate it in the laboratory.
D) Understanding the evolution of HIV in an individual will help scientists understand how the virus responds to different drug regimes and will lead to better treatments.
E) Knowing the proteins produced by HIV will allow the development of drugs to mimic those proteins.

F) A) and C)
G) None of the above

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When creating transgenic bacteria,plants,and animals


A) any cell may be used as long as is does not have a cell wall.
B) only eggs may be used for animals,while any cell may be used for plants and bacteria.
C) only eggs may be used for plants and animals,while any cell may be used for bacteria.
D) only eggs may be used to create any transgenic organism.
E) transgenic bacteria are created first and then used to create transgenic plants and animals.

F) A) and D)
G) B) and D)

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Which of the following statements was discovered by information gained from the human genome project?


A) Large sections of the human genome do not code for a polypeptide.
B) Nucleotides are composed of a pentose sugar,a phosphate group,and one of four nitrogenous bases.
C) DNA carries the information to make a polypeptide.
D) Regulation of gene expression determines the specialization of cells in humans.
E) DNA carries the information to make mRNA.

F) All of the above
G) A) and B)

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Gene therapy may be used in the future to fight cancer by inserting genes that


A) fight off mutations of the patient's DNA.
B) produce radioactive isotopes.
C) cause cell death.
D) produce anticancer drugs.
E) All of the answer choices are correct.

F) C) and E)
G) All of the above

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List the number of chromosomes and estimated number of genes for each of the following organisms: 1.Homo sapiens 2.Mus musculus 3.Drosophilia melanogaster 4.Caenorhabditis elegans 5.Saccharomyces cerevisiae

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Species # of Chromosomes # of ...

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One of the problems that limits the use of gene therapy is


A) the finding of suitable donors.
B) some patients are allergic to the bacterial DNA used.
C) mutation of the patient's genes caused by the therapy.
D) detrimental side effects from the inserted genes.
E) All of the answer choices are problems with gene therapy.

F) B) and E)
G) A) and E)

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The study of proteomics is more complex than the study of genomics because


A) proteins are more complex than DNA.
B) proteins are harder to sequence than DNA.
C) there are 20 amino acids that comprise proteins and only 4 nucleotides that compose DNA.
D) scientists understand less about amino acids than they do about nucleotides.
E) each cell in an organism has exactly the same DNA but different cell types each produce different types of proteins.

F) None of the above
G) A) and C)

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